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Dynamic functional connectivity (dFC) derived from resting-state functional magnetic resonance imaging (fMRI) has been extensively utilized in brain science research. The sliding window correlation (SWC) method is a widely used approach for…

Neurons and Cognition · Quantitative Biology 2026-03-27 Jinlong Hu , Jiatong Huang , Zijian Cai

An essential premise for neuroscience brain network analysis is the successful segmentation of the cerebral cortex into functionally homogeneous regions. Resting-state functional magnetic resonance imaging (rs-fMRI), capturing the…

Neurons and Cognition · Quantitative Biology 2023-09-20 Xiaoxiao Ma , Chunzhi Yi , Zhicai Zhong , Hui Zhou , Baichun Wei , Haiqi Zhu , Feng Jiang

Brain connectivity analysis is crucial for understanding brain structure and neurological function, shedding light on the mechanisms of mental illness. To study the association between individual brain connectivity networks and the clinical…

While differences in patterns of functional connectivity and neural synchronization have been reported between individuals on the autism spectrum and neurotypical peers at various age stages, these differences appear to be subtle and may…

Neurons and Cognition · Quantitative Biology 2025-07-15 Sungwoo Ahn , Leonid L Rubchinsky , Evie A Malaia

The resting-state brain networks (RSNs) reflects the functional connectivity patterns between brain modules, providing essential foundations for decoding intrinsic neural information within the brain. It serves as one of the primary tools…

Human-Computer Interaction · Computer Science 2025-01-22 Shiang Hu , Xiao Gong , Xiaolong Huang , Jie Ruan , Pedro Antonio Valdes-Sosa

Determining if the brain is developing normally is a key component of pediatric neuroradiology and neurology. Brain magnetic resonance imaging (MRI) of infants demonstrates a specific pattern of development beyond simply myelination. While…

Image and Video Processing · Electrical Eng. & Systems 2021-12-28 Mahdieh Shabanian , Markus Wenzel , John P. DeVincenzo

It has become increasingly popular to study the brain as a network due to the realization that functionality cannot be explained exclusively by independent activation of specialized regions. Instead, across a large spectrum of behaviors,…

Neurons and Cognition · Quantitative Biology 2014-07-22 Petko Bogdanov , Nazli Dereli , Danielle S. Bassett , Scott T. Grafton , Ambuj K. Singh

Background: Non-linear alterations in brain network connectivity may represent early neural signatures of Alzheimer's disease (AD) pathology in cognitively normal older adults. Understanding these changes and their cognitive relevance may…

Neurons and Cognition · Quantitative Biology 2026-04-22 Junjie Wu , Benjamin B Risk , Taylor A James , Nicholas Seyfried , David W Loring , Felicia C Goldstein , Allan I Levey , James J Lah , Deqiang Qiu

Deep brain stimulation (DBS) is a neurosurgical procedure successfully used to treat conditions such as Parkinson's disease. Electrostimulation, carried out by implanting electrodes into an identified focus in the brain, makes it possible…

Signal Processing · Electrical Eng. & Systems 2023-08-23 Arkadiusz Nowacki , Ewelina Kołpa , Mateusz Szychiewicz , Konrad Ciecierski

Brain functional network has become an increasingly used approach in understanding brain functions and diseases. Many network construction methods have been developed, whereas the majority of the studies still used static pairwise Pearson's…

Neurons and Cognition · Quantitative Biology 2020-03-13 Zhen Zhou , Xiaobo Chen , Yu Zhang , Lishan Qiao , Renping Yu , Gang Pan , Han Zhang , Dinggang Shen

Brain responses related to working memory originate from distinct brain areas and oscillate at different frequencies. EEG signals with high temporal correlation can effectively capture these responses. Therefore, estimating the functional…

Machine Learning · Computer Science 2024-05-01 Harshini Gangapuram , Vidya Manian

Diagnosing Autism Spectrum Disorder (ASD) is a challenging problem, and is based purely on behavioral descriptions of symptomology (DSM-5/ICD-10), and requires informants to observe children with disorder across different settings (e.g.…

Neurons and Cognition · Quantitative Biology 2020-03-04 Taban Eslami , Joseph S. Raiker , Fahad Saeed

Brain age estimation based on magnetic resonance imaging (MRI) is an active research area in early diagnosis of some neurodegenerative diseases (e.g. Alzheimer, Parkinson, Huntington, etc.) for elderly people or brain underdevelopment for…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Ruizhe Li , Matteo Bastiani , Dorothee Auer , Christian Wagner , Xin Chen

Building comprehensive brain connectomes has proved of fundamental importance in resting-state fMRI (rs-fMRI) analysis. Based on the foundation of brain network, spatial-temporal-based graph convolutional networks have dramatically improved…

Machine Learning · Computer Science 2023-12-19 Rui Yang , Wenrui Dai , Huajun She , Yiping P. Du , Dapeng Wu , Hongkai Xiong

Autism Spectrum Disorder (ASD) is often underdiagnosed in females due to gender-specific symptom differences overlooked by conventional diagnostics. This study evaluates machine learning models, particularly Random Forest and convolutional…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Mohammed Aledhari , Mohamed Rahouti , Ali Alfatemi

Human brain development is rapid during infancy and early childhood. Many disease processes impair this development. Therefore, brain developmental age estimation (BDAE) is essential for all diseases affecting cognitive development. Brain…

Image and Video Processing · Electrical Eng. & Systems 2019-11-06 Mahdieh Shabanian , Eugene C. Eckstein , Hao Chen , John P. DeVincenzo

Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease. Here we sought to further…

Autism spectrum disorder (ASD) affects the brain connectivity at different levels. Nonetheless, non-invasively distinguishing such effects using magnetic resonance imaging (MRI) remains very challenging to machine learning diagnostic…

Machine Learning · Computer Science 2020-04-29 Ismail Bilgen , Goktug Guvercin , Islem Rekik

Brain disorders in the early and late life of humans potentially share pathological alterations in brain functions. However, the key evidence from neuroimaging data for pathological commonness remains unrevealed. To explore this hypothesis,…

Artificial Intelligence · Computer Science 2023-02-24 Mianxin Liu , Jingyang Zhang , Yao Wang , Yan Zhou , Fang Xie , Qihao Guo , Feng Shi , Han Zhang , Qian Wang , Dinggang Shen

Resting State Networks (RSNs) of the brain extracted from Resting State functional Magnetic Resonance Imaging (RS-fMRI) are used in the pre-surgical planning to guide the neurosurgeon. This is difficult, though, as expert knowledge is…