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Recently, the study of graph neural network (GNN) has attracted much attention and achieved promising performance in molecular property prediction. Most GNNs for molecular property prediction are proposed based on the idea of learning the…

Machine Learning · Computer Science 2021-04-15 Yingfang Yuan , Wenjun Wang , Wei Pang

Despite the biological importance of non-coding RNA, their structural characterization remains challenging. Making use of the rapidly growing sequence databases, we analyze nucleotide coevolution across homologous sequences via…

Biomolecules · Quantitative Biology 2015-10-13 Eleonora De Leonardis , Benjamin Lutz , Sebastian Ratz , Simona Cocco , Remi Monasson , Alexander Schug , Martin Weigt

Neural networks are capable of learning powerful representations of data, but they are susceptible to overfitting due to the number of parameters. This is particularly challenging in the domain of time series classification, where datasets…

Machine Learning · Computer Science 2022-01-28 Hong Yang , Travis Desell

This study proposes a new framework to evolve efficacious yet parsimonious neural architectures for the movement prediction of stock market indices using technical indicators as inputs. In the light of a sparse signal-to-noise ratio under…

Neural and Evolutionary Computing · Computer Science 2021-11-17 Faizal Hafiz , Jan Broekaert , Davide La Torre , Akshya Swain

The PHASE software package allows phylogenetic tree construction with a number of evolutionary models designed specifically for use with RNA sequences that have conserved secondary structure. Evolution in the paired regions of RNAs occurs…

Populations and Evolution · Quantitative Biology 2007-05-23 Cendrine Hudelot , Vivek Gowri-Shankar , Howsun Jow , Magnus Rattray , Paul G. Higgs

Iterative methods for fitting a Gaussian Random Field (GRF) model via maximum likelihood (ML) estimation requires solving a nonconvex optimization problem. The problem is aggravated for anisotropic GRFs where the number of covariance…

Machine Learning · Statistics 2021-01-12 Sam Davanloo Tajbakhsh , Necdet Serhat Aybat , Enrique Del Castillo

RNA structure prediction is a challenging problem, especially with pseudoknots. Recently, there has been a shift from the classical minimum free energy-based methods (MFE) to partition function-based ones that assemble structures using…

Biomolecules · Quantitative Biology 2020-01-10 Liang Zhang , He Zhang , David H. Mathews , Liang Huang

We present a deep learning framework, called DuLa-Net, to predict Manhattan-world 3D room layouts from a single RGB panorama. To achieve better prediction accuracy, our method leverages two projections of the panorama at once, namely the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-03 Shang-Ta Yang , Fu-En Wang , Chi-Han Peng , Peter Wonka , Min Sun , Hung-Kuo Chu

The measurement of the similarity of RNA secondary structures, and in general of contact structures, of a fixed length has several specific applications. For instance, it is used in the analysis of the ensemble of suboptimal secondary…

Discrete Mathematics · Computer Science 2007-05-23 Mercé Llabrés , Francesc Rosselló

We propose an optimized parameter set for protein secondary structure prediction using three layer feed forward back propagation neural network. The methodology uses four parameters viz. encoding scheme, window size, number of neurons in…

Biomolecules · Quantitative Biology 2018-02-02 Jyotshna Dongardivev , Siby Abraham

Artificial neural networks (ANNs) are powerful tools capable of approximating any arbitrary mathematical function, but their interpretability remains limited, rendering them as black box models. To address this issue, numerous methods have…

Machine Learning · Computer Science 2024-06-11 Abhiram Anand Thiruthummal , Eun-jin Kim , Sergiy Shelyag

Binary neural networks have attracted tremendous attention due to the efficiency for deploying them on mobile devices. Since the weak expression ability of binary weights and features, their accuracy is usually much lower than that of…

Machine Learning · Computer Science 2019-09-18 Mingzhu Shen , Kai Han , Chunjing Xu , Yunhe Wang

With the development of sixth generation (6G) networks toward digitalization and intelligentization of communications, rapid and precise channel prediction is crucial for the network potential release. Interestingly, a dynamic ray tracing…

Signal Processing · Electrical Eng. & Systems 2024-05-07 Yinghe Miao , Li Yu , Yuxiang Zhang , Hongbo Xing , Jianhua Zhang

The three-dimensional conformations of non-coding RNAs underpin their biochemical functions but have largely eluded experimental characterization. Here, we report that integrating a classic mutation/rescue strategy with high-throughput…

Biomolecules · Quantitative Biology 2015-06-09 Siqi Tian , Pablo Cordero , Wipapat Kladwang , Rhiju Das

Motivation: Non-coding RNAs (ncRNAs) express their functions by adopting molecular structures. Specifically, RNA secondary structures serve as a relatively stable intermediate step before tertiary structures, offering a reliable signature…

Data Structures and Algorithms · Computer Science 2024-02-07 Bertrand Marchand , Yoann Anselmetti , Manuel Lafond , Aïda Ouangraoua

Effective analysis in neuroscience benefits significantly from robust conceptual frameworks. Traditional metrics of interbrain synchrony in social neuroscience typically depend on fixed, correlation-based approaches, restricting their…

Neurons and Cognition · Quantitative Biology 2025-12-01 Nicolás Hinrichs , Noah Guzmán , Melanie Weber

Gene expression analysis aims at identifying the genes able to accurately predict biological parameters like, for example, disease subtyping or progression. While accurate prediction can be achieved by means of many different techniques,…

Methodology · Statistics 2008-09-11 Christine De Mol , Sofia Mosci , Magali Traskine , Alessandro Verri

Combinatorial analysis of a certain abstract of RNA structures has been studied to investigate their statistics. Our approach regards the backbone of secondary structures as an alternate sequence of paired and unpaired sets of nucleotides,…

Quantitative Methods · Quantitative Biology 2020-03-10 Sang Kwan Choi , Chaiho Rim , Hwajin Um

Structural features are important features in a geometrical graph. Although there are some correlation analysis of features based on covariance, there is no relevant research on structural feature correlation analysis with graph neural…

Machine Learning · Computer Science 2022-05-03 Jiaqing Xie , Rex Ying

We investigate the addition of symmetry and temporal context information to a deep Convolutional Neural Network (CNN) with the purpose of detecting malignant soft tissue lesions in mammography. We employ a simple linear mapping that takes…

Computer Vision and Pattern Recognition · Computer Science 2017-08-02 Thijs Kooi , Nico Karssemeijer
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