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With the proliferation of large pre-trained language models (PLMs), fine-tuning all model parameters becomes increasingly inefficient, particularly when dealing with numerous downstream tasks that entail substantial training and storage…

Computation and Language · Computer Science 2024-01-23 Nadav Benedek , Lior Wolf

Human Activity Recognition is a foundational task in pervasive computing. While recent advances in self-supervised learning and transformer-based architectures have significantly improved HAR performance, adapting large pretrained models to…

Machine Learning · Computer Science 2025-12-23 Irina Seregina , Philippe Lalanda , German Vega

Low-rank adaptation (LoRA) is a fine-tuning technique that can be applied to conditional generative diffusion models. LoRA utilizes a small number of context examples to adapt the model to a specific domain, character, style, or concept.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Artur Kasymov , Marcin Sendera , Michał Stypułkowski , Maciej Zięba , Przemysław Spurek

Genotype imputation enables dense variant coverage for genome-wide association and risk-prediction studies, yet conventional reference-panel methods remain limited by ancestry bias and reduced rare-variant accuracy. We present Genotype…

Extracting clinically relevant information from unstructured medical narratives such as admission notes, discharge summaries, and emergency case histories remains a challenge in clinical natural language processing (NLP). Medical Entity…

Artificial Intelligence · Computer Science 2026-04-21 Nwe Ni Win , Jim Basilakis , Steven Thomas , Seyhan Yazar , Laura Pierce , Stephanie Liu , Paul M. Middleton , Nasser Ghadiri , X. Rosalind Wang

Large language models (LLMs) often lack specialized knowledge for complex bioinformatics applications. We present a reproducible pipeline for fine-tuning LLMs on specialized bioinformatics data, demonstrated through two use cases: PRSGPT,…

Computation and Language · Computer Science 2026-01-21 Muhammad Muneeb , David B. Ascher

Low-Rank Adaptation (LoRA) has emerged as one of the most widely used parameter-efficient fine-tuning (PEFT) methods for adapting large language models (LLMs) to downstream tasks. While highly effective in single-task settings, it struggles…

Computation and Language · Computer Science 2025-10-14 Bo Cheng , Xu Wang , Jinda Liu , Yi Chang , Yuan Wu

Information retrieval (IR) is essential in biomedical knowledge acquisition and clinical decision support. While recent progress has shown that language model encoders perform better semantic retrieval, training such models requires…

Information Retrieval · Computer Science 2024-01-17 Qiao Jin , Won Kim , Qingyu Chen , Donald C. Comeau , Lana Yeganova , W. John Wilbur , Zhiyong Lu

The early detection of mental health disorders from social media text is critical for enabling timely support, risk assessment, and referral to appropriate resources. This work introduces multiMentalRoBERTa, a fine-tuned RoBERTa model…

Computation and Language · Computer Science 2025-11-11 K M Sajjadul Islam , John Fields , Praveen Madiraju

Parameter-efficient finetuning (PEFT) aims to mitigate the substantial computational and memory overhead involved in adapting large-scale pretrained models to diverse downstream tasks. Among numerous PEFT strategies, Low-Rank Adaptation…

Artificial Intelligence · Computer Science 2025-10-10 Xiaoshuang Ji , Zhendong Zhao , Xiaoyan Gu , Xiaojun Chen , Xin Zhao , Zeyao Liu

Low-Rank Adaptation (LoRA) is a crucial method for efficiently fine-tuning large language models (LLMs), with its effectiveness influenced by two key factors: rank selection and weight initialization. While numerous LoRA variants have been…

Machine Learning · Computer Science 2025-10-27 Haonan He , Peng Ye , Yuchen Ren , Yuan Yuan , Luyang Zhou , Shucun Ju , Lei Chen

Fine-tuning large language models (LLMs) aims to adapt pre-trained models to specific tasks using relatively small and domain-specific datasets. Among Parameter-Efficient Fine-Tuning (PEFT) methods, Low-Rank Adaptation (LoRA) stands out by…

Computation and Language · Computer Science 2026-04-16 Yarui Cao , Kai Liu

Parameter-efficient adaptation has made LLMs practical for domain prediction, but standard LoRA still relies on a static low-rank update and does not expose the latent interactions that often drive scientific labels. We introduce iLoRA. To…

Machine Learning · Computer Science 2026-05-29 Yang Song , Yixuan Zhang , Lingfa Meng , Tongyuan Hu , Haizhou Shi , Hao Wang , Samir Bhatt , Hengguan Huang

This study proposes a large language model optimization method based on the improved LoRA fine-tuning algorithm, aiming to improve the accuracy and computational efficiency of the model in natural language processing tasks. We fine-tune the…

Computation and Language · Computer Science 2024-12-30 Jiacheng Hu , Xiaoxuan Liao , Jia Gao , Zhen Qi , Hongye Zheng , Chihang Wang

Parameter-Efficient Fine-Tuning (PEFT) methods like Low-Rank Adaptation (LoRA) optimize federated training by reducing computational and communication costs. We propose RoLoRA, a federated framework using alternating optimization to…

Machine Learning · Computer Science 2025-11-06 Shuangyi Chen , Yuanxin Guo , Yue Ju , Harik Dalal , Zhongwen Zhu , Ashish Khisti

Radiology reports are critical for clinical decision-making but often lack a standardized format, limiting both human interpretability and machine learning (ML) applications. While large language models (LLMs) have shown strong capabilities…

Computation and Language · Computer Science 2025-07-15 Johannes Moll , Louisa Fay , Asfandyar Azhar , Sophie Ostmeier , Tim Lueth , Sergios Gatidis , Curtis Langlotz , Jean-Benoit Delbrouck

Recent works on large language models (LLMs) have demonstrated the impact of prompting strategies and fine-tuning techniques on their reasoning capabilities. Yet, their effectiveness on clinical natural language inference (NLI) remains…

Computation and Language · Computer Science 2025-07-08 Mael Jullien , Marco Valentino , Leonardo Ranaldi , Andre Freitas

Low-rank adaptation (LoRA) is a popular method for fine-tuning large-scale pre-trained models in downstream tasks by learning low-rank incremental matrices. Though LoRA and its variants effectively reduce the number of trainable parameters…

Machine Learning · Computer Science 2024-03-21 Rushi Qiang , Ruiyi Zhang , Pengtao Xie

In this paper, we introduce a novel technique for content safety and prompt injection classification for Large Language Models. Our technique, Layer Enhanced Classification (LEC), trains a Penalized Logistic Regression (PLR) classifier on…

Computation and Language · Computer Science 2024-12-19 Mason Sawtell , Tula Masterman , Sandi Besen , Jim Brown

Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which reduces their usefulness in clinical settings. Prototype learning presents a potential solution,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Shuo Jiang , Zhuwen Chen , Liaoman Xu , Yanming Zhu , Changmiao Wang , Jiong Zhang , Feiwei Qin , Yifei Chen , Zhu Zhu