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Optimal designs are usually model-dependent and likely to be sub-optimal if the postulated model is not correctly specified. In practice, it is common that a researcher has a list of candidate models at hand and a design has to be found…

Statistics Theory · Mathematics 2023-03-29 Mingyao Ai , Holger Dette , Zhengfu Liu , Jun Yu

Recent advances in machine learning make it possible to design efficient prediction algorithms for data sets with huge numbers of parameters. This paper describes a new technique for "hedging" the predictions output by many such algorithms,…

Machine Learning · Computer Science 2011-11-22 Alexander Gammerman , Vladimir Vovk

We review algorithms for protein design in general. Although these algorithms have a rich combinatorial, geometric, and mathematical structure, they are almost never covered in computer science classes. Furthermore, many of these algorithms…

Computational Engineering, Finance, and Science · Computer Science 2019-10-01 Mark A. Hallen , Bruce R. Donald

The increasing popularity of deep learning models has created new opportunities for developing AI-based recommender systems. Designing recommender systems using deep neural networks requires careful architecture design, and further…

Information Retrieval · Computer Science 2024-11-13 Tunhou Zhang , Dehua Cheng , Yuchen He , Zhengxing Chen , Xiaoliang Dai , Liang Xiong , Yudong Liu , Feng Cheng , Yufan Cao , Feng Yan , Hai Li , Yiran Chen , Wei Wen

The ability to design and optimize biological sequences with specific functionalities would unlock enormous value in technology and healthcare. In recent years, machine learning-guided sequence design has progressed this goal significantly,…

Quantitative Methods · Quantitative Biology 2022-11-21 Lauren Berk Wheelock , Stephen Malina , Jeffrey Gerold , Sam Sinai

As the number of applications that use machine learning algorithms increases, the need for labeled data useful for training such algorithms intensifies. Getting labels typically involves employing humans to do the annotation, which directly…

Machine Learning · Computer Science 2013-07-16 Alexandros Ntoulas , Omar Alonso , Vasilis Kandylas

We study the task of teaching a machine to classify objects using features and labels. We introduce the Error-Driven-Featuring design pattern for teaching using features and labels in which a teacher prefers to introduce features only if…

Artificial Intelligence · Computer Science 2016-11-21 Christopher Meek , Patrice Simard , Xiaojin Zhu

There is a growing concern about typically opaque decision-making with high-performance machine learning algorithms. Providing an explanation of the reasoning process in domain-specific terms can be crucial for adoption in risk-sensitive…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Aditya Chattopadhyay , Stewart Slocum , Benjamin D. Haeffele , Rene Vidal , Donald Geman

Classification is an important task in many fields including biomedical research and machine learning. Traditionally, a classification rule is constructed based a bunch of labeled data. Recently, due to technological innovation and…

Methodology · Statistics 2014-06-19 Jing Wang , Eunsik Park , Yuan-chin Ivan Chang

Most design methods contain a forward framework, asking for primary specifications of a building to generate an output or assess its performance. However, architects urge for specific objectives though uncertain of the proper design…

Computer Vision and Pattern Recognition · Computer Science 2021-06-10 Zohreh Shaghaghian , Wei Yan

Plant breeding programs use data obtained from multi-environment selection experiments to produce improved varieties with the ultimate aim of maintaining high levels of genetic gain. Selection accuracy can be improved with the use of…

Methodology · Statistics 2026-05-13 Brian R Cullis , Alison B Smith , David GD Hughes , David Butler

Efficient algorithms for searching for optimal saturated designs are widely available. They maximize a given efficiency measure (such as D-optimality) and provide an optimum design. Nevertheless, they do not guarantee a \emph{global}…

Computation · Statistics 2013-03-29 Roberto Fontana

A burgeoning paradigm in algorithm design is the field of algorithms with predictions, in which algorithms can take advantage of a possibly-imperfect prediction of some aspect of the problem. While much work has focused on using predictions…

Machine Learning · Computer Science 2022-10-18 Mikhail Khodak , Maria-Florina Balcan , Ameet Talwalkar , Sergei Vassilvitskii

Proteins perform critical processes in all living systems: converting solar energy into chemical energy, replicating DNA, as the basis of highly performant materials, sensing and much more. While an incredible range of functionality has…

Biomolecules · Quantitative Biology 2021-09-29 Leonardo V. Castorina , Rokas Petrenas , Kartic Subr , Christopher W. Wood

Efficient deep learning computing requires algorithm and hardware co-design to enable specialization: we usually need to change the algorithm to reduce memory footprint and improve energy efficiency. However, the extra degree of freedom…

Machine Learning · Computer Science 2019-04-25 Song Han , Han Cai , Ligeng Zhu , Ji Lin , Kuan Wang , Zhijian Liu , Yujun Lin

Machine learning-based design has gained traction in the sciences, most notably in the design of small molecules, materials, and proteins, with societal implications spanning drug development and manufacturing, plastic degradation, and…

Machine Learning · Computer Science 2025-04-04 Clara Fannjiang , Jennifer Listgarten

Algorithm design is a laborious process and often requires many iterations of ideation and validation. In this paper, we explore automating algorithm design and present a method to learn an optimization algorithm, which we believe to be the…

Machine Learning · Computer Science 2016-06-07 Ke Li , Jitendra Malik

Our work revisits the design of mechanisms via the learning-augmented framework. In this model, the algorithm is enhanced with imperfect (machine-learned) information concerning the input, usually referred to as prediction. The goal is to…

Computer Science and Game Theory · Computer Science 2024-10-29 George Christodoulou , Alkmini Sgouritsa , Ioannis Vlachos

Prediction-oriented machine learning is becoming increasingly valuable to organizations, as it may drive applications in crucial business areas. However, decision-makers from companies across various industries are still largely reluctant…

Software Engineering · Computer Science 2023-06-22 Giacomo Welsch , Peter Kowalczyk

Recommender systems present a customized list of items based upon user or item characteristics with the objective of reducing a large number of possible choices to a smaller ranked set most likely to appeal to the user. A variety of…

Information Retrieval · Computer Science 2024-07-02 William Noffsinger
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