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Live-cell imaging of multiple subcellular structures is essential for understanding subcellular dynamics. However, the conventional multi-color sequential fluorescence microscopy suffers from significant imaging delays and limited number of…

Subcellular Processes · Quantitative Biology 2025-01-13 Mingyang Chen , Luhong Jin , Xuwei Xuan , Defu Yang , Yun Cheng , Ju Zhang

Deep learning based methods hold state-of-the-art results in image denoising, but remain difficult to interpret due to their construction from poorly understood building blocks such as batch-normalization, residual learning, and feature…

Image and Video Processing · Electrical Eng. & Systems 2021-03-09 Nikola Janjušević , Amirhossein Khalilian-Gourtani , Yao Wang

We present a novel approach for extracting 3D atomic-level information from transmission electron microscopy (TEM) images affected by significant noise. The approach is based on formulating depth estimation as a semantic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Matan Leibovich , Mai Tan , Ramon Manzorro , Adria Marcos-Morales , Sreyas Mohan , Peter A. Crozier , Carlos Fernandez-Granda

Seismic acoustic impedance inversion is one of the most challenging tasks in geophysical exploration. Many studies have proposed the use of deep learning for processing; however, most of them are limited by factors such as seismic wavelets…

Geophysics · Physics 2025-12-15 Junheng Peng , Xiaowen Wang , Yingtian Liu , Yong Li , Mingwei Wang

Image denoising is a typical ill-posed problem due to complex degradation. Leading methods based on normalizing flows have tried to solve this problem with an invertible transformation instead of a deterministic mapping. However, the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Wenchao Du , Hu Chen , Yi Zhang , H. Yang

Inversion of electromagnetic data finds applications in many areas of geophysics. The inverse problem is commonly solved with either deterministic optimization methods (such as the nonlinear conjugate gradient or Gauss-Newton) which are…

Geophysics · Physics 2019-12-03 Vladimir Puzyrev , Andrei Swidinsky

Airborne transient electromagnetic (TEM) is a cost-effective method to image the distribution of electrical conductivity in the ground. We consider layered earth inversion to interpret large data sets of hundreds of kilometre. Different…

Geophysics · Physics 2012-07-17 Julien Guillemoteau , Pascal Sailhac , Mickael Behaegel

SUMMARY Geophysical imaging using the inversion procedure is a powerful tool for the exploration of the Earth's subsurface. However, the interpretation of inverted images can sometimes be difficult, due to the inherent limitations of…

Deep learning-based image denoising techniques often struggle with poor generalization performance to out-of-distribution real-world noise. To tackle this challenge, we propose a novel noise translation framework that performs denoising on…

Image and Video Processing · Electrical Eng. & Systems 2026-04-03 Inju Ha , Donghun Ryou , Seonguk Seo , Bohyung Han

The possibility to have results very quickly after, or even during, the collection of electromagnetic data would be important, not only for quality check purposes, but also for adjusting the location of the proposed flight lines during an…

Geophysics · Physics 2020-11-09 Peng Bai , Giulio Vignoli , Andrea Viezzoli , Jouni Nevalainen , Giuseppina Vacca

Inference and prediction under partial knowledge of a physical system is challenging, particularly when multiple confounding sources influence the measured response. Explicitly accounting for these influences in physics-based models is…

Machine Learning · Statistics 2026-01-14 Ioannis Christoforos Koune , Alice Cicirello

This study focuses on inverting time-domain airborne electromagnetic data in 2D by training a neural-network to understand the relationship between data and conductivity, thereby removing the need for expensive forward modeling during the…

Electrical Impedance Tomography (EIT) is a promising noninvasive imaging technique that reconstructs the spatial conductivity distribution from boundary voltage measurements. However, it poses a highly nonlinear and ill-posed inverse…

Signal Processing · Electrical Eng. & Systems 2025-12-16 Xuanxuan Yang , Yangming Zhang , Haofeng Chen , Gang Ma , Xiaojie Wang

Machine learning methods, such as deep learning, show promising results in the medical domain. However, the lack of interpretability of these algorithms may hinder their applicability to medical decision support systems. This paper studies…

Signal Processing · Electrical Eng. & Systems 2021-07-23 Juan Manuel Mayor-Torres , Mirco Ravanelli , Sara E. Medina-DeVilliers , Matthew D. Lerner , Giuseppe Riccardi

Recently, many forms of audio industrial applications, such as sound monitoring and source localization, have begun exploiting smart multi-modal devices equipped with a microphone array. Regrettably, model-based methods are often difficult…

Sound · Computer Science 2023-06-21 Hao Liang , Guanxing Zhou , Xiaotong Tu , Andreas Jakobsson , Xinghao Ding , Yue Huang

Compared with traditional seismic noise attenuation algorithms that depend on signal models and their corresponding prior assumptions, removing noise with a deep neural network is trained based on a large training set, where the inputs are…

Geophysics · Physics 2019-07-23 Siwei Yu , Jianwei Ma , Wenlong Wang

With the mass construction of Gen III nuclear reactors, it is a popular trend to use deep learning (DL) techniques for fast and effective diagnosis of possible accidents. To overcome the common problems of previous work in diagnosing…

Signal Processing · Electrical Eng. & Systems 2022-09-26 Chengyuan Li , Zhifang Qiu , Zhangrui Yan , Meifu Li

In recent years, deep learning has shown potential and efficiency in a wide area including computer vision, image and signal processing. Yet, translational challenges remain for user applications due to a lack of interpretability of…

Machine Learning · Computer Science 2022-07-12 Hamid Niknazar , Sara C. Mednick

Recent advances in scanning transmission electron and scanning probe microscopies have opened exciting opportunities in probing the materials structural parameters and various functional properties in real space with angstrom-level…

In human perception and cognition, a fundamental operation that brains perform is interpretation: constructing coherent neural states from noisy, incomplete, and intrinsically ambiguous evidence. The problem of interpretation is well…

Machine Learning · Computer Science 2019-09-30 Michael Iuzzolino , Yoram Singer , Michael C. Mozer