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There is effect modification if the magnitude or stability of a treatment effect varies systematically with the level of an observed covariate. A larger or more stable treatment effect is typically less sensitive to bias from unmeasured…

Applications · Statistics 2016-12-12 Kwonsang Lee , Dylan S. Small , Jesse Y. Hsu , Jeffrey H. Silber , Paul R. Rosenbaum

Healthcare data continues to flourish yet a relatively small portion, mostly structured, is being utilized effectively for predicting clinical outcomes. The rich subjective information available in unstructured clinical notes can possibly…

Machine Learning · Computer Science 2019-11-20 Mohammad Hashir , Rapinder Sawhney

Obtaining datasets labeled to facilitate model development is a challenge for most machine learning tasks. The difficulty is heightened for medical imaging, where data itself is limited in accessibility and labeling requires costly time and…

Computation and Language · Computer Science 2018-10-03 Nithya Attaluri , Ahmed Nasir , Carolynne Powe , Harold Racz , Ben Covington , Li Yao , Jordan Prosky , Eric Poblenz , Tobi Olatunji , Kevin Lyman

The objective of this study is to develop a robust deep learning-based framework to distinguish COVID-19, Community-Acquired Pneumonia (CAP), and Normal cases based on chest CT scans acquired in different imaging centers using various…

Automatic ICD coding is the task of assigning codes from the International Classification of Diseases (ICD) to medical notes. These codes describe the state of the patient and have multiple applications, e.g., computer-assisted diagnosis or…

Computation and Language · Computer Science 2021-04-15 Damian Pascual , Sandro Luck , Roger Wattenhofer

We consider real-time timely tracking of infection status (e.g., covid-19) of individuals in a population. In this work, a health care provider wants to detect infected people as well as people who have recovered from the disease as quickly…

Information Theory · Computer Science 2022-06-15 Melih Bastopcu , Sennur Ulukus

Background: Chest computed tomography (CT) is recognized as an important tool for COVID-19 severity assessment. As the number of affected patients increase rapidly, manual severity assessment becomes a labor-intensive task, and may lead to…

Image and Video Processing · Electrical Eng. & Systems 2020-03-28 Zhenyu Tang , Wei Zhao , Xingzhi Xie , Zheng Zhong , Feng Shi , Jun Liu , Dinggang Shen

Background Predicting mortality and resource utilization from electronic health records (EHRs) is challenging yet crucial for optimizing patient outcomes and managing costs in intensive care unit (ICU). Existing approaches predominantly…

Computation and Language · Computer Science 2025-08-29 Yucheng Ruan , Xiang Lan , Daniel J. Tan , Hairil Rizal Abdullah , Mengling Feng

International Classification of Diseases (ICD) coding plays an important role in systematically classifying morbidity and mortality data. In this study, we propose a hierarchical label-wise attention Transformer model (HiLAT) for the…

Machine Learning · Computer Science 2022-10-04 Leibo Liu , Oscar Perez-Concha , Anthony Nguyen , Vicki Bennett , Louisa Jorm

Estimating the prevalence of a medical condition, or the proportion of the population in which it occurs, is a fundamental problem in healthcare and public health. Accurate estimates of the relative prevalence across groups -- capturing,…

Computers and Society · Computer Science 2023-12-13 Divya Shanmugam , Kaihua Hou , Emma Pierson

ICD(International Classification of Diseases) coding involves assigning ICD codes to patients visit based on their medical notes. Considering ICD coding as a multi-label text classification task, researchers have developed sophisticated…

Computation and Language · Computer Science 2024-10-21 Bin Zhang , Junli Wang

Objective: To develop a rule-based algorithm that detects temporal information of clinical events during pregnancy for women with COVID-19 by inferring gestational weeks and delivery dates from Electronic Health Records (EHR) from the…

Applications · Statistics 2023-01-11 Tianchu Lyu , Chen Liang , Jihong Liu , Berry Campbell , Peiyin Hung , Yi-Wen Shih , Nadia Ghumman , Xiaoming Li

Purpose: Artificial intelligence (AI) techniques have been extensively utilized for diagnosing and prognosis of several diseases in recent years. This study identifies, appraises and synthesizes published studies on the use of AI for the…

Healthcare data in the United States often records only a patient's coarse race group: for example, both Indian and Chinese patients are typically coded as "Asian." It is unknown, however, whether this coarse coding conceals meaningful…

Computers and Society · Computer Science 2023-08-28 Rajiv Movva , Divya Shanmugam , Kaihua Hou , Priya Pathak , John Guttag , Nikhil Garg , Emma Pierson

ICD coding from electronic clinical records is a manual, time-consuming and expensive process. Code assignment is, however, an important task for billing purposes and database organization. While many works have studied the problem of…

Computation and Language · Computer Science 2020-11-18 Arthur D. Reys , Danilo Silva , Daniel Severo , Saulo Pedro , Marcia M. de Souza e Sá , Guilherme A. C. Salgado

Data accuracy is essential for scientific research and policy development. The National Violent Death Reporting System (NVDRS) data is widely used for discovering the patterns and causes of death. Recent studies suggested the annotation…

Computation and Language · Computer Science 2024-04-01 Song Wang , Yiliang Zhou , Ziqiang Han , Cui Tao , Yunyu Xiao , Ying Ding , Joydeep Ghosh , Yifan Peng

In this paper, we discuss the impact of some mortality data anomalies on an internal model capturing longevity risk in the Solvency 2 framework. In particular, we are concerned with abnormal cohort effects such as those for generations 1919…

Risk Management · Quantitative Finance 2020-09-02 Fabrice Balland , Alexandre Boumezoued , Laurent Devineau , Marine Habart , Tom Popa

Despite the potential of weakly supervised learning to automatically annotate massive amounts of data, little is known about its limitations for use in computer-aided diagnosis (CAD). For CT specifically, interpreting the performance of CAD…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Fakrul Islam Tushar , Vincent M. D'Anniballe , Geoffrey D. Rubin , Ehsan Samei , Joseph Y. Lo

In medical coding, experts map unstructured clinical notes to alphanumeric codes for diagnoses and procedures. We introduce Code Like Humans: a new agentic framework for medical coding with large language models. It implements official…

Artificial Intelligence · Computer Science 2025-10-09 Andreas Motzfeldt , Joakim Edin , Casper L. Christensen , Christian Hardmeier , Lars Maaløe , Anna Rogers

Background: Stroke is second-leading cause of disability and death among adults. Approximately 17 million people suffer from a stroke annually, with about 85% being ischemic strokes. Predicting mortality of ischemic stroke patients in…

Machine Learning · Computer Science 2024-09-04 Armin Abdollahi , Negin Ashrafi , Maryam Pishgar