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Many biological and medical tasks require the delineation of 3D curvilinear structures such as blood vessels and neurites from image volumes. This is typically done using neural networks trained by minimizing voxel-wise loss functions that…

Computer Vision and Pattern Recognition · Computer Science 2022-12-27 Doruk Oner , Hussein Osman , Mateusz Kozinski , Pascal Fua

Detection of curvilinear structures in images has long been of interest. One of the most challenging aspects of this problem is inferring the graph representation of the curvilinear network. Most existing delineation approaches first…

Computer Vision and Pattern Recognition · Computer Science 2019-05-13 Agata Mosinska , Mateusz Kozinski , Pascal Fua

Understanding how distributed brain regions coordinate to produce behavior requires models that are both predictive and interpretable. We introduce Behavior-Adaptive Connectivity Estimation (BACE), an end-to-end framework that learns…

Neurons and Cognition · Quantitative Biology 2025-10-27 Mehrnaz Asadi , Sina Javadzadeh , Rahil Soroushmojdehi , S. Alireza Seyyed Mousavi , Terence D. Sanger

Accurate segmentation of thin, tubular structures (e.g., blood vessels) is challenging for deep neural networks. These networks classify individual pixels, and even minor misclassifications can break the thin connections within these…

Convolutional neural networks for semantic segmentation suffer from low performance at object boundaries. In medical imaging, accurate representation of tissue surfaces and volumes is important for tracking of disease biomarkers such as…

Image and Video Processing · Electrical Eng. & Systems 2019-08-13 Francesco Caliva , Claudia Iriondo , Alejandro Morales Martinez , Sharmila Majumdar , Valentina Pedoia

Blood vessel segmentation is one of the most studied topics in computer vision, due to its relevance in daily clinical practice. Despite the evolution the field has been facing, especially after the dawn of deep learning, important…

Image and Video Processing · Electrical Eng. & Systems 2021-08-02 R. J. Araújo , J. S. Cardoso , H. P. Oliveira

Learning-based methods have become increasingly popular for solving vehicle routing problems due to their near-optimal performance and fast inference speed. Among them, the combination of deep reinforcement learning and graph representation…

Machine Learning · Computer Science 2024-05-22 Zhenwei Wang , Ruibin Bai , Fazlullah Khan , Ender Ozcan , Tiehua Zhang

The efficacy of segmentation algorithms is frequently compromised by topological errors like overlapping regions, disrupted connections, and voids. To tackle this problem, we introduce a novel loss function, namely Topology-Aware Focal Loss…

Image and Video Processing · Electrical Eng. & Systems 2023-04-28 Andac Demir , Elie Massaad , Bulent Kiziltan

Learning to compute, the ability to model the functional behavior of a circuit graph, is a fundamental challenge for graph representation learning. Yet, the dominant paradigm is architecturally mismatched for this task. This flawed…

Artificial Intelligence · Computer Science 2026-02-10 Ziyang Zheng , Jiaying Zhu , Jingyi Zhou , Qiang Xu

Segmenting curvilinear structures in medical images is essential for analyzing morphological patterns in clinical applications. Integrating topological properties, such as connectivity, improves segmentation accuracy and consistency.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Zhuangzhi Gao , Feixiang Zhou , He Zhao , Xiuju Chen , Xiaoxin Li , Qinkai Yu , Yitian Zhao , Alena Shantsila , Gregory Y. H. Lip , Eduard Shantsila , Yalin Zheng

Semantic segmentation is a core task in computer vision with applications in biomedical imaging, remote sensing, and autonomous driving. While standard loss functions such as cross-entropy and Dice loss perform well in general cases, they…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Renhao Lu

Segmentation algorithms are prone to make topological errors on fine-scale structures, e.g., broken connections. We propose a novel method that learns to segment with correct topology. In particular, we design a continuous-valued loss…

Computer Vision and Pattern Recognition · Computer Science 2019-06-18 Xiaoling Hu , Li Fuxin , Dimitris Samaras , Chao Chen

Nowadays U-net-like FCNs predominate various biomedical image segmentation applications and attain promising performance, largely due to their elegant architectures, e.g., symmetric contracting and expansive paths as well as lateral…

Computer Vision and Pattern Recognition · Computer Science 2019-09-11 Yanhao Zhu , Zhineng Chen , Shuai Zhao , Hongtao Xie , Wenming Guo , Yongdong Zhang

Solving point-wise feature correspondence in visual data is a fundamental problem in computer vision. A powerful model that addresses this challenge is to formulate it as graph matching, which entails solving a Quadratic Assignment Problem…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Yongqing Liang , Huijun Han , Xin Li

Node2vec is a graph embedding method that learns a vector representation for each node of a weighted graph while seeking to preserve relative proximity and global structure. Numerical experiments suggest Node2vec struggles to recreate the…

Machine Learning · Statistics 2023-09-18 Yasuaki Hiraoka , Yusuke Imoto , Killian Meehan , Théo Lacombe , Toshiaki Yachimura

Positional encoding is essential for supplementing transformer with positional information of tokens. Existing positional encoding methods demand predefined token/feature order, rendering them unsuitable for real-world data with…

Machine Learning · Computer Science 2025-09-25 Kaichen Xu , Yihang Du , Mianpeng Liu , Zimu Yu , Xiaobo Sun

Conformal prediction (CP) transforms any model's output into prediction sets guaranteed to include (cover) the true label. CP requires exchangeability, a relaxation of the i.i.d. assumption, to obtain a valid distribution-free coverage…

Machine Learning · Computer Science 2024-07-15 Soroush H. Zargarbashi , Aleksandar Bojchevski

Image segmentation is critically important in almost all medical image analysis for automatic interpretations and processing. However, it is often challenging to perform image segmentation due to data imbalance between intra- and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Zhhengyong Huang , Yao Sui

Evaluating similarity between graphs is of major importance in several computer vision and pattern recognition problems, where graph representations are often used to model objects or interactions between elements. The choice of a distance…

Computer Vision and Pattern Recognition · Computer Science 2017-06-15 Sofia Ira Ktena , Sarah Parisot , Enzo Ferrante , Martin Rajchl , Matthew Lee , Ben Glocker , Daniel Rueckert

Traditional 2D pose estimation models are limited by their category-specific design, making them suitable only for predefined object categories. This restriction becomes particularly challenging when dealing with novel objects due to the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Or Hirschorn , Shai Avidan