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Local representation learning has been a key challenge to promote the performance of the histopathological whole slide images analysis. The previous representation learning methods followed the supervised learning paradigm. However, manual…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Jun Li , Yushan Zheng , Kun Wu , Jun Shi , Fengying Xie , Zhiguo Jiang

Accurate analysis of histopathological images is critical for disease diagnosis and treatment planning. Whole-slide images (WSIs), which digitize tissue specimens at gigapixel resolution, are fundamental to this process but require…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Enhui Chai , Sicheng Chen , Tianyi Zhang , Chad Wong , Kecheng Huang , Zeyu Liu , Fei Xia

Existing self-supervised learning methods learn representation by means of pretext tasks which are either (1) discriminating that explicitly specify which features should be separated or (2) aligning that precisely indicate which features…

Computer Vision and Pattern Recognition · Computer Science 2021-08-20 Anjan Dutta , Massimiliano Mancini , Zeynep Akata

Weakly supervised whole slide image (WSI) classification is challenging due to the lack of patch-level labels and high computational costs. State-of-the-art methods use self-supervised patch-wise feature representations for multiple…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Wentao Huang , Xiaoling Hu , Shahira Abousamra , Prateek Prasanna , Chao Chen

Multiple Instance Learning (MIL) has emerged as the best solution for Whole Slide Image (WSI) classification. It consists of dividing each slide into patches, which are treated as a bag of instances labeled with a global label. MIL includes…

Computer Vision and Pattern Recognition · Computer Science 2025-05-05 Ali Mammadov , Loic Le Folgoc , Julien Adam , Anne Buronfosse , Gilles Hayem , Guillaume Hocquet , Pietro Gori

The fine-grained annotations in whole slide images (WSIs) show the boundaries of various pathological regions. However, generating such detailed annotation is often costly, whereas the coarse annotations are relatively simpler to produce.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Bingjian Yao , Weiping Lin , Yan He , Zheng Wang , Liangsheng Wang

Unsupervised learning methods based on contrastive learning have drawn increasing attention and achieved promising results. Most of them aim to learn representations invariant to instance-level variations, which are provided by different…

Computer Vision and Pattern Recognition · Computer Science 2020-11-04 Feng Wang , Huaping Liu , Di Guo , Fuchun Sun

Whole Slide Images (WSIs) exhibit hierarchical structure, where diagnostic information emerges from cellular morphology, regional tissue organization, and global context. Existing Computational Pathology (CPath) Multimodal Large Language…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Basit Alawode , Arif Mahmood , Muaz Khalifa Al-Radi , Shahad Albastaki , Asim Khan , Muhammad Bilal , Moshira Ali Abdalla , Mohammed Bennamoun , Sajid Javed

As data requirements continue to grow, efficient learning increasingly depends on the curation and distillation of high-value data rather than brute-force scaling of model sizes. In the case of a hyperspectral image (HSI), the challenge is…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Abhiroop Chatterjee , Susmita Ghosh

Recently, contrastive learning has been shown to be effective in improving pre-trained language models (PLM) to derive high-quality sentence representations. It aims to pull close positive examples to enhance the alignment while push apart…

Computation and Language · Computer Science 2022-05-03 Kun Zhou , Beichen Zhang , Wayne Xin Zhao , Ji-Rong Wen

Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

In pre-clinical pathology, there is a paradox between the abundance of raw data (whole slide images from many organs of many individual animals) and the lack of pixel-level slide annotations done by pathologists. Due to time constraints and…

Computer Vision and Pattern Recognition · Computer Science 2023-02-06 Marco Bertolini , Van-Khoa Le , Jake Pencharz , Andreas Poehlmann , Djork-Arné Clevert , Santiago Villalba , Floriane Montanari

Multiple Instance Learning (MIL) has garnered widespread attention in the field of Whole Slide Image (WSI) classification as it replaces pixel-level manual annotation with diagnostic reports as labels, significantly reducing labor costs.…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Tianhang Nan , Hao Quan , Yong Ding , Xingyu Li , Kai Yang , Xiaoyu Cui

As the field of deep learning steadily transitions from the realm of academic research to practical application, the significance of self-supervised pretraining methods has become increasingly prominent. These methods, particularly in the…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Toni Albert , Bjoern Eskofier , Dario Zanca

Weak-strong consistency learning strategies are widely employed in semi-supervised medical image segmentation to train models by leveraging limited labeled data and enforcing weak-to-strong consistency. However, existing methods primarily…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Chaowei Chen , Xiang Zhang , Honglie Guo , Shunfang Wang

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Recent multimodal models such as Contrastive Language-Image Pre-training (CLIP) have shown remarkable ability to align visual and linguistic representations. However, domains where small visual differences carry large semantic significance,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Hiroshi Sasaki

Image-text retrieval requires the system to bridge the heterogenous gap between vision and language for accurate retrieval while keeping the network lightweight-enough for efficient retrieval. Existing trade-off solutions mainly study from…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Jiamin Zhuang , Jing Yu , Yang Ding , Xiangyan Qu , Yue Hu

Contrastive learning is a well-established paradigm in representation learning. The standard framework of contrastive learning minimizes the distance between "similar" instances and maximizes the distance between dissimilar ones in the…

Machine Learning · Computer Science 2025-02-06 Naghmeh Ghanooni , Barbod Pajoum , Harshit Rawal , Sophie Fellenz , Vo Nguyen Le Duy , Marius Kloft

Contrastive self-supervised learning has outperformed supervised pretraining on many downstream tasks like segmentation and object detection. However, current methods are still primarily applied to curated datasets like ImageNet. In this…

Computer Vision and Pattern Recognition · Computer Science 2021-12-15 Wouter Van Gansbeke , Simon Vandenhende , Stamatios Georgoulis , Luc Van Gool