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Safe deployment of deep learning systems in critical real world applications requires models to make very few mistakes, and only under predictable circumstances. In this work, we address this problem using an abstaining classifier that is…

Artificial intelligence methods including deep neural networks (DNN) can provide rapid molecular classification of tumors from routine histology with accuracy that matches or exceeds human pathologists. Discerning how neural networks make…

Image-based diagnostic decision support systems (DDSS) utilizing deep learning have the potential to optimize clinical workflows. However, developing DDSS requires extensive datasets with expert annotations and is therefore costly.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Helen Schneider , Sebastian Nowak , Aditya Parikh , Yannik C. Layer , Maike Theis , Wolfgang Block , Alois M. Sprinkart , Ulrike Attenberger , Rafet Sifa

Pancreatic ductal adenocarcinoma (PDAC) is the third most common cause of cancer death in the United States. Predicting tumors like PDACs (including both classification and segmentation) from medical images by deep learning is becoming a…

Computer Vision and Pattern Recognition · Computer Science 2021-06-01 Yan Wang , Peng Tang , Yuyin Zhou , Wei Shen , Elliot K. Fishman , Alan L. Yuille

Calibrating deep learning models to yield uncertainty-aware predictions is crucial as deep neural networks get increasingly deployed in safety-critical applications. While existing post-hoc calibration methods achieve impressive results on…

Machine Learning · Computer Science 2023-07-06 Christian Tomani , Futa Waseda , Yuesong Shen , Daniel Cremers

Breast cancer is one of the main causes of cancer death worldwide. Early diagnostics significantly increases the chances of correct treatment and survival, but this process is tedious and often leads to a disagreement between pathologists.…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Alexander Rakhlin , Alexey Shvets , Vladimir Iglovikov , Alexandr A. Kalinin

Cell detection in histopathology images is of great value in clinical practice. \textit{Convolutional neural networks} (CNNs) have been applied to cell detection to improve the detection accuracy, where cell annotations are required for…

Computer Vision and Pattern Recognition · Computer Science 2021-07-01 Zipei Zhao , Fengqian Pang , Zhiwen Liu , Chuyang Ye

The recent advances in deep learning predominantly construct models in their internal representations, and it is opaque to explain the rationale behind and decisions to human users. Such explainability is especially essential for domain…

Computer Vision and Pattern Recognition · Computer Science 2022-11-16 Yiheng Zhang , Ting Yao , Zhaofan Qiu , Tao Mei

Deep neural network models can learn clinically relevant features from millions of histopathology images. However generating high-quality annotations to train such models for each hospital, each cancer type, and each diagnostic task is…

Histopathological images (HI) encrypt resolution dependent heterogeneous textures & diverse color distribution variability, manifesting in micro-structural surface tissue convolutions. Also, inherently high coherency of cancerous cells…

Computer Vision and Pattern Recognition · Computer Science 2019-03-26 Sawon Pratiher , Subhankar Chattoraj

We introduce a novel method to combat label noise when training deep neural networks for classification. We propose a loss function that permits abstention during training thereby allowing the DNN to abstain on confusing samples while…

Machine Learning · Statistics 2019-08-05 Sunil Thulasidasan , Tanmoy Bhattacharya , Jeff Bilmes , Gopinath Chennupati , Jamal Mohd-Yusof

Task-agnostic prompt compression leverages the redundancy in natural language to reduce computational overhead and enhance information density within prompts, especially in long-context scenarios. Existing methods predominantly rely on…

Computation and Language · Computer Science 2025-07-17 Yi Zhao , Zuchao Li , Hai Zhao , Baoyuan Qi , Guoming Liu

Machine-learning-assisted cancer subtyping is a promising avenue in digital pathology. Cancer subtyping models, however, require careful training using expert annotations so that they can be inferred with a degree of known certainty (or…

Breast cancer remains a leading cause of cancer-related mortality worldwide. Early detection is critical, yet manual histopathology analysis is complex and subject to inter-observer variability. While deep neural network-based diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Gul Sheeraz , Qun Chen , Liu Feiyu , Zhou Fengjin

Breast cancer is one of the leading causes of death across the world in women. Early diagnosis of this type of cancer is critical for treatment and patient care. Computer-aided detection (CAD) systems using convolutional neural networks…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Sara Hosseinzadeh Kassani , Peyman Hosseinzadeh Kassani , Michal J. Wesolowski , Kevin A. Schneider , Ralph Deters

Cell detection in histopathology images is of great interest to clinical practice and research, and convolutional neural networks (CNNs) have achieved remarkable cell detection results. Typically, to train CNN-based cell detection models,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-17 Zipei Zhao , Fengqian Pang , Yaou Liu , Zhiwen Liu , Chuyang Ye

Timely cancer reporting data are required in order to understand the impact of cancer, inform public health resource planning and implement cancer policy especially in Sub Saharan Africa where the reporting lag is behind world averages.…

Machine Learning · Computer Science 2020-09-02 Waheeda Saib , Tapiwa Chiwewe , Elvira Singh

Backdoor attacks pose severe security threats to deep neural networks by embedding malicious triggers that force misclassification. While machine unlearning techniques can remove backdoor behaviors, current methods lack transparency and…

Cryptography and Security · Computer Science 2025-11-27 Tien Dat Hoang

Breast cancer is one of the most common causes of cancer-related death in women worldwide. Early and accurate diagnosis of breast cancer may significantly increase the survival rate of patients. In this study, we aim to develop a fully…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Sara Hosseinzadeh Kassani , Peyman Hosseinzadeh Kassani , Michal J. Wesolowski , Kevin A. Schneider , Ralph Deters
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