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In the effort to aid cytologic diagnostics by establishing automatic single cell screening using high throughput digital holographic microscopy for clinical studies thousands of images and millions of cells are captured. The bottleneck lies…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Julia Sistermanns , Ellen Emken , Gregor Weirich , Oliver Hayden , Wolfgang Utschick

We present a deep learning segmentation model that can automatically and robustly segment all major anatomical structures in body CT images. In this retrospective study, 1204 CT examinations (from the years 2012, 2016, and 2020) were used…

This paper proposes LiNUS, a lightweight deep learning framework for the automatic segmentation of the Subthalamic Nucleus (STN) in Deep Brain Stimulation (DBS) surgery. Addressing the challenges of small target volume and class imbalance…

Image and Video Processing · Electrical Eng. & Systems 2026-01-22 Shuo Zhang , Zihua Wang , Changgeng He , Chunhua Hu

Automated segmentation of medical imaging is of broad interest to clinicians and machine learning researchers alike. The goal of segmentation is to increase efficiency and simplicity of visualization and quantification of regions of…

Image and Video Processing · Electrical Eng. & Systems 2020-06-04 Shruti Jadon , Owen P. Leary , Ian Pan , Tyler J. Harder , David W. Wright , Lisa H. Merck , Derek L. Merck

Segmenting histology images into diagnostically relevant regions is imperative to support timely and reliable decisions by pathologists. To this end, computer-aided techniques have been proposed to delineate relevant regions in scanned…

Gigapixel medical images provide massive data, both morphological textures and spatial information, to be mined. Due to the large data scale in histology, deep learning methods play an increasingly significant role as feature extractors.…

Image and Video Processing · Electrical Eng. & Systems 2022-06-16 Yiqing Shen , Bingxin Zhou , Xinye Xiong , Ruitian Gao , Yu Guang Wang

Image segmentation aims to partition an image according to the objects in the scene and is a fundamental step in analysing very high spatial-resolution (VHR) remote sensing imagery. Current methods struggle to effectively consider land…

Computer Vision and Pattern Recognition · Computer Science 2024-01-08 Xianwei Lv , Claudio Persello , Wangbin Li , Xiao Huang , Dongping Ming , Alfred Stein

Medical image segmentation is of great significance in analysis of illness. The use of deep neural networks in medical image segmentation can help doctors extract regions of interest from complex medical images, thereby improving diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Zhuoyi Fang , Kexuan Shi , Jiajia Liu , Qiang Han

Tumor segmentation in whole-slide images of histology slides is an important step towards computer-assisted diagnosis. In this work, we propose a tumor segmentation framework based on the novel concept of persistent homology profiles…

Computer Vision and Pattern Recognition · Computer Science 2018-05-11 Talha Qaiser , Yee-Wah Tsang , Daiki Taniyama , Naoya Sakamoto , Kazuaki Nakane , David Epstein , Nasir Rajpoot

In this paper, we present a novel method for the segmentation of breast masses from mammograms exploring structured and deep learning. Specifically, using structured support vector machine (SSVM), we formulate a model that combines…

Computer Vision and Pattern Recognition · Computer Science 2014-12-08 Neeraj Dhungel , Gustavo Carneiro , Andrew P. Bradley

The claustrum is a thin gray matter structure in each brain hemisphere, characterized by exceptionally high connectivity with nearly all brain regions. Despite extensive animal studies on its anatomy and function and growing evidence of…

Neurons and Cognition · Quantitative Biology 2025-05-16 Steven Seung-Suk Kang , Joseph Bodenheimer , Kayley Morris , Tracey Butler

Accurate segmentation and classification of nuclei in histology images is critical but challenging due to nuclei heterogeneity, staining variations, and tissue complexity. Existing methods often struggle with limited dataset variability,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Wenhua Zhang , Sen Yang , Meiwei Luo , Chuan He , Yuchen Li , Jun Zhang , Xiyue Wang , Fang Wang

Digital pathology is one of the most significant developments in modern medicine. Pathological examinations are the gold standard of medical protocols and play a fundamental role in diagnosis. Recently, with the advent of digital scanners,…

Image and Video Processing · Electrical Eng. & Systems 2021-12-09 Mahdi Arab Loodaricheh , Nader Karimi , Shadrokh Samavi

Nuclei segmentation is a fundamental task in digital pathology analysis and can be automated by deep learning-based methods. However, the development of such an automated method requires a large amount of data with precisely annotated masks…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Jiangbo Shi , Chang Jia , Zeyu Gao , Tieliang Gong , Chunbao Wang , Chen Li

Magnetic resonance imaging (MRI) has been proposed as a complimentary method to measure bone quality and assess fracture risk. However, manual segmentation of MR images of bone is time-consuming, limiting the use of MRI measurements in the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-06 Cem M. Deniz , Siyuan Xiang , Spencer Hallyburton , Arakua Welbeck , James S. Babb , Stephen Honig , Kyunghyun Cho , Gregory Chang

Accurate automatic segmentation of brain anatomy from $T_1$-weighted~($T_1$-w) magnetic resonance images~(MRI) has been a computationally intensive bottleneck in neuroimaging pipelines, with state-of-the-art results obtained by unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Amod Jog , Bruce Fischl

We propose a segmentation framework that uses deep neural networks and introduce two innovations. First, we describe a biophysics-based domain adaptation method. Second, we propose an automatic method to segment white and gray matter, and…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Amir Gholami , Shashank Subramanian , Varun Shenoy , Naveen Himthani , Xiangyu Yue , Sicheng Zhao , Peter Jin , George Biros , Kurt Keutzer

The objective of this study was to develop a PET tumor-segmentation framework that addresses the challenges of limited spatial resolution, high image noise, and lack of clinical training data with ground-truth tumor boundaries in PET…

Glioblastomas are the most aggressive fast-growing primary brain cancer which originate in the glial cells of the brain. Accurate identification of the malignant brain tumor and its sub-regions is still one of the most challenging problems…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Ramy A. Zeineldin , Mohamed E. Karar , Franziska Mathis-Ullrich , Oliver Burgert

The accurate automatic segmentation of gliomas and its intra-tumoral structures is important not only for treatment planning but also for follow-up evaluations. Several methods based on 2D and 3D Deep Neural Networks (DNN) have been…

Image and Video Processing · Electrical Eng. & Systems 2020-01-28 Parth Natekar , Avinash Kori , Ganapathy Krishnamurthi
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