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In contemporary society, the issue of psychological health has become increasingly prominent, characterized by the diversification, complexity, and universality of mental disorders. Cognitive Behavioral Therapy (CBT), currently the most…

Computation and Language · Computer Science 2024-07-26 Hao Shen , Zihan Li , Minqiang Yang , Minghui Ni , Yongfeng Tao , Zhengyang Yu , Weihao Zheng , Chen Xu , Bin Hu

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Large language models (LLMs) hold significant potential for mental health support, capable of generating empathetic responses and simulating therapeutic conversations. However, existing LLM-based approaches often lack the clinical grounding…

Computation and Language · Computer Science 2025-11-04 He Hu , Yucheng Zhou , Juzheng Si , Qianning Wang , Hengheng Zhang , Fuji Ren , Fei Ma , Laizhong Cui , Qi Tian

Clinical decision-making requires reasoning over incomplete, imprecise, and linguistically expressed patient narratives. While large language models (LLMs) excel at extracting latent information from natural language, they lack the…

Artificial Intelligence · Computer Science 2026-05-26 Xiaoyang Fan , Yufan Cai , Zhe Hou , Jin Song Dong

The widespread adoption of large language models (LLMs) in healthcare raises critical questions about their ability to interpret patient-generated narratives, which are often informal, ambiguous, and noisy. Existing benchmarks typically…

Computation and Language · Computer Science 2025-09-16 Eden Mama , Liel Sheri , Yehudit Aperstein , Alexander Apartsin

With the wide adoption of large language models (LLMs) in information assistance, it is essential to examine their alignment with human communication styles and values. We situate this study within the context of fact-checking health…

Human-Computer Interaction · Computer Science 2025-05-14 Jiawei Zhou , Kritika Venkatachalam , Minje Choi , Koustuv Saha , Munmun De Choudhury

The advent of large language models (LLMs) has significantly advanced various fields, including natural language processing and automated dialogue systems. This paper explores the application of LLMs in psychological counseling, addressing…

Computation and Language · Computer Science 2024-06-21 Wenjie Li , Tianyu Sun , Kun Qian , Wenhong Wang

Objectives: While Large Language Models (LLMs) have been widely used to assist clinicians and support patients, no existing work has explored dialogue systems for standard diagnostic interviews and assessments. This study aims to bridge the…

Computation and Language · Computer Science 2025-05-01 Sichang Tu , Abigail Powers , Stephen Doogan , Jinho D. Choi

This research tests the role of Large Language Models (LLMs) as formal second opinion tools in professional decision-making, particularly focusing on complex medical cases where even experienced physicians seek peer consultation. The work…

Cryptography and Security · Computer Science 2024-10-29 David Noever

Lab results are often confusing and hard to understand. Large language models (LLMs) such as ChatGPT have opened a promising avenue for patients to get their questions answered. We aim to assess the feasibility of using LLMs to generate…

Computation and Language · Computer Science 2024-04-23 Zhe He , Balu Bhasuran , Qiao Jin , Shubo Tian , Karim Hanna , Cindy Shavor , Lisbeth Garcia Arguello , Patrick Murray , Zhiyong Lu

The rapid advancements in large language models (LLMs) have opened up new opportunities for transforming patient engagement in healthcare through conversational AI. This paper presents an overview of the current landscape of LLMs in…

Artificial Intelligence · Computer Science 2024-11-27 Bo Wen , Raquel Norel , Julia Liu , Thaddeus Stappenbeck , Farhana Zulkernine , Huamin Chen

Large language models (LLMs) have shown impressive capabilities in natural language processing tasks, including dialogue generation. This research aims to conduct a novel comparative analysis of two prominent techniques, fine-tuning with…

Family caregivers often face substantial mental health challenges due to their multifaceted roles and limited resources. This study explored the potential of a large language model (LLM)-powered conversational agent to deliver…

Physicians considering clinical trials for their patients are met with the laborious process of checking many text based eligibility criteria. Large Language Models (LLMs) have shown to perform well for clinical information extraction and…

Machine Learning · Computer Science 2023-06-30 Danny M. den Hamer , Perry Schoor , Tobias B. Polak , Daniel Kapitan

Large language models (LLMs) excel on many NLP benchmarks, but their behavior on real-world, semi-structured prediction remains underexplored. We present LlaMADRS, a benchmark for structured clinical assessment from dialogue built on the…

Human-Computer Interaction · Computer Science 2026-04-23 Gaoussou Youssouf Kebe , Jeffrey M. Girard , Einat Liebenthal , Justin Baker , Fernando De la Torre , Louis-Philippe Morency

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

Large Language Models (LLMs),such as ChatGPT, are increasingly used in research, ranging from simple writing assistance to complex data annotation tasks. Recently, some research has suggested that LLMs may even be able to simulate human…

Artificial Intelligence · Computer Science 2025-08-14 Sarah Schröder , Thekla Morgenroth , Ulrike Kuhl , Valerie Vaquet , Benjamin Paaßen

Empathy is central to human connection, yet people often struggle to express it effectively. In blinded evaluations, large language models (LLMs) generate responses that are often judged more empathic than human-written ones. Yet when a…

Computation and Language · Computer Science 2026-03-17 Aakriti Kumar , Nalin Poungpeth , Diyi Yang , Bruce Lambert , Matthew Groh

Mental illness remains one of the most critical public health issues. Despite its importance, many mental health professionals highlight a disconnect between their training and actual real-world patient practice. To help bridge this gap, we…

A long-standing challenge in developing accurate recommendation models is simulating user behavior, mainly due to the complex and stochastic nature of user interactions. Towards this, one promising line of work has been the use of Large…

Information Retrieval · Computer Science 2025-09-15 Himanshu Thakur , Eshani Agrawal , Smruthi Mukund
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