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Multimodal deep learning has been used to predict clinical endpoints and diagnoses from clinical routine data. However, these models suffer from scaling issues: they have to learn pairwise interactions between each piece of information in…

Multi-organ segmentation holds paramount significance in many clinical tasks. In practice, compared to large fully annotated datasets, multiple small datasets are often more accessible and organs are not labelled consistently. Normally, an…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Zhendi Gong , Susan Francis , Eleanor Cox , Stamatios N. Sotiropoulos , Dorothee P. Auer , Guoping Qiu , Andrew P. French , Xin Chen

The integration of DNA methylation data with a Whole Slide Image (WSI) offers significant potential for enhancing the diagnostic precision of central nervous system (CNS) tumor classification in neuropathology. While existing approaches…

Computer Vision and Pattern Recognition · Computer Science 2024-12-12 Omnia Alwazzan , Amaya Gallagher-Syed , Thomas O. Millner , Sebastian Brandner , Ioannis Patras , Silvia Marino , Gregory Slabaugh

Detecting predictive biomarkers from multi-omics data is important for precision medicine, to improve diagnostics of complex diseases and for better treatments. This needs substantial experimental efforts that are made difficult by the…

Quantitative Methods · Quantitative Biology 2021-06-08 Betül Güvenç Paltun , Samuel Kaski , Hiroshi Mamitsuka

Prostate cancer is one of the leading causes of cancer-related death in men worldwide. Like many cancers, diagnosis involves expert integration of heterogeneous patient information such as imaging, clinical risk factors, and more. For this…

Image and Video Processing · Electrical Eng. & Systems 2023-10-02 Gregory Holste , Douwe van der Wal , Hans Pinckaers , Rikiya Yamashita , Akinori Mitani , Andre Esteva

The unsupervised and principled diagnosis of multi-scale data is a fundamental obstacle in modern scientific problems from, for instance, weather and climate prediction, neurology, epidemiology, and turbulence. Multi-scale data is…

Dynamical Systems · Mathematics 2026-05-27 Karl Lapo , Sara M. Ichinaga , Nathan Kutz

In the medical domain, acquiring large datasets poses significant challenges due to privacy concerns. Nonetheless, the development of a robust deep-learning model for retinal disease diagnosis necessitates a substantial dataset for…

Computer Vision and Pattern Recognition · Computer Science 2024-09-18 Fatema-E- Jannat , Sina Gholami , Jennifer I. Lim , Theodore Leng , Minhaj Nur Alam , Hamed Tabkhi

Recently developed technologies to generate single-cell genomic data have made a revolutionary impact in the field of biology. Multi-omics assays offer even greater opportunities to understand cellular states and biological processes.…

Genomics · Quantitative Biology 2022-01-19 Stefan Stanojevic , Yijun Li , Lana X. Garmire

Multimodal learning systems often face substantial uncertainty due to noisy data, low-quality labels, and heterogeneous modality characteristics. These issues become especially critical in human-computer interaction settings, where data…

Artificial Intelligence · Computer Science 2025-11-21 Hyo-Jeong Jang

In hospitals, data are siloed to specific information systems that make the same information available under different modalities such as the different medical imaging exams the patient undergoes (CT scans, MRI, PET, Ultrasound, etc.) and…

Computer Vision and Pattern Recognition · Computer Science 2021-02-03 Tristan Sylvain , Francis Dutil , Tess Berthier , Lisa Di Jorio , Margaux Luck , Devon Hjelm , Yoshua Bengio

Imbalance in classification tasks is commonly quantified by the cardinalities of examples across classes. This, however, disregards the presence of redundant examples and inherent differences in the learning difficulties of classes.…

Machine Learning · Computer Science 2026-01-22 Çağrı Eser , Zeynep Sonat Baltacı , Emre Akbaş , Sinan Kalkan

The natural world is abundant with concepts expressed via visual, acoustic, tactile, and linguistic modalities. Much of the existing progress in multimodal learning, however, focuses primarily on problems where the same set of modalities…

Machine Learning · Computer Science 2020-12-08 Paul Pu Liang , Peter Wu , Liu Ziyin , Louis-Philippe Morency , Ruslan Salakhutdinov

Managing fluid balance in dialysis patients is crucial, as improper management can lead to severe complications. In this paper, we propose a multimodal approach that integrates visual features from lung ultrasound images with clinical data…

Image and Video Processing · Electrical Eng. & Systems 2024-10-04 Tianqi Yang , Nantheera Anantrasirichai , Oktay Karakuş , Marco Allinovi , Alin Achim

In this paper, we formulate the new multi-objective coverage (MOC) problem where our goal is to identify a small set of representative samples whose predicted outcomes broadly cover the feasible multi-objective space. This problem is of…

Machine Learning · Computer Science 2026-02-18 Zakaria Shams Siam , Xuefeng Liu , Chong Liu

Current machine learning methods for medical image analysis primarily focus on developing models tailored for their specific tasks, utilizing data within their target domain. These specialized models tend to be data-hungry and often exhibit…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Ece Ozkan , Xavier Boix

The distinct characteristics of multiomics data, including complex interactions within and across biological layers and disease heterogeneity (e.g., heterogeneity in etiology and clinical symptoms), drive us to develop novel designs to…

Machine Learning · Computer Science 2024-11-14 Shan Cong , Zhiling Sang , Hongwei Liu , Haoran Luo , Xin Wang , Hong Liang , Jie Hao , Xiaohui Yao

In recent years, multimodal medical data-based survival analysis has attracted much attention. However, real-world datasets often suffer from the problem of incomplete modality, where some patient modality information is missing due to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yi Yin , Yuntao Shou , Zao Dai , Yun Peng , Tao Meng , Wei Ai , Keqin Li

Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

Unsupervised pre-training has emerged as a transformative paradigm, displaying remarkable advancements in various domains. However, the susceptibility to domain shift, where pre-training data distribution differs from fine-tuning, poses a…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Abhiroop Talasila , Maitreya Maity , U. Deva Priyakumar

Histology analysis of the tumor micro-environment integrated with genomic assays is the gold standard for most cancers in modern medicine. This paper proposes a Gene-induced Multimodal Pre-training (GiMP) framework, which jointly…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Ting Jin , Xingran Xie , Renjie Wan , Qingli Li , Yan Wang