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Background: The most widely used approach to joint modelling of repeated measurement and time to event data is to combine a linear Gaussian random effects model for the repeated measurements with a log-Gaussian frailty model for the…

Methodology · Statistics 2016-09-12 Elisabeth Waldmann , David Taylor-Robinson

Imaging flow cytometry shows significant potential for increasing our understanding of heterogeneous and complex life systems and is useful for biomedical applications. Ghost cytometry is a recently proposed approach for directly analyzing…

Purpose: Digital phantoms are one of the key components of virtual imaging trials (VITs) that aim to assess and optimize new medical imaging systems and algorithms. However, these phantoms vary in their voxel resolution, appearance, and…

Medical Physics · Physics 2024-02-02 Amar Kavuri , Mini Das

Early and accurate diagnosis of interstitial lung diseases (ILDs) is crucial for making treatment decisions, but can be challenging even for experienced radiologists. The diagnostic procedure is based on the detection and recognition of the…

Computer Vision and Pattern Recognition · Computer Science 2018-04-02 Marios Anthimopoulos , Stergios Christodoulidis , Lukas Ebner , Thomas Geiser , Andreas Christe , Stavroula Mougiakakou

Statistical models for predicting lung cancer have the potential to facilitate earlier diagnosis of malignancy and avoid invasive workup of benign disease. Many models have been published, but comparative studies of their utility in…

Recently, Computer-Aided Diagnosis (CAD) systems have emerged as indispensable tools in clinical diagnostic workflows, significantly alleviating the burden on radiologists. Nevertheless, despite their integration into clinical settings, CAD…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Muwei Jian , Hongyu Chen , Zaiyong Zhang , Nan Yang , Haorang Zhang , Lifu Ma , Wenjing Xu , Huixiang Zhi

Segmentation of the bronchovascular bundle within the lung parenchyma is a key step for the proper analysis and planning of many pulmonary diseases. It might also be considered the preprocessing step when the goal is to segment the nodules…

While the acute phase of the COVID-19 pandemic has subsided, its long-term effects persist through Post-Acute Sequelae of COVID-19 (PASC), commonly known as Long COVID. There remains substantial uncertainty regarding both its duration and…

Objectives: The main objective of this review article is to evaluate the usability of Computational Fluid Dynamics (CFD) as a supporting clinical tool for respiratory system. Data Source: The English articles referred for this review paper…

Fluid Dynamics · Physics 2023-10-24 Rajneesh Kashyap , R. Thundil Karuppa Raj

Purpose: to optimize a pipeline of clinical data gathering and CT images processing implemented during the COVID-19 pandemic crisis and to develop artificial intelligence model for different of viral pneumonia. Methods: 1028 chest CT image…

Medical Physics · Physics 2021-09-30 Giulia Zorzi , Luca Berta , Stefano Carrazza , Alberto Torresin

Total lung volume is an important quantitative biomarker and is used for the assessment of restrictive lung diseases. In this study, we investigate the performance of several deep-learning approaches for automated measurement of total lung…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Ecem Sogancioglu , Keelin Murphy , Ernst Th. Scholten , Luuk H. Boulogne , Mathias Prokop , Bram van Ginneken

This paper proposes a novel and efficient method to build a Computer-Aided Diagnoses (CAD) system for lung nodule detection based on Computed Tomography (CT). This task was treated as an Object Detection on Video (VID) problem by imitating…

Computer Vision and Pattern Recognition · Computer Science 2017-12-15 Ning Li , Haopeng Liu , Bin Qiu , Wei Guo , Shijun Zhao , Kungang Li , Jie He

Lung cancer, a malignancy originating in lung tissues, is commonly diagnosed and classified using medical imaging techniques, particularly computed tomography (CT). Despite the integration of machine learning and deep learning methods, the…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Olajumoke O. Adekunle , Joseph D. Akinyemi , Khadijat T. Ladoja , Olufade F. W. Onifade

Accurately and precisely characterizing the morphology of small pulmonary structures from Computed Tomography (CT) images, such as airways and vessels, is becoming of great importance for diagnosis of pulmonary diseases. The smaller…

Image and Video Processing · Electrical Eng. & Systems 2020-04-13 Pietro Nardelli , James C. Ross , Raúl San José Estépar

Purpose: Functional imaging is emerging as an important tool for lung cancer treatment planning and evaluation. Compared with traditional methods such as nuclear medicine ventilation-perfusion (VQ), positron emission tomography (PET),…

Purpose: 4D CBCT is a beneficial tool for the treatment of movable tumors, because it can help us to understand where the tumors are actually located and have a precise treatment plan. However, there is a limitation that general CBCT images…

In the management of lung nodules, we are desirable to predict nodule evolution in terms of its diameter variation on Computed Tomography (CT) scans and then provide a follow-up recommendation according to the predicted result of the…

Image and Video Processing · Electrical Eng. & Systems 2022-06-08 Jiansheng Fang , Jingwen Wang , Anwei Li , Yuguang Yan , Yonghe Hou , Chao Song , Hongbo Liu , Jiang Liu

We explore a solution for learning disease signatures from weakly, yet easily obtainable, annotated volumetric medical imaging data by analyzing 3D volumes as a sequence of 2D images. We demonstrate the performance of our solution in the…

Computer Vision and Pattern Recognition · Computer Science 2020-01-27 Nathaniel Braman , David Beymer , Ehsan Dehghan

Abstract Background: Pulmonary function tests (PFTs) and computed tomography (CT) imaging are vital in diagnosing, managing, and monitoring lung diseases. A common issue in practice is the lack of access to recorded pulmonary functions…

Image and Video Processing · Electrical Eng. & Systems 2024-08-13 Kaiwen Geng , Zhiyi Shi , Xiaoyan Zhao , Alaa Ali , Jing Wang , Joseph Leader , Jiantao Pu

Large language models (LLMs) increasingly reach real-world applications, necessitating a better understanding of their behaviour. Their size and complexity complicate traditional assessment methods, causing the emergence of alternative…

Artificial Intelligence · Computer Science 2025-05-13 Sanne Peereboom , Inga Schwabe , Bennett Kleinberg
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