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The field of medical diagnostics contains a wealth of challenges which closely resemble classical machine learning problems; practical constraints, however, complicate the translation of these endpoints naively into classical architectures.…

Computer Vision and Pattern Recognition · Computer Science 2018-02-05 Li Yao , Eric Poblenz , Dmitry Dagunts , Ben Covington , Devon Bernard , Kevin Lyman

Causal reasoning is a cornerstone of human intelligence and a critical capability for artificial systems aiming to achieve advanced understanding and decision-making. This thesis delves into various dimensions of causal reasoning and…

Computation and Language · Computer Science 2025-04-22 Zhijing Jin

Aligning the decision-making process of machine learning algorithms with that of experienced radiologists is crucial for reliable diagnosis. While existing methods have attempted to align their diagnosis behaviors to those of radiologists…

Machine Learning · Computer Science 2025-02-10 Mingzhou Liu , Ching-Wen Lee , Xinwei Sun , Yu Qiao , Yizhou Wang

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models…

Machine Learning · Computer Science 2023-11-21 Alice Bernasconi , Alessio Zanga , Peter J. F. Lucas , Marco Scutari , Fabio Stella

Causal decision making (CDM) based on machine learning has become a routine part of business. Businesses algorithmically target offers, incentives, and recommendations to affect consumer behavior. Recently, we have seen an acceleration of…

Machine Learning · Statistics 2021-10-01 Carlos Fernández-Loría , Foster Provost

In most nonrandomized observational studies, differences between treatment groups may arise not only due to the treatment but also because of the effect of confounders. Therefore, causal inference regarding the treatment effect is not as…

Methodology · Statistics 2018-07-04 Debashis Ghosh

Current clinical decision support systems (CDSSs) typically base their predictions on correlation, not causation. In recent years, causal machine learning (ML) has emerged as a promising way to improve decision-making with CDSSs by offering…

Human-Computer Interaction · Computer Science 2026-04-17 Domenique Zipperling , Lukas Schmidt , Benedikt Hahn , Niklas Kühl , Steven Kimbrough

Causal learning is the cognitive process of developing the capability of making causal inferences based on available information, often guided by normative principles. This process is prone to errors and biases, such as the illusion of…

Deep learning (DL) has recently drawn much attention in image analysis, natural language process, and high-dimensional medical data analysis. Under the causal direct acyclic graph (DAG) interpretation, the input variables without incoming…

Applications · Statistics 2022-03-22 Jong-Hyeon Jeong , Yichen Jia

Many benchmarks for automated causal inference evaluate a system's performance based on a single numerical output, such as an Average Treatment Effect (ATE). This approach conflates two distinct steps in causal analysis: identification -…

Artificial Intelligence · Computer Science 2026-05-15 Ayush Sawarni , Jiyuan Tan , Vasilis Syrgkanis

Prior behavioural work suggests that some LLMs alter choices when options are framed as causing pain or pleasure, and that such deviations can scale with stated intensity. To bridge behavioural evidence (what the model does) with…

Artificial Intelligence · Computer Science 2026-02-24 Francesca Bianco , Derek Shiller

Background: Symbolic models, particularly decision trees, are widely used in software engineering for explainable analytics in defect prediction, configuration tuning, and software quality assessment. Most of these models rely on…

Software Engineering · Computer Science 2026-02-19 Amirali Rayegan , Tim Menzies

Prediction and causal explanation are fundamentally distinct tasks of data analysis. In health applications, this difference can be understood in terms of the difference between prognosis (prediction) and prevention/treatment (causal…

Consider the problem of estimating the causal effect of some attribute of a text document; for example: what effect does writing a polite vs. rude email have on response time? To estimate a causal effect from observational data, we need to…

Machine Learning · Statistics 2023-02-09 Lin Gui , Victor Veitch

Causal learning is the cognitive process of developing the capability of making causal inferences based on available information, often guided by normative principles. This process is prone to errors and biases, such as the illusion of…

While witnessing the exceptional success of machine learning (ML) technologies in many applications, users are starting to notice a critical shortcoming of ML: correlation is a poor substitute for causation. The conventional way to discover…

Machine Learning · Computer Science 2024-09-26 Ahmet Kapkiç , Pratanu Mandal , Shu Wan , Paras Sheth , Abhinav Gorantla , Yoonhyuk Choi , Huan Liu , K. Selçuk Candan

The causal capabilities of large language models (LLMs) are a matter of significant debate, with critical implications for the use of LLMs in societally impactful domains such as medicine, science, law, and policy. We conduct a "behavorial"…

Artificial Intelligence · Computer Science 2024-08-21 Emre Kıcıman , Robert Ness , Amit Sharma , Chenhao Tan

Probabilistic machine learning models are often insufficient to help with decisions on interventions because those models find correlations - not causal relationships. If observational data is only available and experimentation are…

Artificial Intelligence · Computer Science 2021-05-13 Marios Papamichalis , Abhishek Ray , Ilias Bilionis , Karthik Kannan , Rajiv Krishnamurthy

Treatment effect estimation involves assessing the impact of different treatments on individual outcomes. Current methods estimate Conditional Average Treatment Effect (CATE) using observational datasets where covariates are collected…

Machine Learning · Computer Science 2025-02-10 Lokesh Nagalapatti , Pranava Singhal , Avishek Ghosh , Sunita Sarawagi

The importance of clinical variables in the prognosis of the disease is explained using statistical correlation or machine learning (ML). However, the predictive importance of these variables may not represent their causal relationships…

Machine Learning · Statistics 2025-06-04 Yina Hou , Shourav B. Rabbani , Liang Hong , Norou Diawara , Manar D. Samad