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Related papers: Digital Twins in Biopharmaceutical Manufacturing: …

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The potential of digital twin technology is yet to be fully realized due to its diversity and untapped potential. Digital twins enable systems' analysis, design, optimization, and evolution to be performed digitally or in conjunction with a…

Cryptography and Security · Computer Science 2024-07-23 MohammadHossein Homaei , Oscar Mogollon Gutierrez , Jose Carlos Sancho Nunez , Mar Avila Vegas , Andres Caro Lindo

The recent advancement of information and communication technology makes digitalisation of an entire manufacturing shop-floor possible where physical processes are tightly intertwined with their cyber counterparts. This led to an emergence…

Software Engineering · Computer Science 2021-02-08 Heejong Park , Arvind Easwaran , Sidharta Andalam

This paper explores the opportunities of using a digital twin to address the complexities of collaborative production systems through an industrial case and a demonstrator. A digital twin, as a virtual counterpart of a physical human-robot…

Computers and Society · Computer Science 2020-11-24 Ali Ahmad Malik , Alexander Brem

In the way towards Industry 4.0, the complexity of the industrial systems increases due to the presence of multiple agents, Cyber-Physical Systems, distributed sensing, and big data introducing unknown dynamics that affect the production…

Signal Processing · Electrical Eng. & Systems 2020-07-09 Jairo Viola , YangQuan Chen

Digital twins promise a better understanding and use of complex systems. To this end, they represent these systems at their runtime and may interact with them to control their processes. Software engineering is a wicked challenge in which…

Software Engineering · Computer Science 2025-10-08 Robin Kimmel , Judith Michael , Andreas Wortmann , Jingxi Zhang

The digital twin has emerged as a technology to predict the undesirables, and ensure desired performance of complex systems. Although digital twins have got attention in the manufacturing research spectrum, yet their industrial application…

Systems and Control · Electrical Eng. & Systems 2021-04-08 Ali Ahmad Malik

Emerging from NASA's spacecraft simulations in the 1960s, digital twin technology has advanced through industrial adoption to spark a healthcare transformation. A digital twin is a dynamic, data-driven virtual counterpart of a physical…

Artificial Intelligence · Computer Science 2025-11-27 Yunqi Zhang , Kuangyu Shi , Biao Li

Artificial Intelligence (AI) and Large Language Models (LLMs) hold significant promise in revolutionizing healthcare, especially in clinical applications. Simultaneously, Digital Twin technology, which models and simulates complex systems,…

Artificial Intelligence · Computer Science 2024-09-27 Himanshu Pandey , Akhil Amod , Shivang , Kshitij Jaggi , Ruchi Garg , Abheet Jain , Vinayak Tantia

In Industry 4.0, the digital twin is one of the emerging technologies, offering simulation abilities to predict, refine, and interpret conditions and operations, where it is crucial to emphasize a heightened concentration on the associated…

Systems and Control · Electrical Eng. & Systems 2024-12-19 Alexander D. Zemskov , Yao Fu , Runchao Li , Xufei Wang , Vispi Karkaria , Ying-Kuan Tsai , Wei Chen , Jianjing Zhang , Robert Gao , Jian Cao , Kenneth A. Loparo , Pan Li

Digital Twin technology is being envisioned to be an integral part of the industrial evolution in modern generation. With the rapid advancement in the Internet-of-Things (IoT) technology and increasing trend of automation, integration…

Robotics · Computer Science 2022-09-27 Sabur Baidya , Sumit K. Das , Mohammad Helal Uddin , Chase Kosek , Chris Summers

Future manufacturing requires complex systems that connect simulation platforms and virtualization with physical data from industrial processes. Digital twins incorporate a physical twin, a digital twin, and the connection between the two.…

Machine Learning · Computer Science 2021-09-20 Trier Mortlock , Deepan Muthirayan , Shih-Yuan Yu , Pramod P. Khargonekar , Mohammad A. Al Faruque

Recent technological advances have expanded the availability of high-throughput biological datasets, enabling the reliable design of digital twins of biomedical systems or patients. Such computational tools represent key reaction networks…

Quantitative Methods · Quantitative Biology 2025-09-03 Clémence Métayer , Annabelle Ballesta , Julien Martinelli

The collaboration between humans and robots re-quires a paradigm shift not only in robot perception, reasoning, and action, but also in the design of the robotic cell. This paper proposes an optimization framework for designing…

Robotics · Computer Science 2024-10-21 Christian Cella , Marco Faroni , Andrea Zanchettin , Paolo Rocco

We live in a world of exploding complexity driven by technical evolution as well as highly volatile socio-economic environments. Managing complexity is a key issue in everyday decision making such as providing safe, sustainable, and…

Computers and Society · Computer Science 2023-11-28 Dirk Hartmann

As collaborative robot (Cobot) adoption in many sectors grows, so does the interest in integrating digital twins in human-robot collaboration (HRC). Virtual representations of physical systems (PT) and assets, known as digital twins, can…

Robotics · Computer Science 2023-11-07 Mohamad Shaaban , Alessandro Carfì , Fulvio Mastrogiovanni

Although digital twins have recently emerged as a clear alternative for reliable asset representations, most of the solutions and tools available for the development of digital twins are tailored to specific environments. Furthermore,…

Software Engineering · Computer Science 2023-01-16 Julia Robles , Cristian Martín , Manuel Díaz

Digital Twin technology is an emerging concept that has become the centre of attention for industry and, in more recent years, academia. The advancements in industry 4.0 concepts have facilitated its growth, particularly in the…

Computers and Society · Computer Science 2020-06-19 Aidan Fuller , Zhong Fan , Charles Day , Chris Barlow

With many advancements in in silico biology in recent years, the paramount challenge is to translate the accumulated knowledge into exciting industry partnerships and clinical applications. Achieving models that characterize the link of…

Quantitative Methods · Quantitative Biology 2023-06-06 Michael Taynnan Barros , Michelangelo Paci , Aapo Tervonen , Elisa Passini , Jussi Koivumäki , Jari Hyttinen , Kerstin Lenk

Digital twin (DT) enables smart manufacturing by leveraging real-time data, AI models, and intelligent control systems. This paper presents a state-of-the-art analysis on the emerging field of DTs in the context of milling. The critical…

Systems and Control · Electrical Eng. & Systems 2025-12-16 Wenyi Liu , R. Sharma , W. "Grace" Guo , J. Yi , Y. B. Guo

The design and operation of systems are conventionally viewed as a sequential decision-making process that is informed by data from physical experiments and simulations. However, the integration of these high-dimensional and heterogeneous…

Applications · Statistics 2025-03-04 Anton van Beek , Vispi Karkaria , Wei Chen
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