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Pacreatic ductal adenocarcinoma (PDAC) remains one of the most lethal forms of cancer, with a five-year survival rate below 10% primarily due to late detection. This research develops and validates a deep learning framework for early PDAC…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Dennis Slobodzian , Amir Kordijazi

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer in which the tumor-vascular involvement greatly affects the resectability and, thus, overall survival of patients. However, current prognostic prediction methods fail to…

Image and Video Processing · Electrical Eng. & Systems 2023-09-14 Hexin Dong , Jiawen Yao , Yuxing Tang , Mingze Yuan , Yingda Xia , Jian Zhou , Hong Lu , Jingren Zhou , Bin Dong , Le Lu , Li Zhang , Zaiyi Liu , Yu Shi , Ling Zhang

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers and carries a dismal prognosis. Surgery remains the best chance of a potential cure for patients who are eligible for initial resection of PDAC. However, outcomes…

Image and Video Processing · Electrical Eng. & Systems 2020-08-28 Jiawen Yao , Yu Shi , Le Lu , Jing Xiao , Ling Zhang

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, and early detection remains a major clinical challenge due to the absence of specific symptoms and reliable biomarkers. In this work, we propose a new multimodal…

Early detection improves prognosis in pancreatic ductal adenocarcinoma (PDAC) but is challenging as lesions are often small and poorly defined on contrast-enhanced computed tomography scans (CE-CT). Deep learning can facilitate PDAC…

Image and Video Processing · Electrical Eng. & Systems 2022-01-14 Natália Alves , Megan Schuurmans , Geke Litjens , Joeran S. Bosma , John Hermans , Henkjan Huisman

Pancreatic cancer is one of the global leading causes of cancer-related deaths. Despite the success of Deep Learning in computer-aided diagnosis and detection (CAD) methods, little attention has been paid to the detection of Pancreatic…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Christiaan G. A. Viviers , Mark Ramaekers , Peter H. N. de With , Dimitrios Mavroeidis , Joost Nederend , Misha Luyer , Fons van der Sommen

As an analytic pipeline for quantitative imaging feature extraction and analysis, radiomics has grown rapidly in the past a few years. Recent studies in radiomics aim to investigate the relationship between tumors imaging features and…

Quantitative Methods · Quantitative Biology 2019-07-11 Yucheng Zhang , Edrise M. Lobo-Mueller , Paul Karanicolas , Steven Gallinger , Masoom A. Haider , Farzad Khalvati

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive forms of pancreatic cancer and is often diagnosed at an advanced stage due to subtle early imaging signs. To enable earlier detection and improve clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Han Liu , Riqiang Gao , Eileen Krieg , Sasa Grbic

The lethal nature of pancreatic ductal adenocarcinoma (PDAC) calls for early differential diagnosis of pancreatic cysts, which are identified in up to 16% of normal subjects, and some of which may develop into PDAC. Previous computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2018-06-20 Hongwei Li , Kanru Lin , Maximilian Reichert , Lina Xu , Rickmer Braren , Deliang Fu , Roland Schmid , Ji Li , Bjoern Menze , Kuangyu Shi

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with limited treatment options. This research proposes a workflow and deep learning-based segmentation models to automatically assess tumor-vessel involvement, a key…

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers among the population. Screening for PDACs in dynamic contrast-enhanced CT is beneficial for early diagnosis. In this paper, we investigate the problem of automated…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Yingda Xia , Qihang Yu , Wei Shen , Yuyin Zhou , Elliot K. Fishman , Alan L. Yuille

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers with an overall five-year survival rate of 8%. Due to subtle texture changes of PDAC, pancreatic dual-phase imaging is recommended for better diagnosis of pancreatic…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Yuyin Zhou , Yingwei Li , Zhishuai Zhang , Yan Wang , Angtian Wang , Elliot Fishman , Alan Yuille , Seyoun Park

We propose an intuitive approach of detecting pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer, by checking abdominal CT scans. Our idea is named multi-scale segmentation-for-classification, which…

Computer Vision and Pattern Recognition · Computer Science 2019-08-09 Zhuotun Zhu , Yingda Xia , Lingxi Xie , Elliot K. Fishman , Alan L. Yuille

The prediction of pancreatic ductal adenocarcinoma therapy response is a clinically challenging and important task in this high-mortality tumour entity. The training of neural networks able to tackle this challenge is impeded by a lack of…

Image and Video Processing · Electrical Eng. & Systems 2023-03-31 Alexander Ziller , Ayhan Can Erdur , Friederike Jungmann , Daniel Rueckert , Rickmer Braren , Georgios Kaissis

Accurate and automated tumor segmentation is highly desired since it has the great potential to increase the efficiency and reproducibility of computing more complete tumor measurements and imaging biomarkers, comparing to (often partial)…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Ling Zhang , Yu Shi , Jiawen Yao , Yun Bian , Kai Cao , Dakai Jin , Jing Xiao , Le Lu

We aim to detect pancreatic ductal adenocarcinoma (PDAC) in abdominal CT scans, which sheds light on early diagnosis of pancreatic cancer. This is a 3D volume classification task with little training data. We propose a two-stage framework,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-22 Fengze Liu , Lingxi Xie , Yingda Xia , Elliot K. Fishman , Alan L. Yuille

Pancreatic ductal adenocarcinoma (PDAC) presents a critical global health challenge, and early detection is crucial for improving the 5-year survival rate. Recent medical imaging and computational algorithm advances offer potential…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Yu Shi , Hannah Tang , Michael Baine , Michael A. Hollingsworth , Huijing Du , Dandan Zheng , Chi Zhang , Hongfeng Yu

Gastric cancer and Colon adenocarcinoma represent widespread and challenging malignancies with high mortality rates and complex treatment landscapes. In response to the critical need for accurate prognosis in cancer patients, the medical…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Xu Yan , Weimin Wang , MingXuan Xiao , Yufeng Li , Min Gao

Radiomics and deep learning both offer powerful tools for quantitative medical imaging, but most existing fusion approaches only leverage global radiomic features and overlook the complementary value of spatially resolved radiomic…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Zengtian Deng , Yimeng He , Yu Shi , Lixia Wang , Touseef Ahmad Qureshi , Xiuzhen Huang , Debiao Li

Pancreatic ductal adenocarcinoma (PDAC), one of the deadliest solid malignancies, is often detected at a late and inoperable stage. Retrospective reviews of prediagnostic CT scans, when conducted by expert radiologists aware that the…

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