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Microfluidic Live-Cell Imaging (MLCI) generates high-quality data that allows biotechnologists to study cellular growth dynamics in detail. However, obtaining these continuous data over extended periods is challenging, particularly in…

High-speed autofocus in extreme scenes remains a significant challenge. Traditional methods rely on repeated sampling around the focus position, resulting in ``focus hunting''. Event-driven methods have advanced focusing speed and improved…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Yuhan Bao , Shaohua Gao , Wenyong Li , Kaiwei Wang

In the biomedical environment, experiments assessing dynamic processes are primarily performed by a human acquisition supervisor. Contemporary implementations of such experiments frequently aim to acquire a maximum number of relevant events…

Computer Vision and Pattern Recognition · Computer Science 2023-10-10 Nils Friederich , Angelo Yamachui Sitcheu , Oliver Neumann , Süheyla Eroğlu-Kayıkçı , Roshan Prizak , Lennart Hilbert , Ralf Mikut

Purpose: To introduce a combined machine learning (ML) and physics-based image reconstruction framework that enables navigator-free, highly accelerated multishot echo planar imaging (msEPI), and demonstrate its application in…

Event cameras detect changes in per-pixel intensity to generate asynchronous `event streams'. They offer great potential for accurate semantic map retrieval in real-time autonomous systems owing to their much higher temporal resolution and…

Computer Vision and Pattern Recognition · Computer Science 2023-09-29 Shristi Das Biswas , Adarsh Kosta , Chamika Liyanagedera , Marco Apolinario , Kaushik Roy

The Auto-ICell system, a novel, and cost-effective integrated droplet microfluidic system, is introduced for real-time analysis of single-cell morphology and apoptosis. This system integrates a 3D-printed microfluidic chip with image…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Yuanyuan Wei , Meiai Lin , Shanhang Luo , Syed Muhammad Tariq Abbasi , Liwei Tan , Guangyao Cheng , Bijie Bai , Yi-Ping Ho , Scott Wu Yuan , Ho-Pui Ho

The increasing data rates in modern high-energy physics experiments such as ALICE at the LHC and the upcoming ePIC experiment at the Electron-Ion Collider (EIC) present significant challenges in real-time event selection and data storage.…

High Energy Physics - Experiment · Physics 2025-06-24 Simone Ragoni , Janet Seger , Christopher Anson , David Tlusty

Motivation: Innovative microfluidic systems carry the promise to greatly facilitate spatio-temporal analysis of single cells under well-defined environmental conditions, allowing novel insights into population heterogeneity and opening new…

Machine Learning · Computer Science 2021-05-18 Dominik Stallmann , Jan P. Göpfert , Julian Schmitz , Alexander Grünberger , Barbara Hammer

Sepsis is a life threatening condition that requires timely detection in intensive care settings. Traditional machine learning approaches, including Naive Bayes, Support Vector Machine (SVM), Random Forest, and XGBoost, often rely on manual…

Machine Learning · Computer Science 2025-09-03 Hejiang Cai , Di Wu , Ji Xu , Xiang Liu , Yiziting Zhu , Xin Shu , Yujie Li , Bin Yi

Automated in-vitro cell detection and counting have been a key theme for artificial and intelligent biological analysis such as biopsy, drug analysis and decease diagnosis. Along with the rapid development of microfluidics and lab-on-chip…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Tiancheng Xia , Richard Jiang , YongQing Fu , Nanlin Jin

Panoptic segmentation, combining semantic and instance segmentation, stands as a cutting-edge computer vision task. Despite recent progress with deep learning models, the dynamic nature of real-world applications necessitates continual…

Computer Vision and Pattern Recognition · Computer Science 2024-04-01 Beomyoung Kim , Joonsang Yu , Sung Ju Hwang

Objective. Reliable, continuous neural sensing on wearable edge platforms is fundamental to long-term health monitoring; however, for electroencephalography (EEG)-based sleep monitoring, dense high-frequency processing is often…

Signal Processing · Electrical Eng. & Systems 2026-02-24 Boyu Li , Xingchun Zhu , Yonghui Wu

Live-cell imaging (LCI) technology enables the detailed spatio-temporal characterization of living cells at the single-cell level, which is critical for advancing research in the life sciences, from biomedical applications to bioprocessing.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Johannes Seiffarth , Keitaro Kasahara , Michelle Bund , Benita Lückel , Richard D. Paul , Matthias Pesch , Lennart Witting , Michael Bott , Dietrich Kohlheyer , Katharina Nöh

Recent visual autonomous perception systems achieve remarkable performances with deep representation learning. However, they fail in scenarios with challenging illumination.While event cameras can mitigate this problem, there is a lack of a…

Robotics · Computer Science 2026-03-18 Jinghang Li , Shichao Li , Qing Lian , Peiliang Li , Xiaozhi Chen , Yi Zhou

Although deep learning (DL) shows powerful potential in cell segmentation tasks, it suffers from poor generalization as DL-based methods originally simplified cell segmentation in detecting cell membrane boundary, lacking prominent cellular…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Fang Hu , Xuexue Sun , Ke Qing , Fenxi Xiao , Zhi Wang , Xiaolu Fan

Cell segmentation is a fundamental task for computational biology analysis. Identifying the cell instances is often the first step in various downstream biomedical studies. However, many cell segmentation algorithms, including the recently…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Gihun Lee , Sangmook Kim , Joonkee Kim , Se-Young Yun

We present an active learning framework for efficiently generating training data for machine-learned interatomic potentials (MLIPs). The method combines local entropy-driven molecular dynamics with global dataset-aware filtering: a…

Materials Science · Physics 2026-05-21 Meiyan Wang , Rishi Rao , Li Zhu

Live-cell imaging of multiple subcellular structures is essential for understanding subcellular dynamics. However, the conventional multi-color sequential fluorescence microscopy suffers from significant imaging delays and limited number of…

Subcellular Processes · Quantitative Biology 2025-01-13 Mingyang Chen , Luhong Jin , Xuwei Xuan , Defu Yang , Yun Cheng , Ju Zhang

Single-beam scanning electron microscopes (SEM) are widely used to acquire massive data sets for biomedical study, material analysis, and fabrication inspection. Datasets are typically acquired with uniform acquisition: applying the…

Image and Video Processing · Electrical Eng. & Systems 2021-01-11 Lu Mi , Hao Wang , Yaron Meirovitch , Richard Schalek , Srinivas C. Turaga , Jeff W. Lichtman , Aravinthan D. T. Samuel , Nir Shavit

An event camera is a novel vision sensor that can capture per-pixel brightness changes and output a stream of asynchronous ``events''. It has advantages over conventional cameras in those scenes with high-speed motions and challenging…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Junyu Zhu , Lina Liu , Bofeng Jiang , Feng Wen , Hongbo Zhang , Wanlong Li , Yong Liu
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