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Significant advancements in AI-driven multimodal medical image diagnosis have led to substantial improvements in ophthalmic disease identification in recent years. However, acquiring paired multimodal ophthalmic images remains prohibitively…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Zhihao Zhao , Yinzheng Zhao , Junjie Yang , Xiangtong Yao , Quanmin Liang , Daniel Zapp , Kai Huang , Nassir Navab , M. Ali Nasseri

Myopia, projected to affect 50% population globally by 2050, is a leading cause of vision loss. Eyes with pathological myopia exhibit distinctive shape distributions, which are closely linked to the progression of vision-threatening…

Image and Video Processing · Electrical Eng. & Systems 2025-02-20 Danli Shi , Bowen Liu , Zhen Tian , Yue Wu , Jiancheng Yang , Ruoyu Chen , Bo Yang , Ou Xiao , Mingguang He

Diabetes is a globally prevalent disease that can cause visible microvascular complications such as diabetic retinopathy and macular edema in the human eye retina, the images of which are today used for manual disease screening. This…

Image and Video Processing · Electrical Eng. & Systems 2019-04-19 Jaakko Sahlsten , Joel Jaskari , Jyri Kivinen , Lauri Turunen , Esa Jaanio , Kustaa Hietala , Kimmo Kaski

A large number of different feature detectors has been proposed so far. Any existing approach presents strengths and weaknesses, which make a detector optimal only for a limited range of applications. A tool capable of selecting the optimal…

Computer Vision and Pattern Recognition · Computer Science 2016-05-20 Bruno Ferrarini , Shoaib Ehsan , Naveed Ur Rehman , Ales Leonardis , Klaus D. McDonald-Maier

In the last decades, large datasets of fundus photographs have been collected in diabetic retinopathy (DR) screening networks. Through deep learning, these datasets were used to train automatic detectors for DR and a few other frequent…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Gwenolé Quellec , Mathieu Lamard , Pierre-Henri Conze , Pascale Massin , Béatrice Cochener

The hemorrhagic lesion segmentation plays a critical role in ophthalmic diagnosis, directly influencing early disease detection, treatment planning, and therapeutic efficacy evaluation. However, the task faces significant challenges due to…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Zesheng Li , Minwen Liao , Haoran Chen , Yan Su , Chengchang Pan , Honggang Qi

Significance: Access to diagnostic eye care could be expanded with high-throughput and easy-to-use tools. Phase mask-based imaging may improve the fundus camera by enabling computational refocusing with no moving parts. While phase…

Papilledema is an ophthalmic neurologic disorder in which increased intracranial pressure leads to swelling of the optic nerves. Undiagnosed papilledema in children may lead to blindness and may be a sign of life-threatening conditions,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Kleanthis Avramidis , Mohammad Rostami , Melinda Chang , Shrikanth Narayanan

For decades, advances in retinal imaging technology have enabled effective diagnosis and management of retinal disease using fundus cameras. Recently, ultra-wide-field (UWF) fundus imaging by Optos camera is gradually put into use because…

Image and Video Processing · Electrical Eng. & Systems 2020-03-25 Lie Ju , Xin Wang , Quan Zhou , Hu Zhu , Mehrtash Harandi , Paul Bonnington , Tom Drummond , Zongyuan Ge

Fundus photography has routinely been used to document the presence and severity of retinal degenerative diseases such as age-related macular degeneration (AMD), glaucoma, and diabetic retinopathy (DR) in clinical practice, for which the…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Shuyun Tang , Ziming Qi , Jacob Granley , Michael Beyeler

Glaucoma is the leading cause of irreversible but preventable blindness in the world. Its major treatable risk factor is the intra-ocular pressure, although other biomarkers are being explored to improve the understanding of the…

Computer Vision and Pattern Recognition · Computer Science 2018-10-26 José Ignacio Orlando , João Barbosa Breda , Karel van Keer , Matthew B. Blaschko , Pablo J. Blanco , Carlos A. Bulant

Visual Question and Answering (VQA) problems are attracting increasing interest from multiple research disciplines. Solving VQA problems requires techniques from both computer vision for understanding the visual contents of a presented…

Computer Vision and Pattern Recognition · Computer Science 2016-04-07 Ilija Ilievski , Shuicheng Yan , Jiashi Feng

Recently, ultra-widefield (UWF) 200\degree~fundus imaging by Optos cameras has gradually been introduced because of its broader insights for detecting more information on the fundus than regular 30 degree - 60 degree fundus cameras.…

Computer Vision and Pattern Recognition · Computer Science 2021-02-03 Lie Ju , Xin Wang , Xin Zhao , Paul Bonnington , Tom Drummond , Zongyuan Ge

Purpose To develop a computer based method for the automated assessment of image quality in the context of diabetic retinopathy (DR) to guide the photographer. Methods A deep learning framework was trained to grade the images automatically.…

Computer Vision and Pattern Recognition · Computer Science 2017-03-08 Sajib Kumar Saha , Basura Fernando , Jorge Cuadros , Di Xiao , Yogesan Kanagasingam

High resolution is crucial for precise segmentation in fundus images, yet handling high-resolution inputs incurs considerable GPU memory costs, with diminishing performance gains as overhead increases. To address this issue while tackling…

Computer Vision and Pattern Recognition · Computer Science 2025-04-14 Ziyuan Ding , Yixiong Liang , Shichao Kan , Qing Liu

Purpose: This study introduces the first adaptation of RETFound for joint optic disc (OD) and optic cup (OC) segmentation. RETFound is a well-known foundation model developed for fundus camera and optical coherence tomography images, which…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Zhenyi Zhao , Muthu Rama Krishnan Mookiah , Emanuele Trucco

Over the past decade, generative models have achieved significant success in enhancement fundus images.However, the evaluation of these models still presents a considerable challenge. A comprehensive evaluation benchmark for fundus image…

Image and Video Processing · Electrical Eng. & Systems 2025-02-21 Wenhui Zhu , Xuanzhao Dong , Xin Li , Yujian Xiong , Xiwen Chen , Peijie Qiu , Vamsi Krishna Vasa , Zhangsihao Yang , Yi Su , Oana Dumitrascu , Yalin Wang

Glaucoma is a complex group of eye diseases marked by optic nerve damage, commonly linked to elevated intraocular pressure and biomarkers like retinal nerve fiber layer thickness. Understanding how these biomarkers interact is crucial for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-24 Cheng Huang , Weizheng Xie , Tsengdar Lee , Karanjit Kooner , Ning Zhang , Jia Zhang

For accurate glaucoma diagnosis and monitoring, reliable retinal layer segmentation in OCT images is essential. However, existing 2D segmentation methods often suffer from slice-to-slice inconsistencies due to the lack of contextual…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Hyunwoo Kim , Heesuk Kim , Wungrak Choi , Jae-Sang Hyun

In light of the expanding population, an automated framework of disease detection can assist doctors in the diagnosis of ocular diseases, yields accurate, stable, rapid outcomes, and improves the success rate of early detection. The work…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Md. Aiyub Ali , Md. Shakhawat Hossain , Md. Kawar Hossain , Subhadra Soumi Sikder , Sharun Akter Khushbu , Mirajul Islam