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Identifying disease interconnections through manual analysis of large-scale clinical data is labor-intensive, subjective, and prone to expert disagreement. While machine learning (ML) shows promise, three critical challenges remain: (1)…

Precise estimation of cardiac patients' current and future comorbidities is an important factor in prioritizing continuous physiological monitoring and new therapies. ML models have shown satisfactory performance in short-term mortality…

Machine Learning · Computer Science 2024-03-05 Bijan Roudini , Boshra Khajehpiri , Hamid Abrishami Moghaddam , Mohamad Forouzanfar

Birth weight serves as a fundamental indicator of neonatal health, closely linked to both early medical interventions and long-term developmental risks. Traditional predictive models, often constrained by limited feature selection and…

The integration of Artificial Intelligence (AI) and the Internet of Medical Things (IoMT) in healthcare, through Machine Learning (ML) and Deep Learning (DL) techniques, has advanced the prediction and diagnosis of chronic diseases.…

Machine Learning · Computer Science 2024-10-02 Akeem Temitope Otapo , Alice Othmani , Ghazaleh Khodabandelou , Zuheng Ming

In biomedical applications of machine learning, relevant information often has a rich structure that is not easily encoded as real-valued predictors. Examples of such data include DNA or RNA sequences, gene sets or pathways, gene…

Genomics · Quantitative Biology 2019-10-16 Jake Crawford , Casey S. Greene

High-quality data accumulation is now becoming ubiquitous in the health domain. There is increasing opportunity to exploit rich data from normal subjects to improve supervised estimators in specific diseases with notorious data scarcity. We…

Machine Learning · Computer Science 2021-10-13 Marc-Andre Schulz , Bertrand Thirion , Alexandre Gramfort , Gaël Varoquaux , Danilo Bzdok

Joint models for longitudinal and time-to-event data are commonly used in longitudinal studies to forecast disease trajectories over time. While there are many advantages to joint modeling, the standard forms suffer from limitations that…

Machine Learning · Statistics 2019-09-09 Bryan Lim , Mihaela van der Schaar

Individuals with suspected rare genetic disorders often undergo multiple clinical evaluations, imaging studies, laboratory tests and genetic tests, to find a possible answer over a prolonged period of time. Addressing this "diagnostic…

Age prediction using brain imaging, such as MRIs, has achieved promising results, with several studies identifying the model's residual as a potential biomarker for chronic disease states. In this study, we developed a brain age predictive…

Machine Learning · Computer Science 2025-04-22 Shahrzad Jamshidi , Arthur Bousquet , Sugata Banerji , Mark F. Conneely , Bita Aslrousta

Mobile phones and other electronic gadgets or devices have aided in collecting data without the need for data entry. This paper will specifically focus on Mobile health data. Mobile health data use mobile devices to gather clinical health…

Machine Learning · Computer Science 2023-04-27 Jonayet Miah , Muntasir Mamun , Md Minhazur Rahman , Md Ishtyaq Mahmud , Sabbir Ahmed , Md Hasan Bin Nasir

Metabolic (dysfunction) associated fatty liver disease (MAFLD) establishes new criteria for diagnosing fatty liver disease independent of alcohol consumption and concurrent viral hepatitis infection. However, the long-term outcome of MAFLD…

In this work we present a deep learning approach to conduct hypothesis-free, transcriptomics-based matching of drugs for diseases. Our proposed neural network architecture is trained on approved drug-disease indications, taking as input the…

Genomics · Quantitative Biology 2023-03-22 Yannis Papanikolaou , Francesco Tuveri , Misa Ogura , Daniel O'Donovan

Computer-aided detection has been a research area attracting great interest in the past decade. Machine learning algorithms have been utilized extensively for this application as they provide a valuable second opinion to the doctors.…

Large-scale medical studies such as the UK Biobank examine thousands of volunteer participants with medical imaging techniques. Combined with the vast amount of collected metadata, anatomical information from these images has the potential…

Image and Video Processing · Electrical Eng. & Systems 2021-05-18 Taro Langner , Robin Strand , Håkan Ahlström , Joel Kullberg

The recent development of imaging and sequencing technologies enables systematic advances in the clinical study of lung cancer. Meanwhile, the human mind is limited in effectively handling and fully utilizing the accumulation of such…

Machine Learning · Computer Science 2022-03-29 Yawei Li , Xin Wu , Ping Yang , Guoqian Jiang , Yuan Luo

Cardiac diseases are among the leading causes of morbidity and mortality worldwide, which requires accurate and timely diagnostic strategies. In this study, we introduce an innovative approach that combines deep learning image registration…

Machine Learning · Computer Science 2025-07-09 Comte Valentin , Gemma Piella , Mario Ceresa , Miguel A. Gonzalez Ballester

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models…

Machine Learning · Computer Science 2023-11-21 Alice Bernasconi , Alessio Zanga , Peter J. F. Lucas , Marco Scutari , Fabio Stella

Applying machine learning in the health care domain has shown promising results in recent years. Interpretable outputs from learning algorithms are desirable for decision making by health care personnel. In this work, we explore the…

Machine Learning · Computer Science 2017-11-30 Marcus Klasson , Kun Zhang , Bo C. Bertilson , Cheng Zhang , Hedvig Kjellström

Decision-making related to health is complex. Machine learning (ML) and patient generated data can identify patterns and insights at the individual level, where human cognition falls short, but not all ML-generated information is of equal…

Applications · Statistics 2021-01-15 Elliot G Mitchell , Esteban G Tabak , Matthew E Levine , Lena Mamykina , David J Albers

Background: Identification of the interactions and regulatory relations between biomolecules play pivotal roles in understanding complex biological systems and the mechanisms underlying diverse biological functions. However, the collection…

Computation and Language · Computer Science 2025-04-24 Gilchan Park , Byung-Jun Yoon , Xihaier Luo , Vanessa López-Marrero , Shinjae Yoo , Shantenu Jha