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Predicting the emergence of multiple chronic conditions (MCC) is crucial for early intervention and personalized healthcare, as MCC significantly impacts patient outcomes and healthcare costs. Graph neural networks (GNNs) are effective…

One of the most urgent problems is the overcrowding in emergency departments (EDs), caused by an aging population and rising healthcare costs. Patient dispositions have become more complex as a result of the strain on hospital…

Machine Learning · Computer Science 2024-12-23 Nafisa Binte Feroz , Chandrima Sarker , Tanzima Ahsan , K M Arefeen Sultan , Raqeebir Rab

L\'evy processes are widely used in financial mathematics, telecommunication, economics, queueing theory and natural sciences for modelling. We propose an essentially asymptotically efficient estimation method for the system parameters of…

Statistics Theory · Mathematics 2014-04-14 Máté Mánfay , László Gerencsér , Zsanett Orlovits

In the treatment of complex diseases, treatment regimens using a single drug often yield limited efficacy and can lead to drug resistance. In contrast, combination drug therapies can significantly improve therapeutic outcomes through…

Machine Learning · Computer Science 2026-04-24 Jiyan Song , Wenyang Wang , Chengcheng Yan , Zhiquan Han , Feifei Zhao

Recent advances in the masked autoencoder (MAE) paradigm have significantly propelled self-supervised skeleton-based action recognition. However, most existing approaches limit reconstruction targets to raw joint coordinates or their simple…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Shengkai Sun , Zefan Zhang , Jianfeng Dong , Zhiyong Cheng , Xiaojun Chang , Meng Wang

Every day, poison control centers (PCC) are called for immediate classification and treatment recommendations if an acute intoxication is suspected. Due to the time-sensitive nature of these cases, doctors are required to propose a correct…

The automatic classification of medical time series signals, such as electroencephalogram (EEG) and electrocardiogram (ECG), plays a pivotal role in clinical decision support and early detection of diseases. Although Transformer based…

Machine Learning · Computer Science 2025-09-22 Ming Hu , Jianfu Yin , Mingyu Dou , Yuqi Wang , Ruochen Dang , Siyi Liang , Feiyu Zhu , Cong Hu , Yao Wang , Bingliang Hu , Quan Wang

Understanding disease similarity is critical for advancing diagnostics, drug discovery, and personalized treatment strategies. We present PhenoGnet, a novel graph-based contrastive learning framework designed to predict disease similarity…

Genomics · Quantitative Biology 2025-09-18 Ranga Baminiwatte , Kazi Jewel Rana , Aaron J. Masino

Matrix factorization methods - including Factor analysis (FA), and Principal Components Analysis (PCA) - are widely used for inferring and summarizing structure in multivariate data. Many matrix factorization methods exist, corresponding to…

Methodology · Statistics 2021-05-04 Wei Wang , Matthew Stephens

In recent years, deep convolutional neural networks (CNN) have significantly advanced face detection. In particular, lightweight CNNbased architectures have achieved great success due to their lowcomplexity structure facilitating real-time…

Computer Vision and Pattern Recognition · Computer Science 2023-02-24 Guangtao Wang , Jun Li , Zhijian Wu , Jianhua Xu , Jifeng Shen , Wankou Yang

Graph neural networks (GNNs) demonstrate great performance in compound property and activity prediction due to their capability to efficiently learn complex molecular graph structures. However, two main limitations persist including…

Biomolecules · Quantitative Biology 2023-10-10 Apakorn Kengkanna , Masahito Ohue

Accurate structural response prediction forms a main driver for structural health monitoring and control applications. This often requires the proposed model to adequately capture the underlying dynamics of complex structural systems. In…

Machine Learning · Computer Science 2023-07-04 Wei Liu , Zhilu Lai , Kiran Bacsa , Eleni Chatzi

Feature construction can contribute to comprehensibility and performance of machine learning models. Unfortunately, it usually requires exhaustive search in the attribute space or time-consuming human involvement to generate meaningful…

Machine Learning · Computer Science 2023-01-24 Boštjan Vouk , Matej Guid , Marko Robnik-Šikonja

In the evolving field of psychopathology, the accurate assessment and forecasting of data derived from Ecological Momentary Assessment (EMA) is crucial. EMA offers contextually-rich psychopathological measurements over time, that…

Machine Learning · Computer Science 2024-03-29 Mandani Ntekouli , Gerasimos Spanakis , Lourens Waldorp , Anne Roefs

Multi-modal neuroimaging technology has greatlly facilitated the efficiency and diagnosis accuracy, which provides complementary information in discovering objective disease biomarkers. Conventional deep learning methods, e.g. convolutional…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Yanwu Yang , Xutao Guo , Zhikai Chang , Chenfei Ye , Yang Xiang , Ting Ma

In a complex disease such as tuberculosis, the evidence for the disease and its evolution may be present in multiple modalities such as clinical, genomic, or imaging data. Effective patient-tailored outcome prediction and therapeutic…

The integration of quantum machine learning with classical deep learning offers promising avenues for medical image analysis by mapping data into high-dimensional Hilbert spaces. However, effectively unifying these distinct paradigms…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Yasmin Rodrigues Sobrinho , João Renato Ribeiro Manesco , João Paulo Papa

Predicting enzyme-substrate interactions has long been a fundamental problem in biochemistry and metabolic engineering. While existing methods could leverage databases of expert-curated enzyme-substrate pairs for models to learn from known…

Artificial Intelligence · Computer Science 2026-01-12 Tengwei Song , Long Yin , Zhen Han , Zhiqiang Xu

Predicting the interaction between a compound and a target is crucial for rapid drug repurposing. Deep learning has been successfully applied in drug-target affinity (DTA) problem. However, previous deep learning-based methods ignore…

Machine Learning · Computer Science 2020-09-29 Tri Minh Nguyen , Thin Nguyen , Thao Minh Le , Truyen Tran

Correctly identifying sleep stages is important in diagnosing and treating sleep disorders. This work proposes a joint classification-and-prediction framework based on CNNs for automatic sleep staging, and, subsequently, introduces a simple…

Machine Learning · Computer Science 2019-02-05 Huy Phan , Fernando Andreotti , Navin Cooray , Oliver Y. Chén , Maarten De Vos