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Pathology foundation models (PFMs) have demonstrated strong representational capabilities through self-supervised pre-training on large-scale, unannotated histopathology image datasets. However, their diverse yet opaque pretraining…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Yuxiang Xiao , Yang Hu , Bin Li , Tianyang Zhang , Zexi Li , Huazhu Fu , Jens Rittscher , Kaixiang Yang

Multimodal fusion has emerged as a promising paradigm for disease diagnosis and prognosis, integrating complementary information from heterogeneous data sources such as medical images, clinical records, and radiology reports. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Chongyu Qu , Zhengyi Lu , Yuxiang Lai , Thomas Z. Li , Junchao Zhu , Junlin Guo , Juming Xiong , Yanfan Zhu , Yuechen Yang , Allen J. Luna , Kim L. Sandler , Bennett A. Landman , Yuankai Huo

Survival analysis is a fundamental tool for modeling time-to-event outcomes in healthcare. Recent advances have introduced flexible neural network approaches for improved predictive performance. However, most of these models do not provide…

Machine Learning · Statistics 2025-09-10 Mert Ketenci , Vincent Jeanselme , Harry Reyes Nieva , Shalmali Joshi , Noémie Elhadad

Multimodal medical analysis combining image and tabular data has gained increasing attention. However, effective fusion remains challenging due to cross-modal discrepancies in feature dimensions and modality contributions, as well as the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Congjing Yu , Jing Ye , Yang Liu , Xiaodong Zhang , Zhiyong Zhang

Multimodal survival prediction, a crucial yet challenging task, demands the integration of multimodal medical data (\eg Whole Slide Images (WSIs) and Genomic Profiles) to achieve accurate prognostic modeling. Given the inherent…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Huayi Wang , Haochao Ying , Yuyang Xu , Qiyao Zheng , jun wang , Cheng Zhang , Ying Sun , Jian Wu

Multi-modal medical image fusion is essential for the precise clinical diagnosis and surgical navigation since it can merge the complementary information in multi-modalities into a single image. The quality of the fused image depends on the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-25 Xianming Gu , Lihui Wang , Zeyu Deng , Ying Cao , Xingyu Huang , Yue-min Zhu

To improve the prediction of cancer survival using whole-slide images and transcriptomics data, it is crucial to capture both modality-shared and modality-specific information. However, multimodal frameworks often entangle these…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Aniek Eijpe , Soufyan Lakbir , Melis Erdal Cesur , Sara P. Oliveira , Sanne Abeln , Wilson Silva

While multimodal survival prediction models are increasingly more accurate, their complexity often reduces interpretability, limiting insight into how different data sources influence predictions. To address this, we introduce DIMAFx, an…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Aniek Eijpe , Soufyan Lakbir , Melis Erdal Cesur , Sara P. Oliveira , Angelos Chatzimparmpas , Sanne Abeln , Wilson Silva

We propose a novel multimodal deep learning framework for patient-level survival prediction, which integrates whole-slide histology features, RNA-seq expression profiles, and clinical variables. Our architecture combines an ABMIL…

Quantitative Methods · Quantitative Biology 2026-05-15 Hassan Keshvarikhojasteh , Josien P. W. Pluim , Mitko Veta

Multivariate time series forecasting involves predicting future values based on historical observations. However, existing approaches primarily rely on predefined single-scale patches or lack effective mechanisms for multi-scale feature…

Machine Learning · Computer Science 2025-09-24 Huanyao Zhang , Jiaye Lin , Wentao Zhang , Haitao Yuan , Guoliang Li

Hashing plays an important role in information retrieval, due to its low storage and high speed of processing. Among the techniques available in the literature, multi-modal hashing, which can encode heterogeneous multi-modal features into…

Multimedia · Computer Science 2021-08-05 Jun Yu , Donglin Zhang , Zhenqiu Shu , Feng Chen

The use of multi-modal data such as the combination of whole slide images (WSIs) and gene expression data for survival analysis can lead to more accurate survival predictions. Previous multi-modal survival models are not able to efficiently…

Computer Vision and Pattern Recognition · Computer Science 2021-12-09 Ruoqi Wang , Ziwang Huang , Haitao Wang , Hejun Wu

Multimodal Image Fusion (MMIF) aims to integrate complementary information from different imaging modalities to overcome the limitations of individual sensors. It enhances image quality and facilitates downstream applications such as remote…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Mengyu Wang , Zhenyu Liu , Kun Li , Yu Wang , Yuwei Wang , Yanyan Wei , Fei Wang

Survival prediction plays a crucial role in assisting clinicians with the development of cancer treatment protocols. Recent evidence shows that multimodal data can help in the diagnosis of cancer disease and improve survival prediction.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ruiquan Ge , Xiangyang Hu , Rungen Huang , Gangyong Jia , Yaqi Wang , Renshu Gu , Changmiao Wang , Elazab Ahmed , Linyan Wang , Juan Ye , Ye Li

Feature selection is essential for high-dimensional biomedical data, enabling stronger predictive performance, reduced computational cost, and improved interpretability in precision medicine applications. Existing approaches face notable…

Machine Learning · Computer Science 2026-01-07 Xiaoyan Sun , Qingyu Meng , Yalu Wen

Developing effective multimodal data fusion strategies has become increasingly essential for improving the predictive power of statistical machine learning methods across a wide range of applications, from autonomous driving to medical…

Machine Learning · Computer Science 2025-07-29 Ziyi Liang , Annie Qu , Babak Shahbaba

Multimodal high-dimensional data are increasingly prevalent in biomedical research, yet they are often compromised by block-wise missingness and measurement errors, posing significant challenges for statistical inference and prediction. We…

Cross-modal hashing is an important approach for multimodal data management and application. Existing unsupervised cross-modal hashing algorithms mainly rely on data features in pre-trained models to mine their similarity relationships.…

Information Retrieval · Computer Science 2022-07-12 Liang Li , Baihua Zheng , Weiwei Sun

This study introduces a novel multimodal food recognition framework that effectively combines visual and textual modalities to enhance classification accuracy and robustness. The proposed approach employs a dynamic multimodal fusion…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Prateek Mittal , Puneet Goyal , Joohi Chauhan

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood
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