Related papers: In-silico biological discovery with large perturba…

We discuss a method that employs a multilayer perceptron to detect deviations from a reference model in large multivariate datasets. Our data analysis strategy does not rely on any prior assumption on the nature of the deviation. It is…

Large Language Models (LLMs), particularly smaller variants, still struggle with complex reasoning tasks. While inference-time prompting can guide reasoning, existing methods often rely on sequential queries. Ensemble approaches offer a…

The recommendation of medication is a vital aspect of intelligent healthcare systems, as it involves prescribing the most suitable drugs based on a patient's specific health needs. Unfortunately, many sophisticated models currently in use…

Large language models (LLMs) are frequently fine-tuned or unlearned to adapt to new tasks or eliminate undesirable behaviors. While existing evaluation methods assess performance after such interventions, there remains no general approach…

Large language models (LLMs) are rapidly transforming materials science. This review examines recent LLM applications across the materials discovery pipeline, focusing on three key areas: mining scientific literature , predictive modelling,…

With the advent of Large Language Models (LLMs), generating rule-based data for real-world applications has become more accessible. Due to the inherent ambiguity of natural language and the complexity of rule sets, especially in long…

Large language models (LLMs) show potential as simulators of human behavior, offering a scalable way to study responses to interventions. However, because LLMs are trained largely on observational data, interventions in experiments with…

Embeddings have become a pivotal means to represent complex, multi-faceted information about entities, concepts, and relationships in a condensed and useful format. Nevertheless, they often preclude direct interpretation. While downstream…

Rapid advancements in imaging techniques and analytical methods over the past decade have revolutionized our ability to comprehensively probe the biological world at multiple scales, pinpointing the type, quantity, location, and even…

Probabilistic graphical models (PGMs) are widely used to discover latent structure in data, but their success hinges on selecting an appropriate model design. In practice, model specification is difficult and often requires iterative…

Beam prediction is an effective approach to reduce training overhead in massive multiple-input multiple-output (MIMO) systems. However, existing beam prediction models still exhibit limited generalization ability in diverse scenarios, which…

The utility of Large Language Models (LLMs) in analytical tasks is rooted in their vast pre-trained knowledge, which allows them to interpret ambiguous inputs and infer missing information. However, this same capability introduces a…

Large Language Models (LLMs) have demonstrated strong performance in handling complex tasks requiring both extensive knowledge and reasoning abilities. However, the existing LLM inference pipeline operates as an opaque process without…

Although behavioral studies have documented numerical reasoning errors in large language models (LLMs), the underlying representational mechanisms remain unclear. We hypothesize that numerical attributes occupy shared latent subspaces and…

Scientific discoveries often hinge on synthesizing decades of research, a task that potentially outstrips human information processing capacities. Large language models (LLMs) offer a solution. LLMs trained on the vast scientific literature…

Generative Large Language Models (LLMs) are capable of being in-context learners. However, the underlying mechanism of in-context learning (ICL) is still a major research question, and experimental research results about how models exploit…

Integrating external knowledge into large language models (LLMs) presents a promising solution to overcome the limitations imposed by their antiquated and static parametric memory. Prior studies, however, have tended to over-reliance on…

Extracting structured information from unstructured text is crucial for modeling real-world processes, but traditional schema mining relies on semi-structured data, limiting scalability. This paper introduces schema-miner, a novel tool that…

A fundamental aspect of biological information processing is the ubiquity of sequence-function relationships -- functions that map the sequence of DNA, RNA, or protein to a biochemically relevant activity. Most sequence-function…

Large language models (LLMs) have shown potential in assisting scientific research, yet their ability to discover high-quality research hypotheses remains unexamined due to the lack of a dedicated benchmark. To address this gap, we…