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Abnormal iron accumulation in the brain subcortical nuclei has been reported to be correlated to various neurodegenerative diseases, which can be measured through the magnetic susceptibility from the quantitative susceptibility mapping…

Image and Video Processing · Electrical Eng. & Systems 2020-08-04 Chao Chai , Pengchong Qiao , Bin Zhao , Huiying Wang , Guohua Liu , Hong Wu , E Mark Haacke , Wen Shen , Chen Cao , Xinchen Ye , Zhiyang Liu , Shuang Xia

Background: Cell segmentation in bright-field histological slides is a crucial topic in medical image analysis. Having access to accurate segmentation allows researchers to examine the relationship between cellular morphology and clinical…

In the last two decades, neuroscience has produced intriguing evidence for a central role of the claustrum in mammalian forebrain structure and function. However, relatively few in vivo studies of the claustrum exist in humans. A reason for…

Image and Video Processing · Electrical Eng. & Systems 2023-05-24 Hongwei Li , Aurore Menegaux , Benita Schmitz-Koep , Antonia Neubauer , Felix JB Bäuerlein , Suprosanna Shit , Christian Sorg , Bjoern Menze , Dennis Hedderich

Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…

Machine Learning · Statistics 2018-06-28 Jens Behrmann , Christian Etmann , Tobias Boskamp , Rita Casadonte , Jörg Kriegsmann , Peter Maass

Automatic segmentation is essential for the brain tumor diagnosis, disease prognosis, and follow-up therapy of patients with gliomas. Still, accurate detection of gliomas and their sub-regions in multimodal MRI is very challenging due to…

Image and Video Processing · Electrical Eng. & Systems 2022-12-20 Ramy A. Zeineldin , Mohamed E. Karar , Oliver Burgert , Franziska Mathis-Ullrich

It remains challenging to automatically segment kidneys in clinical ultrasound images due to the kidneys' varied shapes and image intensity distributions, although semi-automatic methods have achieved promising performance. In this study,…

Computer Vision and Pattern Recognition · Computer Science 2019-01-09 Shi Yin , Zhengqiang Zhang , Hongming Li , Qinmu Peng , Xinge You , Susan L. Furth , Gregory E. Tasian , Yong Fan

Purpose: To improve kidney segmentation in clinical ultrasound (US) images, we develop a new graph cuts based method to segment kidney US images by integrating original image intensity information and texture feature maps extracted using…

Computer Vision and Pattern Recognition · Computer Science 2017-06-13 Qiang Zheng , Steven Warner , Gregory Tasian , Yong Fan

Automated volumetric segmentation of the pancreas on cross-sectional imaging is needed for diagnosis and follow-up of pancreatic diseases. While CT-based pancreatic segmentation is more established, MRI-based segmentation methods are…

Detection of brain tumor using a segmentation based approach is critical in cases, where survival of a subject depends on an accurate and timely clinical diagnosis. Gliomas are the most commonly found tumors having irregular shape and…

Computer Vision and Pattern Recognition · Computer Science 2018-04-16 Saddam Hussain , Syed Muhammad Anwar , Muhammad Majid

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

A key limitation of deep convolutional neural networks (DCNN) based image segmentation methods is the lack of generalizability. Manually traced training images are typically required when segmenting organs in a new imaging modality or from…

Computer Vision and Pattern Recognition · Computer Science 2019-10-01 Yuankai Huo , Zhoubing Xu , Hyeonsoo Moon , Shunxing Bao , Albert Assad , Tamara K. Moyo , Michael R. Savona , Richard G. Abramson , Bennett A. Landman

Although deep neural networks have been a dominant method for many 2D vision tasks, it is still challenging to apply them to 3D tasks, such as medical image segmentation, due to the limited amount of annotated 3D data and limited…

Computer Vision and Pattern Recognition · Computer Science 2020-11-02 Yingwei Li , Zhuotun Zhu , Yuyin Zhou , Yingda Xia , Wei Shen , Elliot K. Fishman , Alan L. Yuille

Accurate and reliable brain tumor segmentation is a critical component in cancer diagnosis, treatment planning, and treatment outcome evaluation. Build upon successful deep learning techniques, a novel brain tumor segmentation method is…

Computer Vision and Pattern Recognition · Computer Science 2017-11-13 Xiaomei Zhao , Yihong Wu , Guidong Song , Zhenye Li , Yazhuo Zhang , Yong Fan

The recent surge in performance for image analysis of digitised pathology slides can largely be attributed to the advances in deep learning. Deep models can be used to initially localise various structures in the tissue and hence facilitate…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Simon Graham , Quoc Dang Vu , Mostafa Jahanifar , Shan E Ahmed Raza , Fayyaz Minhas , David Snead , Nasir Rajpoot

Gliomas are brain tumors composed of different highly heterogeneous histological subregions. Image analysis techniques to identify relevant tumor substructures have high potential for improving patient diagnosis, treatment and prognosis.…

Image and Video Processing · Electrical Eng. & Systems 2022-07-18 José Gerardo Suárez-García Javier Miguel Hernández-López , Eduardo Moreno-Barbosa , Benito de Celis-Alonso

Gliomas are aggressive brain tumors that require accurate imaging-based diagnosis, with segmentation playing a critical role in evaluating morphology and treatment decisions. Manual delineation of gliomas is time-consuming and prone to…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Cecilia Diana-Albelda , Roberto Alcover-Couso , Álvaro García-Martín , Jesus Bescos , Marcos Escudero-Viñolo

Purpose: Different Magnetic resonance imaging (MRI) modalities of the same anatomical structure are required to present different pathological information from the physical level for diagnostic needs. However, it is often difficult to…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Yuchen Fei , Bo Zhan , Mei Hong , Xi Wu , Jiliu Zhou , Yan Wang

Accurate segmentation of 3-D cell nuclei in microscopy images is essential for the study of nuclear organization, gene expression, and cell morphodynamics. Current image segmentation methods are challenged by the complexity and variability…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 Sundaresh Ram , Jeffrey J. Rodriguez

Lesion segmentation is an important problem in computer-assisted diagnosis that remains challenging due to the prevalence of low contrast, irregular boundaries that are unamenable to shape priors. We introduce Deep Active Lesion…

Image and Video Processing · Electrical Eng. & Systems 2020-09-01 Ali Hatamizadeh , Assaf Hoogi , Debleena Sengupta , Wuyue Lu , Brian Wilcox , Daniel Rubin , Demetri Terzopoulos