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We present a new approach for physics-based computational modeling of diseased human lungs. Our main object is the development of a model that takes the novel step of incorporating the dynamics of airway recruitment/de-recruitment into an…

Computational Engineering, Finance, and Science · Computer Science 2023-05-10 Carolin M. Geitner , Tobias Becher , Inéz Frerichs , Norbert Weiler , Jason H. T. Bates , Wolfgang A. Wall

Chest radiographs are primarily employed for the screening of pulmonary and cardio-/thoracic conditions. Being undertaken at primary healthcare centers, they require the presence of an on-premise reporting Radiologist, which is a challenge…

Computer Vision and Pattern Recognition · Computer Science 2020-04-27 Arka Mitra , Arunava Chakravarty , Nirmalya Ghosh , Tandra Sarkar , Ramanathan Sethuraman , Debdoot Sheet

Purpose: Analysis of [18F]-Fluorodeoxyglucose (FDG) kinetics in cancer has been most often limited to the evaluation of the average uptake over relatively large volumes. Nevertheless, tumor lesion almost contains inflammatory infiltrates…

Identifying image features that are robust with respect to segmentation variability and domain shift is a tough challenge in radiomics. So far, this problem has mainly been tackled in test-retest analyses. In this work we analyze radiomics…

Image and Video Processing · Electrical Eng. & Systems 2020-01-22 Christoph Haarburger , Justus Schock , Daniel Truhn , Philippe Weitz , Gustav Mueller-Franzes , Leon Weninger , Dorit Merhof

High-quality 3D reconstruction of pulmonary segments plays a crucial role in segmentectomy and surgical planning for the treatment of lung cancer. Due to the resolution requirement of the target reconstruction, conventional deep…

Graphics · Computer Science 2025-12-16 Kangxian Xie , Yufei Zhu , Kaiming Kuang , Li Zhang , Hongwei Bran Li , Mingchen Gao , Jiancheng Yang

One of the main challenges in times of sanitary emergency is to quickly develop computer aided diagnosis systems with a limited number of available samples due to the novelty, complexity of the case and the urgency of its implementation.…

Image and Video Processing · Electrical Eng. & Systems 2021-03-09 Plácido L Vidal , Joaquim de Moura , Jorge Novo , Marcos Ortega

High-resolution volumetric computed tomography (CT) is essential for accurate diagnosis and treatment planning in thoracic diseases; however, it is limited by radiation dose and hardware costs. We present the Transformer Volumetric…

Classical radiomic features have been designed to describe image appearance and intensity patterns. These features are directly interpretable and readily understood by radiologists. Compared with end-to-end deep learning (DL) models, lower…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Yaxi Chen , Simin Ni , Aleksandra Ivanova , Shaheer U. Saeed , Rikin Hargunani , Jie Huang , Chaozong Liu , Yipeng Hu

During the radiotherapy treatment of patients with lung cancer, the radiation delivered to healthy tissue around the tumor needs to be minimized, which is difficult because of respiratory motion and the latency of linear accelerator…

Image and Video Processing · Electrical Eng. & Systems 2022-07-14 Michel Pohl , Mitsuru Uesaka , Kazuyuki Demachi , Ritu Bhusal Chhatkuli

Before the recent success of deep learning methods for automated medical image analysis, practitioners used handcrafted radiomic features to quantitatively describe local patches of medical images. However, extracting discriminative…

Computer Vision and Pattern Recognition · Computer Science 2022-10-20 Yan Han , Gregory Holste , Ying Ding , Ahmed Tewfik , Yifan Peng , Zhangyang Wang

Reliable and automatic segmentation of lung lobes is important for diagnosis, assessment, and quantification of pulmonary diseases. The existing techniques are prohibitively slow, undesirably rely on prior (airway/vessel) segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-23 Abdullah-Al-Zubaer Imran , Ali Hatamizadeh , Shilpa P. Ananth , Xiaowei Ding , Demetri Terzopoulos , Nima Tajbakhsh

Automated segmentation of left ventricular cavity (LVC) in temporal cardiac image sequences (multiple time points) is a fundamental requirement for quantitative analysis of its structural and functional changes. Deep learning based methods…

Image and Video Processing · Electrical Eng. & Systems 2024-12-18 Yuyu Guo , Lei Bi , Zhengbin Zhu , David Dagan Feng , Ruiyan Zhang , Qian Wang , Jinman Kim

While the acute phase of the COVID-19 pandemic has subsided, its long-term effects persist through Post-Acute Sequelae of COVID-19 (PASC), commonly known as Long COVID. There remains substantial uncertainty regarding both its duration and…

Purpose: Respiratory gated radiation therapy (RGRT) is used to minimize the radiation dose to normal tissue in lung cancer patients. Determinations of the gating window in the respiratory phase of patients are important in RGRT but it is…

Medical Physics · Physics 2016-09-28 Se An Oh , Ji Woon Yea , Hyun Jeong Lee , Sung Kyu Kim

The paper proposes a novel hybrid discovery Radiomics framework that simultaneously integrates temporal and spatial features extracted from non-thin chest Computed Tomography (CT) slices to predict Lung Adenocarcinoma (LUAC) malignancy with…

Image and Video Processing · Electrical Eng. & Systems 2022-10-28 Sadaf Khademi , Shahin Heidarian , Parnian Afshar , Farnoosh Naderkhani , Anastasia Oikonomou , Konstantinos Plataniotis , Arash Mohammadi

Automated semantic image segmentation is an essential step in quantitative image analysis and disease diagnosis. This study investigates the performance of a deep learning-based model for lung segmentation from CT images for normal and…

Purpose: Radiotherapy presents unique challenges and clinical requirements for longitudinal tumor and organ-at-risk (OAR) prediction during treatment. The challenges include tumor inflammation/edema and radiation-induced changes in organ…

Computer Vision and Pattern Recognition · Computer Science 2021-09-01 Donghoon Lee , Sadegh R Alam , Jue Jiang , Pengpeng Zhang , Saad Nadeem , Yu-Chi Hu

Pulmonary lobe segmentation is an important task for pulmonary disease related Computer Aided Diagnosis systems (CADs). Classical methods for lobe segmentation rely on successful detection of fissures and other anatomical information such…

Computer Vision and Pattern Recognition · Computer Science 2019-04-11 Hao Tang , Chupeng Zhang , Xiaohui Xie

Lung cancer ranks as one of the leading causes of cancer diagnosis and is the foremost cause of cancer-related mortality worldwide. The early detection of lung nodules plays a pivotal role in improving outcomes for patients, as it enables…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Jiasen Zhang , Mingrui Yang , Weihong Guo , Brian A. Xavier , Michael Bolen , Xiaojuan Li

Automated segmentation of Lungs plays a crucial role in the computer-aided diagnosis of chest X-Ray (CXR) images. Developing an efficient Lung segmentation model is challenging because of difficulties such as the presence of several edges…

Computer Vision and Pattern Recognition · Computer Science 2018-12-03 Jyoti Islam , Yanqing Zhang
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