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Despite recent improvements in the accuracy of brain tumor segmentation, the results still exhibit low levels of confidence and robustness. Uncertainty estimation is one effective way to change this situation, as it provides a measure of…

Image and Video Processing · Electrical Eng. & Systems 2022-07-29 Ke Zou , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Virtual Diagnostic (VD) is a computational tool based on deep learning that can be used to predict a diagnostic output. VDs are especially useful in systems where measuring the output is invasive, limited, costly or runs the risk of…

Accelerator Physics · Physics 2021-08-04 Owen Convery , Lewis Smith , Yarin Gal , Adi Hanuka

Uncertainty estimation, which provides a means of building explainable neural networks for medical imaging applications, have mostly been studied for single deep learning models that focus on a specific task. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Leonhard F. Feiner , Martin J. Menten , Kerstin Hammernik , Paul Hager , Wenqi Huang , Daniel Rueckert , Rickmer F. Braren , Georgios Kaissis

In this work, we present a novel application of an uncertainty-quantification framework called Deep Evidential Learning in the domain of radiotherapy dose prediction. Using medical images of the Open Knowledge-Based Planning Challenge…

Machine Learning · Computer Science 2024-09-24 Hai Siong Tan , Kuancheng Wang , Rafe Mcbeth

Deep learning has shown promising contributions in medical image segmentation with powerful learning and feature representation abilities. However, it has limitations for reasoning with and combining imperfect (imprecise, uncertain, and…

Computer Vision and Pattern Recognition · Computer Science 2023-09-13 Ling Huang

We introduce Bayesian QuickNAT for the automated quality control of whole-brain segmentation on MRI T1 scans. Next to the Bayesian fully convolutional neural network, we also present inherent measures of segmentation uncertainty that allow…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Abhijit Guha Roy , Sailesh Conjeti , Nassir Navab , Christian Wachinger

Deep neural networks excel in perception tasks such as semantic segmentation and monocular depth estimation, making them indispensable in safety-critical applications like autonomous driving and industrial inspection. However, they often…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Steven Landgraf , Markus Hillemann , Theodor Kapler , Markus Ulrich

Image segmentation relies heavily on neural networks which are known to be overconfident, especially when making predictions on out-of-distribution (OOD) images. This is a common scenario in the medical domain due to variations in…

Computer Vision and Pattern Recognition · Computer Science 2024-07-24 Kilian Zepf , Selma Wanna , Marco Miani , Juston Moore , Jes Frellsen , Søren Hauberg , Frederik Warburg , Aasa Feragen

Reliable uncertainty estimation has become a crucial requirement for the industrial deployment of deep learning algorithms, particularly in high-risk applications such as autonomous driving and medical diagnosis. However, mainstream…

Machine Learning · Computer Science 2024-09-10 Junyu Gao , Mengyuan Chen , Liangyu Xiang , Changsheng Xu

Bayesian neural networks and deep ensemble methods have been proposed for uncertainty quantification; however, they are computationally intensive and require large storage. By utilizing a single deterministic model, we can solve the above…

Machine Learning · Computer Science 2025-08-04 Yaxin Ma , Benjamin Colburn , Jose C. Principe

Uncertainty quantification by ensemble learning is explored in terms of an application from computational optical form measurements. The application requires to solve a large-scale, nonlinear inverse problem. Ensemble learning is used to…

Machine Learning · Computer Science 2021-03-03 Lara Hoffmann , Ines Fortmeier , Clemens Elster

Deep learning (DL) models for segmenting various anatomical structures have achieved great success via a static DL model that is trained in a single source domain. Yet, the static DL model is likely to perform poorly in a continually…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Xiaofeng Liu , Helen A. Shih , Fangxu Xing , Emiliano Santarnecchi , Georges El Fakhri , Jonghye Woo

Deep hedging trains neural networks to manage derivative risk under market frictions, but produces hedge ratios with no measure of model confidence -- a significant barrier to deployment. We introduce uncertainty quantification to the deep…

Computational Finance · Quantitative Finance 2026-03-12 Manan Poddar

Emerging deep-learning (DL)-based techniques have significant potential to revolutionize biomedical imaging. However, one outstanding challenge is the lack of reliability assessment in the DL predictions, whose errors are commonly revealed…

Image and Video Processing · Electrical Eng. & Systems 2019-05-07 Yujia Xue , Shiyi Cheng , Yunzhe Li , Lei Tian

Active learning is a unique abstraction of machine learning techniques where the model/algorithm could guide users for annotation of a set of data points that would be beneficial to the model, unlike passive machine learning. The primary…

Computer Vision and Pattern Recognition · Computer Science 2021-01-08 Vishwesh Nath , Dong Yang , Bennett A. Landman , Daguang Xu , Holger R. Roth

Convolutional Neural Networks (CNNs) have shown to be powerful medical image segmentation models. In this study, we address some of the main unresolved issues regarding these models. Specifically, training of these models on small medical…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Davood Karimi , Ali Gholipour

Although neural networks have seen tremendous success as predictive models in a variety of domains, they can be overly confident in their predictions on out-of-distribution (OOD) data. To be viable for safety-critical applications, like…

Robotics · Computer Science 2022-11-17 Masha Itkina , Mykel J. Kochenderfer

We provide single-model estimates of aleatoric and epistemic uncertainty for deep neural networks. To estimate aleatoric uncertainty, we propose Simultaneous Quantile Regression (SQR), a loss function to learn all the conditional quantiles…

Machine Learning · Statistics 2019-09-09 Natasa Tagasovska , David Lopez-Paz

Deep neural networks have achieved significant success in the last decades, but they are not well-calibrated and often produce unreliable predictions. A large number of literature relies on uncertainty quantification to evaluate the…

Machine Learning · Computer Science 2023-11-13 Russell Alan Hart , Linlin Yu , Yifei Lou , Feng Chen

In addition to accurate scene understanding through precise semantic segmentation of LiDAR point clouds, detecting out-of-distribution (OOD) objects, instances not encountered during training, is essential to prevent the incorrect…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Hanieh Shojaei Miandashti , Claus Brenner