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Constraint-based modeling has been widely used on metabolic networks analysis, such as biosynthetic prediction and flux optimization. The linear constraints, like mass conservation constraint, reversibility constraint, biological capacity…

Other Quantitative Biology · Quantitative Biology 2009-11-29 Lu Xie , Yi Zhang

Given the growing concern of reducing CO2 emissions, it is desirable to identify, for a given separation carried out through a membrane cascade, the optimum design that yields the lowest energy consumption. Nevertheless, designing a…

Optimization and Control · Mathematics 2021-02-11 Jose Adrian Chavez Velasco , Radhakrishna Tumbalam Gooty , Mohit Tawarmalani , Rakesh Agrawal

The discrete unit commitment problem with min-stop ramping constraints optimizes the daily production of thermal power plants (coal, gas, fuel units). For this problem, compact Integer Linear Programming (ILP) formulations have been…

Optimization and Control · Mathematics 2019-12-21 Nicolas Dupin

Identifying discrete patterns in binary data is an important dimensionality reduction tool in machine learning and data mining. In this paper, we consider the problem of low-rank binary matrix factorisation (BMF) under Boolean arithmetic.…

Optimization and Control · Mathematics 2021-08-05 Reka A. Kovacs , Oktay Gunluk , Raphael A. Hauser

In this paper, we consider the problem of preamble design in multiple-input multiple-output (MIMO) systems employing offset quadrature amplitude modulation based filter bank multicarrier (OQAM/FBMC) and propose a preamble optimization…

Information Theory · Computer Science 2018-02-13 Wenfeng Liu , Da Chen , Kai Luo , Tao Jiang , Daiming Qu

Recently, it has become evident that submodularity naturally captures widely occurring concepts in machine learning, signal processing and computer vision. Consequently, there is need for efficient optimization procedures for submodular…

Machine Learning · Computer Science 2013-11-19 Stefanie Jegelka , Francis Bach , Suvrit Sra

An efficient framework is conceived for fractional matrix programming (FMP) optimization problems (OPs) namely for minimization and maximization. In each generic OP, either the objective or the constraints are functions of multiple…

Signal Processing · Electrical Eng. & Systems 2025-07-15 Mohammad Soleymani , Eduard Jorswieck , Robert Schober , Lajos Hanzo

Multi-term floating-point addition appears in vector dot-product computations, matrix multiplications, and other forms of floating-point data aggregation. A critical step in multi-term floating point addition is the alignment of fractions…

Hardware Architecture · Computer Science 2024-10-30 Kosmas Alexandridis , Giorgos Dimitrakopoulos

Many regression problems involve not one but several response variables (y's). Often the responses are suspected to share a common underlying structure, in which case it may be advantageous to share information across them; this is known as…

Machine Learning · Computer Science 2009-06-02 Brian Tomasik

In many real-world applications, from robotics to pedestrian trajectory prediction, there is a need to predict multiple real-valued outputs to represent several potential scenarios. Current deep learning techniques to address…

Machine Learning · Computer Science 2023-12-20 David D. Nguyen , David Liebowitz , Surya Nepal , Salil S. Kanhere

The study of phenomena such as protein folding and conformational changes in molecules is a central theme in chemical physics. Molecular dynamics (MD) simulation is the primary tool for the study of transition processes in biomolecules, but…

Computational Physics · Physics 2022-12-14 Luke Evans , Maria K. Cameron , Pratyush Tiwary

We propose a learning algorithm to design a light-weight neural multiplexer that given the input and computational resource requirements, calls the model that will consume the minimum compute resources for a successful inference. Mobile…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-09-18 Amir Erfan Eshratifar , Massoud Pedram

Mismatch cost (MMC) is a universally applicable lower bound on the entropy production (EP) of any fixed physical process across a given time interval. In the first part of the paper, we establish results concerning MMC to prove that it…

Statistical Mechanics · Physics 2026-04-27 Abhishek Yadav , Francesco Caravelli , David Wolpert

We study minimax optimal reinforcement learning in episodic factored Markov decision processes (FMDPs), which are MDPs with conditionally independent transition components. Assuming the factorization is known, we propose two model-based…

Machine Learning · Computer Science 2020-06-25 Yi Tian , Jian Qian , Suvrit Sra

This paper introduces a novel algorithm combination designed for fast one-to-many multicriteria shortest path search. A preprocessing algorithm excludes irrelevant vertices by building a smaller cover graph. A modified version of…

Data Structures and Algorithms · Computer Science 2022-02-01 Temirlan Kurbanov , Marek Cuchý , Jiří Vokřínek

We propose a multi-index algorithm for the Monte Carlo (MC) discretization of a linear, elliptic PDE with affine-parametric input. We prove an error vs. work analysis which allows a multi-level finite-element approximation in the physical…

Numerical Analysis · Mathematics 2019-07-18 Josef Dick , Michael Feischl , Christoph Schwab

Version identification systems aim to detect different renditions of the same underlying musical composition (loosely called cover songs). By learning to encode entire recordings into plain vector embeddings, recent systems have made…

Sound · Computer Science 2020-10-08 Furkan Yesiler , Joan Serrà , Emilia Gómez

Dirichlet Process Mixture Models (DPMMs) are widely used to address clustering problems. Their main advantage lies in their ability to automatically estimate the number of clusters during the inference process through the Bayesian…

Machine Learning · Statistics 2023-12-19 Reda Khoufache , Mustapha Lebbah , Hanene Azzag , Etienne Goffinet , Djamel Bouchaffra

Fixed-node diffusion Monte Carlo (DMC) is a stochastic algorithm for finding the lowest energy many-fermion wave function with the same nodal surface as a chosen trial function. It has proved itself among the most accurate methods available…

Condensed Matter · Physics 2009-10-31 W. M. C. Foulkes , Randolph Q. Hood , R. J. Needs

This article presents the first mixed-integer linear programming (MILP)-based iterative algorithm to solve factorable mixed-integer nonlinear programs (MINLPs) with bounded, differentiable periodic functions to global optimality with an…

Optimization and Control · Mathematics 2025-10-01 Christopher Montez , Sujeevraja Sanjeevi , Kaarthik Sundar