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Fusing multi-modal data can improve the performance of deep learning models. However, missing modalities are common for medical data due to patients' specificity, which is detrimental to the performance of multi-modal models in…

Image and Video Processing · Electrical Eng. & Systems 2023-09-28 Muyu Wang , Shiyu Fan , Yichen Li , Hui Chen

Emotion recognition plays a vital role in enhancing human-computer interaction. In this study, we tackle the MER-SEMI challenge of the MER2025 competition by proposing a novel multimodal emotion recognition framework. To address the issue…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Juewen Hu , Yexin Li , Jiulin Li , Shuo Chen , Pring Wong

Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…

Neurons and Cognition · Quantitative Biology 2025-04-24 Zhenguang Zhong , Zhixuan Wang

Depression is one of the leading causes of disability worldwide, posing a severe burden on individuals, healthcare systems, and society at large. Recent advancements in Large Language Models (LLMs) have shown promise in addressing mental…

Computation and Language · Computer Science 2025-02-11 Shiyu Teng , Jiaqing Liu , Rahul Kumar Jain , Shurong Chai , Ruibo Hou , Tomoko Tateyama , Lanfen Lin , Yen-wei Chen

This paper presents our approach to the first Multimodal Personality-Aware Depression Detection Challenge, focusing on multimodal depression detection using machine learning and deep learning models. We explore and compare the performance…

Computation and Language · Computer Science 2025-08-29 Javier Si Zhao Hong , Timothy Zoe Delaya , Sherwyn Chan Yin Kit , Pai Chet Ng , Xiaoxiao Miao

Deep learning has proven to be a highly effective tool for a wide range of applications, significantly when leveraging the power of multi-loss functions to optimize performance on multiple criteria simultaneously. However, optimal selection…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Amin Golnari , Mostafa Diba

In recent years, there has been a notable increase in the use of supervised detection methods of major depressive disorder (MDD) based on electroencephalogram (EEG) signals. However, the process of labeling MDD remains challenging. As a…

Machine Learning · Computer Science 2025-12-17 Li-Xuan Zhao , Chen-Yang Xu , Wen-Qiang Li , Bo Wang , Rong-Xing Wei , Qing-Hao Menga

To improve the prediction of cancer survival using whole-slide images and transcriptomics data, it is crucial to capture both modality-shared and modality-specific information. However, multimodal frameworks often entangle these…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Aniek Eijpe , Soufyan Lakbir , Melis Erdal Cesur , Sara P. Oliveira , Sanne Abeln , Wilson Silva

Depression, as a typical mental disorder, has become a prevalent issue significantly impacting public health. However, the prevention and treatment of depression still face multiple challenges, including complex diagnostic procedures,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yu Luo , Nan Huang , Sophie Yu , Hendry Xu , Jerry Wang , Colin Wang , Zhichao Liu , Chen Zeng

Depression is a widespread mental health disorder, yet its automatic detection remains challenging. Prior work has explored unimodal and multimodal approaches, with multimodal systems showing promise by leveraging complementary signals.…

Artificial Intelligence · Computer Science 2026-03-24 Annisaa Fitri Nurfidausi , Eleonora Mancini , Paolo Torroni

Multimodal deep learning (MDL) has emerged as a transformative approach in computational pathology. By integrating complementary information from multiple data sources, MDL models have demonstrated superior predictive performance across…

Quantitative Methods · Quantitative Biology 2025-11-17 Seth Alain Chang , Muhammad Mueez Amjad , Noorul Wahab , Ethar Alzaid , Nasir Rajpoot , Adam Shephard

Depression is a serious mental illness that impacts the way people communicate, especially through their emotions, and, allegedly, the way they interact with others. This work examines depression signals in dialogs, a less studied setting…

Computation and Language · Computer Science 2022-08-23 Chuyuan Li , Chloé Braud , Maxime Amblard

Current diagnostic practice in psychiatry is not relying on objective biophysical evidence. Recent pandemic emphasized the need to address the rising number of mood disorders (in particular, depression) cases in a more efficient way. We are…

Neurons and Cognition · Quantitative Biology 2021-10-26 Milena B. Čukić

Depression is increasingly impacting individuals both physically and psychologically worldwide. It has become a global major public health problem and attracts attention from various research fields. Traditionally, the diagnosis of…

Human-Computer Interaction · Computer Science 2022-02-28 Kaining Mao , Wei Zhang , Deborah Baofeng Wang , Ang Li , Rongqi Jiao , Yanhui Zhu , Bin Wu , Tiansheng Zheng , Lei Qian , Wei Lyu , Minjie Ye , Jie Chen

Sentiment analysis, mostly based on text, has been rapidly developing in the last decade and has attracted widespread attention in both academia and industry. However, the information in the real world usually comes from multiple…

Computation and Language · Computer Science 2019-12-12 Feiyang Chen , Ziqian Luo , Yanyan Xu , Dengfeng Ke

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

The utilization of automated depression detection significantly enhances early intervention for individuals experiencing depression. Despite numerous proposals on automated depression detection using recorded clinical interview videos,…

Artificial Intelligence · Computer Science 2024-08-08 Juho Jung , Chaewon Kang , Jeewoo Yoon , Seungbae Kim , Jinyoung Han

Accurate survival prediction in Non-Small Cell Lung Cancer (NSCLC) requires integrating clinical, radiological, and histopathological data. Multimodal Deep Learning (MDL) can improve precision prognosis, but small cohorts and missing…

Speech is a noninvasive digital phenotype that can offer valuable insights into mental health conditions, but it is often treated as a single modality. In contrast, we propose the treatment of patient speech data as a trimodal multimedia…

Computation and Language · Computer Science 2025-07-24 Mai Ali , Christopher Lucasius , Tanmay P. Patel , Madison Aitken , Jacob Vorstman , Peter Szatmari , Marco Battaglia , Deepa Kundur

Multimodal Sentiment Analysis (MSA) is critical for human-computer interaction but faces challenges when the modalities are incomplete or missing. Existing methods often assume pre-defined missing modalities or fixed missing rates, limiting…

Human-Computer Interaction · Computer Science 2025-11-24 Liling Li , Guoyang Xu , Xiongri Shen , Zhifei Xu , Yanbo Zhang , Zhiguo Zhang , Zhenxi Song