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Variational Quantum Algorithms (VQAs) are relatively robust to noise, but errors are still a significant detriment to VQAs on near-term quantum machines. It is imperative to employ error mitigation techniques to improve VQA fidelity. While…

Optimization problems are critical across various domains, yet existing quantum algorithms, despite their great potential, struggle with scalability and accuracy due to excessive reliance on entanglement. To address these limitations, we…

Quantum Physics · Physics 2025-03-04 Seongmin Kim , In-Saeng Suh

Quantum heuristics have shown promise in solving various optimization problems, including lattice protein folding. Equally relevant is the inverse problem, protein design, where one seeks sequences that fold to a given target structure. The…

Quantum computing has made significant advancements in the last years in both hardware and software. Unfortunately, the currently available Noisy Intermediate-Scale Quantum (NISQ) hardware is still heavily affected by noise. Many…

Quantum Physics · Physics 2025-09-04 Tobias Forster , Nils Quetschlich , Robert Wille

The variational quantum eigensolver (VQE) is a hybrid quantum-classical variational algorithm that produces an upper-bound estimate of the ground-state energy of a Hamiltonian. As quantum computers become more powerful and go beyond the…

State-of-the-art noisy digital quantum computers can only execute short-depth quantum circuits. Variational algorithms are a promising route to unlock the potential of noisy quantum computers since the depth of the corresponding circuits…

Solving electronic structure problems is considered one of the most promising applications of quantum computing. However, due to limitations imposed by the coherence time of qubits in the Noisy Intermediate Scale Quantum (NISQ) era or the…

Quantum Physics · Physics 2025-03-20 Shuo Sun , Chandan Kumar , Kevin Shen , Elvira Shishenina , Christian B. Mendl

Variational Quantum Algorithms (VQAs) are a promising approach to leverage Noisy Intermediate-Scale Quantum (NISQ) computers. However, choosing optimal quantum circuits that efficiently solve a given VQA problem is a non-trivial task.…

Quantum Physics · Physics 2025-10-07 Swagat Kumar , Jan-Nico Zaech , Colin Michael Wilmott , Luc Van Gool

Quantum sensing is an important application of emerging quantum technologies. We explore whether a hybrid system of quantum sensors and quantum circuits can surpass the classical limit of sensing. In particular, we use optimization…

Quantum variational algorithms have garnered significant interest recently, due to their feasibility of being implemented and tested on noisy intermediate scale quantum (NISQ) devices. We examine the robustness of the quantum approximate…

Quantum Physics · Physics 2019-11-05 Yulong Dong , Xiang Meng , Lin Lin , Robert Kosut , K. Birgitta Whaley

Quantum circuit optimization - the process of transforming a quantum circuit into an equivalent one with reduced time and space requirements - is crucial for maximizing the utility of current and near-future quantum devices. While most…

Quantum Physics · Physics 2026-01-23 Marcin Szyniszewski , Aleks Kissinger , Noah Linden , Paul Skrzypczyk

Variational quantum algorithms (VQAs) are the quantum analog of classical neural networks (NNs). A VQA consists of a parameterized quantum circuit (PQC) which is composed of multiple layers of ansatzes (simpler PQCs, which are an analogy of…

Quantum Physics · Physics 2022-08-25 Afrad Basheer , Yuan Feng , Christopher Ferrie , Sanjiang Li

Recent works have demonstrated that large quantum circuits can be cut and decomposed into smaller clusters of quantum circuits with fewer qubits that can be executed independently on a small quantum computer. Classical post-processing then…

Quantum Physics · Physics 2022-11-15 Gideon Uchehara , Tor M. Aamodt , Olivia Di Matteo

Quantum computing (QC) is a new paradigm offering the potential of exponential speedups over classical computing for certain computational problems. Each additional qubit doubles the size of the computational state space available to a QC…

Quantum Physics · Physics 2021-03-22 Wei Tang , Teague Tomesh , Martin Suchara , Jeffrey Larson , Margaret Martonosi

With the advent of hybrid quantum classical algorithms using parameterized quantum circuits the question of how to optimize these algorithms and circuits emerges. In this paper we show that the number of single-qubit rotations in…

Quantum Physics · Physics 2020-10-29 S. E. Rasmussen , N. J. S. Loft , T. Bækkegaard , M. Kues , N. T. Zinner

Near term quantum computers suffer from the presence of different noise sources. In order to mitigate for this effect and acquire results with significantly better accuracy, there is the urge of designing efficient error correction or error…

Variational quantum circuits (VQCs) have shown great potential in near-term applications. However, the discriminative power of a VQC, in connection to its circuit architecture and depth, is not understood. To unleash the genuine…

Quantum Physics · Physics 2021-07-19 Bingzhi Zhang , Quntao Zhuang

Quantum circuit simulation is crucial for the development of quantum algorithms, particularly given the high cost and noise limitations of physical quantum hardware. While full-state quantum circuit simulation is commonly employed for…

Quantum Physics · Physics 2026-04-15 Chuan-Chi Wang , Yan-Jie Wang , Chia-Heng Tu , Shih-Hao Hung

We introduce hybrid sequential quantum computing (HSQC), a paradigm for combinatorial optimization that systematically integrates classical and quantum methods within a structured, stage-wise workflow. HSQC may involve an arbitrary sequence…

Variational quantum algorithms are a class of techniques intended to be used on near-term quantum computers. The goal of these algorithms is to perform large quantum computations by breaking the problem down into a large number of shallow…

Quantum Physics · Physics 2023-03-24 Ryan Shaffer , Lucas Kocia , Mohan Sarovar