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We present CardiacGen, a Deep Learning framework for generating synthetic but physiologically plausible cardiac signals like ECG. Based on the physiology of cardiovascular system function, we propose a modular hierarchical generative model…

Machine Learning · Computer Science 2022-11-16 Tushar Agarwal , Emre Ertin

Image generation remains a fundamental problem in artificial intelligence in general and deep learning in specific. The generative adversarial network (GAN) was successful in generating high quality samples of natural images. We propose a…

Artificial Intelligence · Computer Science 2016-11-15 Hanock Kwak , Byoung-Tak Zhang

We propose generative neural network methods to generate DNA sequences and tune them to have desired properties. We present three approaches: creating synthetic DNA sequences using a generative adversarial network; a DNA-based variant of…

Machine Learning · Computer Science 2017-12-19 Nathan Killoran , Leo J. Lee , Andrew Delong , David Duvenaud , Brendan J. Frey

Analyzing medical data to find abnormalities is a time-consuming and costly task, particularly for rare abnormalities, requiring tremendous efforts from medical experts. Artificial intelligence has become a popular tool for the automatic…

Age progression and regression aim to synthesize photorealistic appearance of a given face image with aging and rejuvenation effects, respectively. Existing generative adversarial networks (GANs) based methods suffer from the following…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Zhizhong Huang , Shouzhen Chen , Junping Zhang , Hongming Shan

Scene graphs provide a rich, structured representation of a scene by encoding the entities (objects) and their spatial relationships in a graphical format. This representation has proven useful in several tasks, such as question answering,…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Sanjoy Kundu , Sathyanarayanan N. Aakur

Antibody therapies have been employed to address some of today's most challenging diseases, but must meet many criteria during drug development before reaching a patient. Humanization is a sequence optimization strategy that addresses one…

Machine Learning · Computer Science 2024-12-10 Cade Gordon , Aniruddh Raghu , Peyton Greenside , Hunter Elliott

As a new approach to train generative models, \emph{generative adversarial networks} (GANs) have achieved considerable success in image generation. This framework has also recently been applied to data with graph structures. We propose…

Machine Learning · Computer Science 2021-02-26 Shuangfei Fan , Bert Huang

Designing RNA molecules that interact with specific proteins is a critical challenge in experimental and computational biology. Existing computational approaches require a substantial amount of previously known interacting RNA sequences for…

Machine Learning · Computer Science 2026-04-17 Roman Klypa , Alberto Bietti , Sergei Grudinin

Deterministic complex networks that use iterative generation algorithms have been found to more closely mirror properties found in real world networks than the traditional uniform random graph models. In this paper we introduce a new,…

Combinatorics · Mathematics 2022-09-05 Erin Meger , Abigail Raz

The visual world we sense, interpret and interact everyday is a complex composition of interleaved physical entities. Therefore, it is a very challenging task to generate vivid scenes of similar complexity using computers. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2019-02-05 Mehmet Ozgur Turkoglu , William Thong , Luuk Spreeuwers , Berkay Kicanaoglu

Graph data structures are fundamental for studying connected entities. With an increase in the number of applications where data is represented as graphs, the problem of graph generation has recently become a hot topic. However, despite its…

Many real-world user queries (e.g. "How do to make egg fried rice?") could benefit from systems capable of generating responses with both textual steps with accompanying images, similar to a cookbook. Models designed to generate interleaved…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Dongping Chen , Ruoxi Chen , Shu Pu , Zhaoyi Liu , Yanru Wu , Caixi Chen , Benlin Liu , Yue Huang , Yao Wan , Pan Zhou , Ranjay Krishna

Discovering genes with similar functions across diverse biomedical contexts poses a significant challenge in gene representation learning due to data heterogeneity. In this study, we resolve this problem by introducing a novel model called…

Machine Learning · Computer Science 2023-10-05 Tianyu Liu , Yuge Wang , Rex Ying , Hongyu Zhao

Drug discovery is a complex, resource-intensive process requiring significant time and cost to bring new medicines to patients. Many generative models aim to accelerate drug discovery, but few produce synthetically accessible molecules.…

Machine Learning · Computer Science 2025-01-30 Zygimantas Jocys , Zhanxing Zhu , Henriette M. G. Willems , Katayoun Farrahi

In recent years, deep learning has been successfully adopted in a wide range of applications related to electronic health records (EHRs) such as representation learning and clinical event prediction. However, due to privacy constraints,…

Machine Learning · Computer Science 2023-09-04 Chang Lu , Chandan K. Reddy , Ping Wang , Dong Nie , Yue Ning

Deep learning has made significant progress in protein structure prediction, advancing the development of computational biology. However, despite the high accuracy achieved in predicting single-chain structures, a significant number of…

Biomolecules · Quantitative Biology 2024-03-08 Zhaoqun Li , Jingcheng Yu , Qiwei Ye

Personalized mathematics education is growing rapidly, creating a strong demand for large sets of similar practice problems. Yet existing studies on mathematics problem generation have focused on data augmentation for training neural…

Artificial Intelligence · Computer Science 2025-11-12 Jeong-Hoon Kim , Jinwoo Nam , Geunsik Jo

Creating new documents by synthesizing information from existing sources is an important part of knowledge work in many domains. This process often involves gathering content from multiple documents, organizing it, and then transforming it…

Human-Computer Interaction · Computer Science 2026-03-02 Balasaravanan Thoravi Kumaravel

AI-Generated Content (AIGC) has recently gained a surge in popularity, powered by its high efficiency and consistency in production, and its capability of being customized and diversified. The cross-modality nature of the representation…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Zuhao Yang , Huajun Bai , Zhang Luo , Yang Xu , Wei Pang , Yue Wang , Yisheng Yuan , Yingfang Yuan