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The ability to continuously learn remains elusive for deep learning models. Unlike humans, models cannot accumulate knowledge in their weights when learning new tasks, mainly due to an excess of plasticity and the low incentive to reuse…

Machine Learning · Computer Science 2022-04-21 Vladimir Araujo , Julio Hurtado , Alvaro Soto , Marie-Francine Moens

Equivariant neural networks have proven to be effective for tasks with known underlying symmetries. However, optimizing equivariant networks can be tricky and best training practices are less established than for standard networks. In…

Machine Learning · Computer Science 2025-11-04 YuQing Xie , Tess Smidt

Supervised learning has proved effective for medical image analysis. However, it can utilize only the small labeled portion of data; it fails to leverage the large amounts of unlabeled data that is often available in medical image datasets.…

Computer Vision and Pattern Recognition · Computer Science 2020-04-28 Gaurav Fotedar , Nima Tajbakhsh , Shilpa Ananth , Xiaowei Ding

Backpropagation (BP) has been pivotal in advancing machine learning and remains essential in computational applications and comparative studies of biological and artificial neural networks. Despite its widespread use, the implementation of…

Neurons and Cognition · Quantitative Biology 2025-04-15 Xinhao Fan , Shreesh P Mysore

This paper introduces Uncertainty Propagation Network (UPN), a novel family of neural differential equations that naturally incorporate uncertainty quantification into continuous-time modeling. Unlike existing neural ODEs that predict only…

Machine Learning · Computer Science 2026-02-25 Hadi Jahanshahi , Zheng H. Zhu

This paper presents a feasibility study demonstrating that quantum machine learning (QML) algorithms achieve competitive performance on real-world medical imaging despite operating under severe constraints. We evaluate Equilibrium…

Emerging Technologies · Computer Science 2026-01-27 A. Bano , L. Liebovitch

Backpropagation is the cornerstone of deep learning, but its reliance on symmetric weight transport and global synchronization makes it computationally expensive and biologically implausible. Feedback alignment offers a promising…

Machine Learning · Computer Science 2025-05-28 Jeonghwan Cheon , Jaehyuk Bae , Se-Bum Paik

Machine learning techniques have received growing attention as an alternative strategy for developing general-purpose density functional approximations, augmenting the historically successful approach of human designed functionals derived…

Chemical Physics · Physics 2022-11-23 Kanun Pokharel , James W. Furness , Yi Yao , Volker Blum , Tom J. P. Irons , Andrew M. Teale , Jianwei Sun

This paper introduces a rate-based nonlinear neural network in which excitatory (E) neurons receive feedforward excitation from sensory (S) neurons, and inhibit each other through disynaptic pathways mediated by inhibitory (I) interneurons.…

Neurons and Cognition · Quantitative Biology 2019-01-01 H. Sebastian Seung

Predictive coding (PC) is a biologically plausible alternative to standard backpropagation (BP) that minimises an energy function with respect to network activities before updating weights. Recent work has improved the training stability of…

Machine Learning · Computer Science 2026-05-25 Francesco Innocenti , El Mehdi Achour , Rafal Bogacz

Due to the need to store the intermediate activations for back-propagation, end-to-end (E2E) training of deep networks usually suffers from high GPUs memory footprint. This paper aims to address this problem by revisiting the locally…

Computer Vision and Pattern Recognition · Computer Science 2021-01-27 Yulin Wang , Zanlin Ni , Shiji Song , Le Yang , Gao Huang

In the previous article, we introduced a neural network framework based on symmetric differential equations. This novel framework exhibits complete symmetry, endowing it with perfect mathematical properties. While we have examined some of…

Machine Learning · Computer Science 2024-11-25 Jiang Kun

Predictive coding (PC) is an influential theory in computational neuroscience, which argues that the cortex forms unsupervised world models by implementing a hierarchical process of prediction error minimization. PC networks (PCNs) are…

Neural and Evolutionary Computing · Computer Science 2022-08-05 Beren Millidge , Yuhang Song , Tommaso Salvatori , Thomas Lukasiewicz , Rafal Bogacz

Electrical Impedance Tomography (EIT) is a promising noninvasive imaging technique that reconstructs the spatial conductivity distribution from boundary voltage measurements. However, it poses a highly nonlinear and ill-posed inverse…

Signal Processing · Electrical Eng. & Systems 2025-12-16 Xuanxuan Yang , Yangming Zhang , Haofeng Chen , Gang Ma , Xiaojie Wang

We present a deep learning framework for quantifying and propagating uncertainty in systems governed by non-linear differential equations using physics-informed neural networks. Specifically, we employ latent variable models to construct…

Machine Learning · Statistics 2019-06-26 Yibo Yang , Paris Perdikaris

Large language models (LLMs) are trained on massive datasets that may include private or copyrighted content. Due to growing privacy and ownership concerns, data owners may request the removal of their data from trained models. Machine…

Machine Learning · Computer Science 2026-01-13 Zhihao Liu , Jian Lou , Yuke Hu , Xiaochen Li , Yitian Chen , Tailun Chen , Zhizhen Qin , Kui Ren , Zhan Qin

Backpropagation is widely used to train artificial neural networks, but its relationship to synaptic plasticity in the brain is unknown. Some biological models of backpropagation rely on feedback projections that are symmetric with…

Neurons and Cognition · Quantitative Biology 2023-02-08 Navid Shervani-Tabar , Robert Rosenbaum

Training neural networks is a challenging non-convex optimization problem, and backpropagation or gradient descent can get stuck in spurious local optima. We propose a novel algorithm based on tensor decomposition for guaranteed training of…

Machine Learning · Computer Science 2016-01-13 Majid Janzamin , Hanie Sedghi , Anima Anandkumar

The fields of artificial intelligence and neuroscience have a long history of fertile bi-directional interactions. On the one hand, important inspiration for the development of artificial intelligence systems has come from the study of…

Neurons and Cognition · Quantitative Biology 2019-11-21 Eilif B. Muller , Philippe Beaudoin

Modern distributed training relies heavily on communication compression to reduce the communication overhead. In this work, we study algorithms employing a popular class of contractive compressors in order to reduce communication overhead.…

Optimization and Control · Mathematics 2023-11-13 Yuan Gao , Rustem Islamov , Sebastian Stich
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