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With the rapid development of high-throughput sequencing platforms, an increasing number of omics technologies, such as genomics, metabolomics, and transcriptomics, are being applied to disease genetics research. However, biological data…

Genomics · Quantitative Biology 2024-12-18 Lei Xin , Caiyun Huang , Hao Li , Shihong Huang , Yuling Feng , Zhenglun Kong , Zicheng Liu , Siyuan Li , Chang Yu , Fei Shen , Hao Tang

In human-AI decision making, designing AI that complements human expertise has been a natural strategy to enhance human-AI collaboration, yet it often comes at the cost of decreased AI performance in areas of human strengths. This can…

Artificial Intelligence · Computer Science 2026-02-24 Hasan Amin , Ming Yin , Rajiv Khanna

Many complex discourse-level tasks can aid domain experts in their work but require costly expert annotations for data creation. To speed up and ease annotations, we investigate the viability of automatically generated annotation…

Background: Ontologies are fundamental components of informatics infrastructure in domains such as biomedical, environmental, and food sciences, representing consensus knowledge in an accurate and computable form. However, their…

Collaboration is the defining mode of modern science, yet its core mechanism -- feedback -- remains hard to observe, difficult to scale, and unequally distributed. Here we test whether large language models (LLMs) can contribute to this…

Physics and Society · Physics 2026-05-26 Binglu Wang , Weixin Liang , Jiahui Xue , Yuhui Zhang , Hancheng Cao , Dashun Wang , Yian Yin

The advancement of Document Intelligence (DI) demands large-scale, high-quality training data, yet manual annotation remains a critical bottleneck. While data generation methods are evolving rapidly, existing surveys are constrained by…

Artificial Intelligence · Computer Science 2026-01-21 Dehao Ying , Fengchang Yu , Haihua Chen , Changjiang Jiang , Yurong Li , Wei Lu

The growing availability of generative AI technologies such as large language models (LLMs) has significant implications for creative work. This paper explores twofold aspects of integrating LLMs into the creative process - the divergence…

Human-Computer Interaction · Computer Science 2024-03-04 Orit Shaer , Angelora Cooper , Osnat Mokryn , Andrew L. Kun , Hagit Ben Shoshan

Intelligent systems have traditionally been designed as tools rather than collaborators, often lacking critical characteristics that collaboration partnerships require. Recent advances in large language model (LLM) agents open new…

Human-Computer Interaction · Computer Science 2026-02-17 Bingsheng Yao , Jiaju Chen , Chaoran Chen , April Wang , Toby Jia-jun Li , Dakuo Wang

Modeling complex subjective tasks in Natural Language Processing, such as recognizing emotion and morality, is considerably challenging due to significant variation in human annotations. This variation often reflects reasonable differences…

Computation and Language · Computer Science 2025-11-12 Georgios Chochlakis , Peter Wu , Arjun Bedi , Marcus Ma , Kristina Lerman , Shrikanth Narayanan

Neuroscience data are highly fragmented across labs, formats, and experimental paradigms, and reuse often requires substantial manual effort. A persistent roadblock to data reuse and integration is the need to decipher bespoke and diverse…

Machine Learning · Computer Science 2026-05-15 Ling-Qi Zhang , Kristin Branson

Drug discovery is a complex process that involves sequentially screening and examining a vast array of molecules to identify those with the target properties. This process, also referred to as sequential experimentation, faces challenges…

Artificial Intelligence · Computer Science 2024-05-08 Jinghai He , Cheng Hua , Yingfei Wang , Zeyu Zheng

High-quality human annotations are necessary for creating effective machine learning-driven stream processing systems. We study hybrid stream processing systems based on a Human-In-The-Loop Machine Learning (HITL-ML) paradigm, in which one…

Human-Computer Interaction · Computer Science 2022-01-19 Rahul Pandey , Hemant Purohit , Carlos Castillo , Valerie L. Shalin

We investigate the ability of a genetic algorithm to design cellular automata that perform computations. The computational strategies of the resulting cellular automata can be understood using a framework in which ``particles'' embedded in…

adap-org · Physics 2015-06-30 James P. Crutchfield , Melanie Mitchell , Rajarshi Das

Automatic phenotype concept recognition from unstructured text remains a challenging task in biomedical text mining research. Previous works that address the task typically use dictionary-based matching methods, which can achieve high…

Computation and Language · Computer Science 2021-01-26 Ling Luo , Shankai Yan , Po-Ting Lai , Daniel Veltri , Andrew Oler , Sandhya Xirasagar , Rajarshi Ghosh , Morgan Similuk , Peter N. Robinson , Zhiyong Lu

As AI agents take on increasingly long-running tasks involving sophisticated planning and execution, there is a corresponding need for novel interaction designs that enable deeper human-agent collaboration. However, most prior works…

Human-Computer Interaction · Computer Science 2026-02-19 K. J. Kevin Feng , Kevin Pu , Matt Latzke , Tal August , Pao Siangliulue , Jonathan Bragg , Daniel S. Weld , Amy X. Zhang , Joseph Chee Chang

Artificial Intelligence (AI) is making a major impact on healthcare, particularly through its application in natural language processing (NLP) and predictive analytics. The healthcare sector has increasingly adopted AI for tasks such as…

Databases · Computer Science 2025-06-02 Karan Hanswadkar , Anika Kanchi , Shivani Tripathi , Shi Qiao , Rony Chatterjee , Alekh Jindal

Image collections, if critical aspects of image content are exposed, can spur research and practical applications in many domains. Supervised machine learning may be the only feasible way to annotate very large collections, but leading…

Computer Vision and Pattern Recognition · Computer Science 2019-03-01 Sara Mousavi , Ramin Nabati , Megan Kleeschulte , Audris Mockus

Neural approaches have become very popular in Question Answering (QA), however, they require a large amount of annotated data. In this work, we propose a novel approach that combines data augmentation via question-answer generation with…

Computation and Language · Computer Science 2024-09-16 Maximilian Kimmich , Andrea Bartezzaghi , Jasmina Bogojeska , Cristiano Malossi , Ngoc Thang Vu

We consider an aggregated human-AI collaboration aimed at generating a joint interpretable model. The model takes the form of Boolean decision rules, where human input is provided in the form of logical conditions or as partial templates.…

Human-Computer Interaction · Computer Science 2023-06-26 Rahul Nair

While AI shows promise for enhancing the efficiency of qualitative analysis, the unique human-AI interaction resulting from varied coding strategies makes it challenging to develop a trustworthy AI-assisted qualitative coding system (AIQCs)…

Human-Computer Interaction · Computer Science 2023-09-26 Jie Gao , Junming Cao , ShunYi Yeo , Kenny Tsu Wei Choo , Zheng Zhang , Toby Jia-Jun Li , Shengdong Zhao , Simon Tangi Perrault