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Segmentation of ultra-high resolution images is increasingly demanded, yet poses significant challenges for algorithm efficiency, in particular considering the (GPU) memory limits. Current approaches either downsample an ultra-high…

Computer Vision and Pattern Recognition · Computer Science 2021-03-04 Wuyang Chen , Ziyu Jiang , Zhangyang Wang , Kexin Cui , Xiaoning Qian

Our study presents PNN-UNet as a method for constructing deep neural networks that replicate the planarian neural network (PNN) structure in the context of 3D medical image data. Planarians typically have a cerebral structure comprising two…

Image and Video Processing · Electrical Eng. & Systems 2025-05-09 Ziyuan Huang , Kevin Huggins , Srikar Bellur

Brain network analysis based on functional Magnetic Resonance Imaging (fMRI) is pivotal for diagnosing brain disorders. Existing approaches typically rely on predefined functional sub-networks to construct sub-network associations. However,…

Machine Learning · Computer Science 2026-03-11 Jingfeng Tang , Peng Cao , Guangqi Wen , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane

The human brain has been studied at multiple scales, from neurons, circuits, areas with well defined anatomical and functional boundaries, to large-scale functional networks which mediate coherent cognition. In a recent work, we addressed…

Biological Physics · Physics 2012-05-17 Lazaros K. Gallos , Mariano Sigman , Hernan A. Makse

Effective representation of brain anatomical architecture is fundamental in understanding brain regularity and variability. Despite numerous efforts, it is still difficult to infer reliable anatomical correspondence at finer scale, given…

Neurons and Cognition · Quantitative Biology 2022-05-30 Lu Zhang , Xiaowei Yu , Yanjun Lyu , Zhengwang Wu , Haixing Dai , Lin Zhao , Li Wang , Gang Li , Tianming Liu , Dajiang Zhu

We design deep neural networks (DNNs) and corresponding networks' splittings to distribute DNNs' workload to camera sensors and a centralized aggregator on head mounted devices to meet system performance targets in inference accuracy and…

Machine Learning · Computer Science 2022-04-12 Xin Dong , Barbara De Salvo , Meng Li , Chiao Liu , Zhongnan Qu , H. T. Kung , Ziyun Li

Gliomas are brain tumor types that have a high mortality rate which means early and accurate diagnosis is important for therapeutic intervention for the tumors. To address this difficulty, the proposed research will develop a hybrid deep…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Pandiyaraju V , Sreya Mynampati , Abishek Karthik , Poovarasan L , D. Saraswathi

Modular structure is ubiquitous among real-world networks from related proteins to social groups. Here we analyze the modular organization of brain networks at a large-scale (voxel level) extracted from functional magnetic resonance imaging…

Data Analysis, Statistics and Probability · Physics 2009-04-16 M. Valencia , M. A. Pastor , MA. Fernandez-Seara , J. Artieda , J. Martinerie , M. Chavez

Bone metastasis analysis is a significant challenge in pathology and plays a critical role in determining patient quality of life and treatment strategies. The microenvironment and specific tissue structures are essential for pathologists…

Computer Vision and Pattern Recognition · Computer Science 2025-01-29 Yuxuan Chen , Jiawen Li , Huijuan Shi , Yang Xu , Tian Guan , Lianghui Zhu , Yonghong He , Anjia Han

Understanding how cortex, subcortex and cerebellum integrate is a major challenge for neuroscience, however, studies of the brain's structural connectivity have mostly focused on cortico-cortical links. Here, we used diffusion imaging to…

Neurons and Cognition · Quantitative Biology 2025-10-21 Julian Schulte , Mario Senden , Gustavo Deco , Xenia Kobeleva , Gorka Zamora-López

One of the critical steps in improving accurate single neuron reconstruction from three-dimensional (3D) optical microscope images is the neuronal structure segmentation. However, they are always hard to segment due to the lack in quality.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-25 Heng Wang , Yang Song , Chaoyi Zhang , Jianhui Yu , Siqi Liu , Hanchuan Peng , Weidong Cai

The human brain can be considered as complex networks, composed of various regions that continuously exchange their information with each other, forming the brain network graph, from which nodes and edges are extracted using resting-state…

Machine Learning · Computer Science 2025-02-19 Parnian Jalali , Mehran Safayani

Expressivity plays a fundamental role in evaluating deep neural networks, and it is closely related to understanding the limit of performance improvement. In this paper, we propose a three-pipeline training framework based on critical…

Machine Learning · Computer Science 2020-12-17 Gege Zhang

Graph Transformer shows remarkable potential in brain network analysis due to its ability to model graph structures and complex node relationships. Most existing methods typically model the brain as a flat network, ignoring its modular…

Machine Learning · Computer Science 2025-11-25 Jiajun Ma , Yongchao Zhang , Chao Zhang , Zhao Lv , Shengbing Pei

This paper represents a contribution to the study of the brain functional connectivity from the perspective of complex networks theory. More specifically, we apply graph theoretical analyses to provide evidence of the modular structure of…

Neurons and Cognition · Quantitative Biology 2016-09-06 Giampiero Bardella , Angelo Bifone , Andrea Gabrielli , Alessandro Gozzi , Tiziano Squartini

The analysis of glandular morphology within colon histopathology images is an important step in determining the grade of colon cancer. Despite the importance of this task, manual segmentation is laborious, time-consuming and can suffer from…

Computer Vision and Pattern Recognition · Computer Science 2019-02-19 Simon Graham , Hao Chen , Jevgenij Gamper , Qi Dou , Pheng-Ann Heng , David Snead , Yee Wah Tsang , Nasir Rajpoot

Cytoarchitecture describes the spatial organization of neuronal cells in the brain, including their arrangement into layers and columns with respect to cell density, orientation, or presence of certain cell types. It allows to segregate the…

Image and Video Processing · Electrical Eng. & Systems 2022-01-02 Christian Schiffer , Stefan Harmeling , Katrin Amunts , Timo Dickscheid

With the frequent happening of privacy leakage and the enactment of privacy laws across different countries, data owners are reluctant to directly share their raw data and labels with any other party. In reality, a lot of these raw data are…

Machine Learning · Computer Science 2023-01-31 Xiaolong Xu , Lingjuan Lyu , Yihong Dong , Yicheng Lu , Weiqiang Wang , Hong Jin

Can complex engineered and biological networks be coarse-grained into smaller and more understandable versions in which each node represents an entire pattern in the original network? To address this, we define coarse-graining units (CGU)…

Molecular Networks · Quantitative Biology 2009-11-10 Shalev Itzkovitz , Reuven Levitt , Nadav Kashtan , Ron Milo , Michael Itzkovitz , Uri Alon

Accurate segmentation of organs at risk in the head and neck is essential for radiation therapy, yet deep learning models often fail on small, complexly shaped organs. While hybrid architectures that combine different models show promise,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Xiaoyu Liu , Siwen Wei , Linhao Qu , Mingyuan Pan , Chengsheng Zhang , Yonghong Shi , Zhijian Song