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The self-organization of microbial ecosystems involves a large variety of mechanisms, ranging from biochemical signaling to population dynamics. Among these, the role of motility regulation has been little studied, despite the importance of…

Statistical Mechanics · Physics 2025-03-18 Alberto Dinelli , Ada Altieri , Julien Tailleur

Bacteria regulate their motility through a variety of mechanisms, including quorum sensing (QS) and other density-dependent responses mediated by diffusible signals. While nonlinear density-dependent motility is well known in active-matter…

Populations and Evolution · Quantitative Biology 2026-01-21 Mattia Mattei , David Soriano-Paños , Alex Arenas

Microbes providing public goods are widespread in nature despite running the risk of being exploited by free-riders. However, the precise ecological factors supporting cooperation are still puzzling. Following recent experiments, we…

Populations and Evolution · Quantitative Biology 2012-03-28 Jonas Cremer , Anna Melbinger , Erwin Frey

The intestinal microbiota plays important roles in digestion and resistance against entero-pathogens. As with other ecosystems, its species composition is resilient against small disturbances but strong perturbations such as antibiotics can…

Quantitative Methods · Quantitative Biology 2015-06-04 Vanni Bucci , Serena Bradde , Giulio Biroli , Joao B. Xavier

Here, we study the evolution of specialization using realistic computer simulations of bacteria that secrete two public goods in a dynamic fluid. Through this first principles approach, we find physical factors such as diffusion, flow…

Populations and Evolution · Quantitative Biology 2020-02-03 Gurdip Uppal , Dervis Can Vural

Soil is a complex, dynamic material, with physical properties that depend on its biological content. We propose a cellular automaton model for self-organizing soil structure, where soil aggregates and serves as food for microbial species.…

Biological Physics · Physics 2025-10-10 Riz Fernando Noronha , Kim Sneppen , Kunihiko Kaneko

Culturing cells confined in microscale geometries has been reported in many studies this last decade, in particular following the development of microfluidic-based applications and lab-on-a-chip devices. Such studies usually examine growth…

Immotile microbes inhabit nearly every environment on Earth, from soils and sediments to food matrices -- yet how they disperse through these physically confining environments is poorly understood. Here, we show that immotile microbial…

Numerous experimental studies have demonstrated that the microenvironment is a key regulator influencing the proliferative and migrative potentials of species. Spatial and temporal disturbances lead to adverse and hazardous…

Populations and Evolution · Quantitative Biology 2015-10-07 Venkata. S. K. Manem , Kamran Kaveh , Mohammad Kohandel , Siv Sivaloganathan

Biological systems exhibit large-scale self-organized dynamics and structures which enable organisms to perform the functions of life. The field of active matter strives to develop and understand microscopically-driven nonequilibrium…

Soft Condensed Matter · Physics 2016-02-11 Michael F. Hagan , Aparna Baskaran

The built environment provides an excellent setting for interdisciplinary research on the dynamics of microbial communities. The system is simplified compared to many natural settings, and to some extent the entire environment can be…

Soft surfaces, spanning vastly different environmental and biomedical settings, are frequently colonised by surface-associated bacteria. Yet, how soft surfaces govern bacterial dynamics and their self-organisation into colonies remains…

Biological Physics · Physics 2025-12-29 Garima Rani , G. H. Philipp Nguyen , René Wittmann , Hartmut Löwen , Anupam Sengupta

Microbial ecosystems are remarkably diverse, stable, and often consist of a balanced mixture of core and peripheral species. Here we propose a conceptual model exhibiting all these emergent properties in quantitative agreement with real…

Populations and Evolution · Quantitative Biology 2018-04-18 Akshit Goyal , Sergei Maslov

Self-organization is the generation of order out of local interactions in non-equilibrium [1]. It is deeply connected to all fields of science from physics, chemistry to biology where functional living structures self-assemble[2] and…

Soft Condensed Matter · Physics 2018-10-24 Utsab Khadka , Viktor Holubec , Haw Yang , Frank Cichos

Bioconvection, a phenomenon arising from the collective motion of motile microorganisms, plays a crucial role in shaping microbial distributions, fluid dynamics, and bloom formation in aquatic environments. While extensive research has…

Biological Physics · Physics 2025-04-15 Samarendu Biswas , Sachidananda Mahato , Jayabrata Dhar

How motile bacteria move near a surface is a problem of fundamental biophysical interest and is key to the emergence of several phenomena of biological, ecological and medical relevance, including biofilm formation. Solid boundaries can…

Biological Physics · Physics 2019-09-12 Stanislaw Makarchuk , Vasco C. Braz , Nuno A. M. Araújo , Lena Ciric , Giorgio Volpe

The colonisation of a soft passive material by motile cells such as bacteria is common in biology. The resulting colonies of the invading cells are often observed to exhibit intricate patterns whose morphology and dynamics can depend on a…

Soft Condensed Matter · Physics 2021-01-12 Mohammad Imaran , Mandar Inamdar , Ranganathan Prabhakar , Raghunath Chelakkot

Two species with similar resource requirements respond in a characteristic way to variations in their habitat -- their abundances rise and fall in concert. We use this idea to learn how bacterial populations in the microbiota respond to…

Populations and Evolution · Quantitative Biology 2015-10-02 Charles K. Fisher , Thierry Mora , Aleksandra M. Walczak

Proliferation is a defining feature of life. Through growth, division, and death, living systems consume energy and inject mass, breaking conservation laws and driving collective phenomena from biofilm formation to embryonic development.…

Statistical Mechanics · Physics 2026-03-25 Nicola Pellicciotta , Luca Angelani , Roberto Di Leonardo

We experimentally investigate how aerotactic bacteria, confined within a thin liquid film between two solid substrates, respond to a controlled oxygen gradient. We find that the total bacterial number density dictates which mechanism…

Soft Condensed Matter · Physics 2026-04-07 Minjun Kim , Joonwoo Jeong