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The reliable segmentation of retinal vasculature can provide the means to diagnose and monitor the progression of a variety of diseases affecting the blood vessel network, including diabetes and hypertension. We leverage the power of…

Image and Video Processing · Electrical Eng. & Systems 2019-07-23 Ali Hatamizadeh , Hamid Hosseini , Zhengyuan Liu , Steven D. Schwartz , Demetri Terzopoulos

Diabetic retinopathy (DR) is a complication of diabetes that severely affects eyes. It can be graded into five levels of severity according to international protocol. However, optimizing a grading model to have strong generalizability…

Image and Video Processing · Electrical Eng. & Systems 2020-12-22 Yi Zhou , Boyang Wang , Xiaodong He , Shanshan Cui , Ling Shao

Convolutional neural networks (CNNs) show impressive performance for image classification and detection, extending heavily to the medical image domain. Nevertheless, medical experts are sceptical in these predictions as the nonlinear…

Computer Vision and Pattern Recognition · Computer Science 2017-06-30 Waleed M. Gondal , Jan M. Köhler , René Grzeszick , Gernot A. Fink , Michael Hirsch

Diabetic Retinopathy (DR) is a leading cause of vision loss in the world,. In the past few Diabetic Retinopathy (DR) is a leading cause of vision loss in the world. In the past few years, Artificial Intelligence (AI) based approaches have…

Image and Video Processing · Electrical Eng. & Systems 2021-07-02 Vasudevan Lakshminarayanan , Hoda Kherdfallah , Arya Sarkar , J. Jothi Balaji

Microaneurysms (MAs), the earliest pathognomonic signs of Diabetic Retinopathy (DR), present as sub-60 $\mu m$ lesions in fundus images with highly variable photometric and morphological characteristics, rendering manual screening not only…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Yifei Sun , Yuzhi He , Junhao Jia , Jinhong Wang , Ruiquan Ge , Changmiao Wang , Hongxia Xu

Optical coherence tomography (OCT) is used for non-invasive diagnosis of diabetic macular edema assessing the retinal layers. In this paper, we propose a new fully convolutional deep architecture, termed ReLayNet, for end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2017-07-10 Abhijit Guha Roy , Sailesh Conjeti , Sri Phani Krishna Karri , Debdoot Sheet , Amin Katouzian , Christian Wachinger , Nassir Navab

In this report, we applied integrated gradients to explaining a neural network for diabetic retinopathy detection. The integrated gradient is an attribution method which measures the contributions of input to the quantity of interest. We…

Artificial Intelligence · Computer Science 2017-10-19 Linyi Li , Matt Fredrikson , Shayak Sen , Anupam Datta

The application of Artificial Intelligence in the medical market brings up increasing concerns but aids in more timely diagnosis of silent progressing diseases like Diabetic Retinopathy. In order to diagnose Diabetic Retinopathy (DR),…

Image and Video Processing · Electrical Eng. & Systems 2023-10-18 Sharan Subramanian , Leilani H. Gilpin

Retinal diseases such as Diabetic Retinopathy (DR) and Macular Hole (MH) significantly impact vision and affect millions worldwide. Early detection is crucial, as DR, a complication of diabetes, damages retinal blood vessels, potentially…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Duaa Kareem Qasim , Sabah Abdulazeez Jebur , Lafta Raheem Ali , Abdul Jalil M. Khalaf , Abir Jaafar Hussain

Accurate retinal vessel segmentation is an important task for many computer-aided diagnosis systems. Yet, it is still a challenging problem due to the complex vessel structures of an eye. Numerous vessel segmentation methods have been…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Ali Karaali , Rozenn Dahyot , Donal J. Sexton

Diabetic retinopathy is a leading cause of blindness in diabetic patients and early detection plays a crucial role in preventing vision loss. Traditional diagnostic methods are often time-consuming and prone to errors. The emergence of deep…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Saif Ur Rehman Khan , Muhammad Nabeel Asim , Sebastian Vollmer , Andreas Dengel

WHO has declared that more than 2.2 billion people worldwide are suffering from visual disorders, such as media haze, glaucoma, and drusen. At least 1 billion of these cases could have been either prevented or successfully treated, yet they…

Image and Video Processing · Electrical Eng. & Systems 2024-05-30 Yavuz Selim Inan

Timely and affordable computer-aided diagnosis of retinal diseases is pivotal in precluding blindness. Accurate retinal vessel segmentation plays an important role in disease progression and diagnosis of such vision-threatening diseases. To…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Tariq M. Khan , Syed S. Naqvi , Antonio Robles-Kelly , Imran Razzak

Diabetic Retinopathy (DR), a prevalent and severe complication of diabetes, affects millions of individuals globally, underscoring the need for accurate and timely diagnosis. Recent advancements in imaging technologies, such as…

Diabetic retinopathy (DR) and diabetic macular edema (DME) are the leading causes of permanent blindness in the working-age population. Automatic grading of DR and DME helps ophthalmologists design tailored treatments to patients, thus is…

Image and Video Processing · Electrical Eng. & Systems 2019-11-05 Xiaomeng Li , Xiaowei Hu , Lequan Yu , Lei Zhu , Chi-Wing Fu , Pheng-Ann Heng

Diabetic Retinopathy (DR) is considered one of the significant concerns worldwide, primarily due to its impact on causing vision loss among most people with diabetes. The severity of DR is typically comprehended manually by ophthalmologists…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Tejas Karkera , Chandranath Adak , Soumi Chattopadhyay , Muhammad Saqib

Super-resolution (SR) aims to enhance the quality of low-resolution images and has been widely applied in medical imaging. We found that the design principles of most existing methods are influenced by SR tasks based on real-world images…

Image and Video Processing · Electrical Eng. & Systems 2025-11-14 Feiyang Jia , Zhineng Chen , Ziying Song , Lin Liu , Caiyan Jia

Longitudinal imaging is able to capture both static anatomical structures and dynamic changes in disease progression toward earlier and better patient-specific pathology management. However, conventional approaches rarely take advantage of…

The diagnosis of medical diseases faces challenges such as the misdiagnosis of small lesions. Deep learning, particularly multimodal approaches, has shown great potential in the field of medical disease diagnosis. However, the differences…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Jianxun Yu , Ruiquan Ge , Zhipeng Wang , Cheng Yang , Chenyu Lin , Xianjun Fu , Jikui Liu , Ahmed Elazab , Changmiao Wang

Skin cancer is a highly dangerous type of cancer that requires an accurate diagnosis from experienced physicians. To help physicians diagnose skin cancer more efficiently, a computer-aided diagnosis (CAD) system can be very helpful. In this…

Image and Video Processing · Electrical Eng. & Systems 2024-06-24 Ayush Roy , Sujan Sarkar , Sohom Ghosal , Dmitrii Kaplun , Asya Lyanova , Ram Sarkar