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Large language models (LLMs) are becoming increasingly relevant as a potential tool for healthcare, aiding communication between clinicians, researchers, and patients. However, traditional evaluations of LLMs on medical exam questions do…

Computation and Language · Computer Science 2023-09-19 Rojin Ziaei , Samuel Schmidgall

Large Language Models (LLMs) often produce explanations that do not faithfully reflect the factors driving their predictions. In healthcare settings, such unfaithfulness is especially problematic: explanations that omit salient clinical…

Computation and Language · Computer Science 2025-11-04 Teague McMillan , Gabriele Dominici , Martin Gjoreski , Marc Langheinrich

Large language models are increasingly relied upon as sources of information, but their propensity for generating false or misleading statements with high confidence poses risks for users and society. In this paper, we confront the critical…

Instruction-tuning enhances the ability of large language models (LLMs) to follow user instructions more accurately, improving usability while reducing harmful outputs. However, this process may increase the model's dependence on user…

Computation and Language · Computer Science 2025-07-25 Kyubeen Han , Junseo Jang , Hongjin Kim , Geunyeong Jeong , Harksoo Kim

Large language models (LLMs) have broad medical knowledge and can reason about medical information across many domains, holding promising potential for diverse medical applications in the near future. In this study, we demonstrate a…

Large Language Models (LLMs) are able to provide assistance on a wide range of information-seeking tasks. However, model outputs may be misleading, whether unintentionally or in cases of intentional deception. We investigate the ability of…

Computation and Language · Computer Science 2024-07-17 Betty Li Hou , Kejian Shi , Jason Phang , James Aung , Steven Adler , Rosie Campbell

Large language models (LLMs) have the potential to transform medicine, but real-world clinical scenarios contain extraneous information that can hinder performance. The rise of assistive technologies like ambient dictation, which…

Computation and Language · Computer Science 2025-04-03 Krithik Vishwanath , Anton Alyakin , Daniel Alexander Alber , Jin Vivian Lee , Douglas Kondziolka , Eric Karl Oermann

As large language models (LLMs) rapidly displace traditional expertise, their capacity to correct misinformation has become a core concern. We investigate the idea that prompt framing systematically modulates misinformation correction -…

Human-Computer Interaction · Computer Science 2025-12-01 Sekoul Krastev , Hilary Sweatman , Anni Sternisko , Steve Rathje

Rapid integration of large language models (LLMs) in health care is sparking global discussion about their potential to revolutionize health care quality and accessibility. At a time when improving health care quality and access remains a…

Computers and Society · Computer Science 2025-04-01 Troy Zada , Natalie Tam , Francois Barnard , Marlize Van Sittert , Venkat Bhat , Sirisha Rambhatla

Large Language Models (LLMs) have demonstrated impressive capabilities in reasoning, positioning them as promising tools for supporting human problem-solving. However, what happens when their performance is affected by misinformation, i.e.,…

Computation and Language · Computer Science 2025-09-24 Yiyang Feng , Yichen Wang , Shaobo Cui , Boi Faltings , Mina Lee , Jiawei Zhou

Large Language Models (LLMs) increasingly show reasoning rationales alongside their answers, turning "reasoning" into a user-interface element. While step-by-step rationales are typically associated with model performance, how they…

Human-Computer Interaction · Computer Science 2026-03-10 Xin Sun , Shu Wei , Jos A Bosch , Isao Echizen , Saku Sugawara , Abdallah El Ali

Large Language Models (LLMs) are increasingly applied to medical imaging tasks, including image interpretation and synthetic image generation. However, these models often produce hallucinations, which are confident but incorrect outputs…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Anindya Bijoy Das , Shahnewaz Karim Sakib , Shibbir Ahmed

Large language models (LLMs) make it possible to generate synthetic behavioural data at scale, offering an ethical and low-cost alternative to human experiments. Whether such data can faithfully capture psychological differences driven by…

Computation and Language · Computer Science 2025-11-27 Manuel Pratelli , Marinella Petrocchi

Large language models (LLMs) have demonstrated impressive performance across various domains. However, for clinical diagnosis, higher expectations are required for LLM's reliability and sensitivity: thinking like physicians and remaining…

Computation and Language · Computer Science 2025-04-21 Chenwei Yan , Xiangling Fu , Yuxuan Xiong , Tianyi Wang , Siu Cheung Hui , Ji Wu , Xien Liu

Large language models (LLMs) can produce erroneous responses that sound fluent and convincing, raising the risk that users will rely on these responses as if they were correct. Mitigating such overreliance is a key challenge. Through a…

Human-Computer Interaction · Computer Science 2025-02-13 Sunnie S. Y. Kim , Jennifer Wortman Vaughan , Q. Vera Liao , Tania Lombrozo , Olga Russakovsky

While Large Language Models (LLMs) can amplify online misinformation, they also show promise in tackling misinformation. In this paper, we empirically study the capabilities of three LLMs -- ChatGPT, Gemini, and Claude -- in countering…

Computation and Language · Computer Science 2025-09-29 Adiba Mahbub Proma , Neeley Pate , James Druckman , Gourab Ghoshal , Hangfeng He , Ehsan Hoque

Large Language Models (LLMs) have made significant advances in natural language processing, but their underlying mechanisms are often misunderstood. Despite exhibiting coherent answers and apparent reasoning behaviors, LLMs rely on…

Computation and Language · Computer Science 2024-08-05 Bo Zhou , Daniel Geißler , Paul Lukowicz

While state-of-the-art large language models (LLMs) have shown impressive performance on many tasks, there has been extensive research on undesirable model behavior such as hallucinations and bias. In this work, we investigate how the…

Computation and Language · Computer Science 2025-11-07 Elinor Poole-Dayan , Deb Roy , Jad Kabbara

Medical large language model (LLM) evaluations rely on simplified, exam-style benchmarks that rarely reflect the ambiguity of real-world medical inquiries. We introduce the CLinical Evaluation of Ambiguity and Reliability (CLEAR) framework,…

Computation and Language · Computer Science 2026-05-12 Kevin H. Guo , Chao Yan , Avinash Baidya , Katherine Brown , Xiang Gao , Juming Xiong , Zhijun Yin , Bradley A. Malin

Large language models (LLMs) have achieved a degree of success in generating coherent and contextually relevant text, yet they remain prone to a significant challenge known as hallucination: producing information that is not substantiated…

Computation and Language · Computer Science 2024-10-28 Ray Li , Tanishka Bagade , Kevin Martinez , Flora Yasmin , Grant Ayala , Michael Lam , Kevin Zhu
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