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Related papers: Clean & Clear: Feasibility of Safe LLM Clinical Gu…

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Clinical calculators are widely used, and large language models (LLMs) make it possible to engage them using natural language. We demonstrate a purpose-built chatbot that leverages software implementations of verifiable clinical calculators…

Quantitative Methods · Quantitative Biology 2025-03-25 Niranjan Kumar , Farid Seifi , Marisa Conte , Allen Flynn

Millions of patients are already using large language model (LLM) chatbots for medical advice on a regular basis, raising patient safety concerns. This physician-led red-teaming study compares the safety of four publicly available…

The ability to provide trustworthy maternal health information using phone-based chatbots can have a significant impact, particularly in low-resource settings where users have low health literacy and limited access to care. However,…

Objective: This study aims to develop and validate an evaluation framework to ensure the safety and reliability of mental health chatbots, which are increasingly popular due to their accessibility, human-like interactions, and context-aware…

LLMs promise to overcome limitations of rule-based mental health chatbots through improved natural language capabilities, yet their ability to deliver evidence-based psychological interventions remains largely unverified because evaluations…

Human-Computer Interaction · Computer Science 2025-12-22 Florian Onur Kuhlmeier , Leon Hanschmann , Melina Rabe , Stefan Luettke , Eva-Lotta Brakemeier , Alexander Maedche

The integration of Large Language Models (LLMs) into healthcare settings has gained significant attention, particularly for question-answering tasks. Given the high-stakes nature of healthcare, it is essential to ensure that LLM-generated…

Lab results are often confusing and hard to understand. Large language models (LLMs) such as ChatGPT have opened a promising avenue for patients to get their questions answered. We aim to assess the feasibility of using LLMs to generate…

Computation and Language · Computer Science 2024-04-23 Zhe He , Balu Bhasuran , Qiao Jin , Shubo Tian , Karim Hanna , Cindy Shavor , Lisbeth Garcia Arguello , Patrick Murray , Zhiyong Lu

Student commitment towards a learning recommendation is not separable from their understanding of the reasons it was recommended to them; and their ability to modify it based on that understanding. Among explainability approaches, chatbots…

Artificial Intelligence · Computer Science 2024-01-25 Hasan Abu-Rasheed , Mohamad Hussam Abdulsalam , Christian Weber , Madjid Fathi

Healthcare systems around the world are grappling with issues like inefficient diagnostics, rising costs, and limited access to specialists. These problems often lead to delays in treatment and poor health outcomes. Most current AI and deep…

Artificial Intelligence · Computer Science 2025-12-22 Maliha Tabassum , M Shamim Kaiser

Domain specific large language models are increasingly used to support patient education, triage, and clinical decision making in ophthalmology, making rigorous evaluation essential to ensure safety and accuracy. This study evaluated four…

Recent research has shown that hallucinations, omissions, and biases are prevalent in everyday use-cases of LLMs. However, chatbots used in medical contexts must provide consistent advice in situations where non-medical factors are…

Computation and Language · Computer Science 2025-11-05 Jonathan Liu , Haoling Qiu , Jonathan Lasko , Damianos Karakos , Mahsa Yarmohammadi , Mark Dredze

When applied directly in an end-to-end manner to medical follow-up tasks, Large Language Models (LLMs) often suffer from uncontrolled dialog flow and inaccurate information extraction due to the complexity of follow-up forms. To address…

Computation and Language · Computer Science 2025-12-23 Jinyan Liu , Zikang Chen , Qinchuan Wang , Tan Xie , Heming Zheng , Xudong Lv

The increasing trust in large language models (LLMs), especially in the form of chatbots, is often undermined by the lack of their extrinsic evaluation. This holds particularly true in nutrition, where randomised controlled trials (RCTs)…

Human-Computer Interaction · Computer Science 2025-11-27 Karen Jia-Hui Li , Simone Balloccu , Ondrej Dusek , Ehud Reiter

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

Computation and Language · Computer Science 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo

Large language models (LLMs) are increasingly used for mental-health support; yet prevailing evaluation methods--fluency metrics, preference tests, and generic dialogue benchmarks--fail to capture the clinically critical dimensions of…

Computation and Language · Computer Science 2026-03-20 Fangrui Huang , Souhad Chbeir , Arpandeep Khatua , Sheng Wang , Sijun Tan , Kenan Ye , Lily Bailey , Merryn Daniel , Ryan Louie , Sanmi Koyejo , Ehsan Adeli

The primary aim of this research was to address the limitations observed in the medical knowledge of prevalent large language models (LLMs) such as ChatGPT, by creating a specialized language model with enhanced accuracy in medical advice.…

Computation and Language · Computer Science 2023-06-27 Yunxiang Li , Zihan Li , Kai Zhang , Ruilong Dan , Steve Jiang , You Zhang

With the introduction of ChatGPT, Large Language Models (LLMs) have received enormous attention in healthcare. Despite their potential benefits, researchers have underscored various ethical implications. While individual instances have…

Computers and Society · Computer Science 2024-07-09 Joschka Haltaufderheide , Robert Ranisch

Purpose: To assess the alignment of GPT-4-based evaluation to human clinician experts, for the evaluation of responses to ophthalmology-related patient queries generated by fine-tuned LLM chatbots. Methods: 400 ophthalmology questions and…

Artificial Intelligence · Computer Science 2024-02-16 Ting Fang Tan , Kabilan Elangovan , Liyuan Jin , Yao Jie , Li Yong , Joshua Lim , Stanley Poh , Wei Yan Ng , Daniel Lim , Yuhe Ke , Nan Liu , Daniel Shu Wei Ting

The remarkable capabilities of Large Language Models (LLMs) make them increasingly compelling for adoption in real-world healthcare applications. However, the risks associated with using LLMs in medical applications have not been…

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