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Recent advancements in diffusion models have showcased their impressive capacity to generate visually striking images. Nevertheless, ensuring a close match between the generated image and the given prompt remains a persistent challenge. In…

Computer Vision and Pattern Recognition · Computer Science 2023-09-11 Yupeng Zhou , Daquan Zhou , Zuo-Liang Zhu , Yaxing Wang , Qibin Hou , Jiashi Feng

Acquiring and annotating sufficient labeled data is crucial in developing accurate and robust learning-based models, but obtaining such data can be challenging in many medical image segmentation tasks. One promising solution is to…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Kun Han , Yifeng Xiong , Chenyu You , Pooya Khosravi , Shanlin Sun , Xiangyi Yan , James Duncan , Xiaohui Xie

Diffusion models have shown remarkable success across a wide range of generative tasks. However, they often suffer from spatially inconsistent generation, arguably due to the inherent locality of their denoising mechanisms. This can yield…

Machine Learning · Computer Science 2026-02-04 Wenshuai Zhao , Zhiyuan Li , Yi Zhao , Mohammad Hassan Vali , Martin Trapp , Joni Pajarinen , Juho Kannala , Arno Solin

Image denoising is a fundamental problem in computational photography, where achieving high perception with low distortion is highly demanding. Current methods either struggle with perceptual quality or suffer from significant distortion.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Tong Li , Hansen Feng , Lizhi Wang , Zhiwei Xiong , Hua Huang

Semi-implicit distributions have shown great promise in variational inference and generative modeling. Hierarchical semi-implicit models, which stack multiple semi-implicit layers, enhance the expressiveness of semi-implicit distributions…

Machine Learning · Statistics 2025-06-10 Longlin Yu , Jiajun Zha , Tong Yang , Tianyu Xie , Xiangyu Zhang , S. -H. Gary Chan , Cheng Zhang

Scarcity of annotated data, particularly for rare or atypical morphologies, present significant challenges for cell and nuclei segmentation in computational pathology. While manual annotation is labor-intensive and costly, synthetic data…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Dominik Winter , Mai Bui , Monica Azqueta Gavaldon , Nicolas Triltsch , Marco Rosati , Nicolas Brieu

Although masked image generation models and masked diffusion models are designed with different motivations and objectives, we observe that they can be unified within a single framework. Building upon this insight, we carefully explore the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Zebin You , Jingyang Ou , Xiaolu Zhang , Jun Hu , Jun Zhou , Chongxuan Li

Current deep networks are very data-hungry and benefit from training on largescale datasets, which are often time-consuming to collect and annotate. By contrast, synthetic data can be generated infinitely using generative models such as…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Weijia Wu , Yuzhong Zhao , Hao Chen , Yuchao Gu , Rui Zhao , Yefei He , Hong Zhou , Mike Zheng Shou , Chunhua Shen

Recent advances in Diffusion Probabilistic Models (DPMs) have set new standards in high-quality image synthesis. Yet, controlled generation remains challenging, particularly in sensitive areas such as medical imaging. Medical images feature…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Sarah Cechnicka , Matthew Baugh , Weitong Zhang , Mischa Dombrowski , Zhe Li , Johannes C. Paetzold , Candice Roufosse , Bernhard Kainz

Simulating in silico cellular responses to interventions is a promising direction to accelerate high-content image-based assays, critical for advancing drug discovery and gene editing. To support this, we introduce MorphGen, a…

Quantitative Methods · Quantitative Biology 2025-10-13 Berker Demirel , Marco Fumero , Theofanis Karaletsos , Francesco Locatello

Recent advances in denoising diffusion probabilistic models have shown great success in image synthesis tasks. While there are already works exploring the potential of this powerful tool in image semantic segmentation, its application in…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Xinrong Hu , Yu-Jen Chen , Tsung-Yi Ho , Yiyu Shi

The bifurcation of generative modeling into autoregressive approaches for discrete data (text) and diffusion approaches for continuous data (images) hinders the development of truly unified multimodal systems. While Masked Language Models…

Computation and Language · Computer Science 2026-01-08 Yuanfeng Xu , Yuhao Chen , Liang Lin , Guangrun Wang

Recent advancements in deep learning for medical image segmentation are often limited by the scarcity of high-quality training data.While diffusion models provide a potential solution by generating synthetic images, their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Jianhao Xie , Ziang Zhang , Zhenyu Weng , Yuesheng Zhu , Guibo Luo

Medical image analysis plays a pivotal role in the early diagnosis of diseases such as skin lesions. However, the scarcity of data and the class imbalance significantly hinder the performance of deep learning models. We propose a novel…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Zhaobin Xu

Text-conditioned molecular generation aims to translate natural-language descriptions into chemical structures, enabling scientists to specify functional groups, scaffolds, and physicochemical constraints without handcrafted rules.…

Machine Learning · Computer Science 2025-11-18 Lingxiao Li , Haobo Zhang , Bin Chen , Jiayu Zhou

Semantic segmentation is a computer vision task where classification is performed at a pixel level. Due to this, the process of labeling images for semantic segmentation is time-consuming and expensive. To mitigate this cost there has been…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Javier Montalvo , Álvaro García-Martín , Pablo Carballeira , Juan C. SanMiguel

Text-to-image synthesis has achieved high-quality results with recent advances in diffusion models. However, text input alone has high spatial ambiguity and limited user controllability. Most existing methods allow spatial control through…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Yuki Endo

Continuous Conditional Generative Modeling (CCGM) estimates high-dimensional data distributions, such as images, conditioned on scalar continuous variables (aka regression labels). While Continuous Conditional Generative Adversarial…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Xin Ding , Yongwei Wang , Kao Zhang , Z. Jane Wang

Diffusion models have fundamentally transformed the field of generative models, making the assessment of similarity between customized model outputs and reference inputs critically important. However, traditional perceptual similarity…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Yiren Song , Xiaokang Liu , Mike Zheng Shou

In this study we develop dimension-reduction techniques to accelerate diffusion model inference in the context of synthetic data generation. The idea is to integrate compressed sensing into diffusion models (hence, CSDM): First, compress…

Machine Learning · Statistics 2025-09-30 Zhengyi Guo , Jiatu Li , Wenpin Tang , David D. Yao