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Objective: To develop a natural language processing (NLP) system to extract medications and contextual information that help understand drug changes. This project is part of the 2022 n2c2 challenge. Materials and methods: We developed NLP…

Computation and Language · Computer Science 2023-05-10 Aokun Chen , Zehao Yu , Xi Yang , Yi Guo , Jiang Bian , Yonghui Wu

There is an increasing interest in developing artificial intelligence (AI) systems to process and interpret electronic health records (EHRs). Natural language processing (NLP) powered by pretrained language models is the key technology for…

Objective: To develop a natural language processing system that solves both clinical concept extraction and relation extraction in a unified prompt-based machine reading comprehension (MRC) architecture with good generalizability for…

Computation and Language · Computer Science 2023-07-07 Cheng Peng , Xi Yang , Zehao Yu , Jiang Bian , William R. Hogan , Yonghui Wu

Clinical notes contain an abundance of important but not-readily accessible information about patients. Systems to automatically extract this information rely on large amounts of training data for which their exists limited resources to…

Computation and Language · Computer Science 2020-04-23 Andriy Mulyar , Bridget T. McInnes

Clinical documentation can contain emotionally charged language with stigmatizing or privileging valences. We present a framework for detecting and classifying such language as stigmatizing, privileging, or neutral. We constructed a curated…

Delirium is an acute decline or fluctuation in attention, awareness, or other cognitive function that can lead to serious adverse outcomes. Despite the severe outcomes, delirium is frequently unrecognized and uncoded in patients' electronic…

Information extraction from conversational data is particularly challenging because the task-centric nature of conversation allows for effective communication of implicit information by humans, but is challenging for machines. The…

Computation and Language · Computer Science 2022-06-23 Sopan Khosla , Shikhar Vashishth , Jill Fain Lehman , Carolyn Rose

Multi-Task Learning (MTL) is widely-accepted in Natural Language Processing as a standard technique for learning multiple related tasks in one model. Training an MTL model requires having the training data for all tasks available at the…

Computation and Language · Computer Science 2023-02-23 Sudipta Kar , Giuseppe Castellucci , Simone Filice , Shervin Malmasi , Oleg Rokhlenko

Mobile health (mHealth) apps such as menstrual trackers provide a rich source of self-tracked health observations that can be leveraged for health-relevant research. However, such data streams have questionable reliability since they hinge…

Machine Learning · Computer Science 2021-03-18 Kathy Li , Iñigo Urteaga , Amanda Shea , Virginia J. Vitzthum , Chris H. Wiggins , Noémie Elhadad

Fine-tuning pre-trained language models (PLMs), e.g., SciBERT, generally requires large numbers of annotated data to achieve state-of-the-art performance on a range of NLP tasks in the scientific domain. However, obtaining the fine-tune…

Computation and Language · Computer Science 2025-12-30 Jiawei Liu , Zi Xiong , Yi Jiang , Yongqiang Ma , Wei Lu , Yong Huang , Qikai Cheng

The ultrasound characteristics of thyroid nodules guide the evaluation of thyroid cancer in patients with thyroid nodules. However, the characteristics of thyroid nodules are often documented in clinical narratives such as ultrasound…

Computation and Language · Computer Science 2023-04-04 Aman Pathak , Zehao Yu , Daniel Paredes , Elio Paul Monsour , Andrea Ortiz Rocha , Juan P. Brito , Naykky Singh Ospina , Yonghui Wu

Recent advancements in Large Language Models (LLMs) have played a significant role in reducing human workload across various domains, a trend that is increasingly extending into the medical field. In this paper, we propose an automated…

Computation and Language · Computer Science 2026-03-30 Kyomin Hwang , Nojun Kwak

Natural language processing (NLP) is a key technology to extract important patient information from clinical narratives to support healthcare applications. The rapid development of large language models (LLMs) has revolutionized many NLP…

Computation and Language · Computer Science 2025-09-08 Cheng Peng , Xinyu Dong , Mengxian Lyu , Daniel Paredes , Yaoyun Zhang , Yonghui Wu

Clinical notes in electronic health records contain highly heterogeneous writing styles, including non-standard terminology or abbreviations. Using these notes in predictive modeling has traditionally required preprocessing (e.g. taking…

Machine Learning · Computer Science 2019-11-18 Jonas Kemp , Alvin Rajkomar , Andrew M. Dai

This study aims to explore the performance improvement method of large language models based on GPT-4 under the multi-task learning framework and conducts experiments on two tasks: text classification and automatic summary generation.…

Computation and Language · Computer Science 2024-12-10 Zhen Qi , Jiajing Chen , Shuo Wang , Bingying Liu , Hongye Zheng , Chihang Wang

Objective To solve major clinical natural language processing (NLP) tasks using a unified text-to-text learning architecture based on a generative large language model (LLM) via prompt tuning. Methods We formulated 7 key clinical NLP tasks…

Computation and Language · Computer Science 2023-12-12 Cheng Peng , Xi Yang , Aokun Chen , Zehao Yu , Kaleb E Smith , Anthony B Costa , Mona G Flores , Jiang Bian , Yonghui Wu

In this paper, we introduce a novel task for machine learning in healthcare, namely personalized modeling of the female hormonal cycle. The motivation for this work is to model the hormonal cycle and predict its phases in time, both for…

Machine Learning · Statistics 2017-12-04 Iñigo Urteaga , David J. Albers , Marija Vlajic Wheeler , Anna Druet , Hans Raffauf , Noémie Elhadad

Retrieving and extracting knowledge from extensive research documents and large databases presents significant challenges for researchers, students, and professionals in today's information-rich era. Existing retrieval systems, which rely…

Information Retrieval · Computer Science 2025-02-06 Mohammed-Khalil Ghali , Abdelrahman Farrag , Daehan Won , Yu Jin

Symptom information is primarily documented in free-text clinical notes and is not directly accessible for downstream applications. To address this challenge, information extraction approaches that can handle clinical language variation…

Computation and Language · Computer Science 2023-02-27 Sitong Zhou , Kevin Lybarger , Meliha Yetisgen , Mari Ostendorf

The progress in natural language processing (NLP) using large language models (LLMs) has greatly improved patient information extraction from clinical narratives. However, most methods based on the fine-tuning strategy have limited transfer…

Computation and Language · Computer Science 2024-03-20 Cheng Peng , Zehao Yu , Kaleb E Smith , Wei-Hsuan Lo-Ciganic , Jiang Bian , Yonghui Wu
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