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This paper investigates the MM dynamics approach proposed by Han et al. (2022) for multi-modal fusion in biomedical classification tasks. The MM dynamics algorithm integrates feature-level and modality-level informativeness to dynamically…

Machine Learning · Computer Science 2024-11-04 Laura Wenderoth

Many scientific questions in biomedical, environmental, and psychological research involve understanding the effects of multiple factors on outcomes. While factorial experiments are ideal for this purpose, randomized controlled treatment…

Methodology · Statistics 2025-12-03 Ruoqi Yu , Peng Ding

Multimodal data modeling has emerged as a powerful approach in clinical research, enabling the integration of diverse data types such as imaging, genomics, wearable sensors, and electronic health records. Despite its potential to improve…

Identifying the mutations that drive cancer growth is key in clinical decision making and precision oncology. As driver mutations confer selective advantage and thus have an increased likelihood of occurrence, frequency-based statistical…

Genomics · Quantitative Biology 2021-05-04 Adnan Akbar , Andrey Solovyev , John W Cassidy , Nirmesh Patel , Harry W Clifford

In vitro fertilization (IVF) comprises a sequence of interventions concerned with the creation and culture of embryos which are then transferred to the patient's uterus. While the clinically important endpoint is birth, the responses to…

Applications · Statistics 2020-10-21 Jack Wilkinson , Stephen A Roberts , Andy Vail

Polypharmacy, the concurrent use of multiple drugs to treat a single condition, is common in patients managing multiple or complex conditions. However, as more drugs are added to the treatment plan, the risk of adverse drug events (ADEs)…

Machine Learning · Computer Science 2025-06-12 Natalie Wang , Casey Overby Taylor

Mass cytometry technology enables the simultaneous measurement of over 40 proteins on single cells. This has helped immunologists to increase their understanding of heterogeneity, complexity, and lineage relationships of white blood cells.…

Existing datasets for attribute value extraction (AVE) predominantly focus on explicit attribute values while neglecting the implicit ones, lack product images, are often not publicly available, and lack an in-depth human inspection across…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Henry Peng Zou , Vinay Samuel , Yue Zhou , Weizhi Zhang , Liancheng Fang , Zihe Song , Philip S. Yu , Cornelia Caragea

A class of multivariate mixed survival models for continuous and discrete time with a complex covariance structure is introduced in a context of quantitative genetic applications. The methods introduced can be used in many applications in…

Applications · Statistics 2014-05-06 Rafael Pimentel Maia , Per Madsen , Rodrigo Labouriau

The progression of deep learning and the widespread adoption of sensors have facilitated automatic multi-view fusion (MVF) about the cardiovascular system (CVS) signals. However, prevalent MVF model architecture often amalgamates CVS…

Machine Learning · Computer Science 2024-06-14 Qihan Hu , Daomiao Wang , Hong Wu , Jian Liu , Cuiwei Yang

In many longitudinal microarray studies, the gene expression levels in a random sample are observed repeatedly over time under two or more conditions. The resulting time courses are generally very short, high-dimensional, and may have…

Applications · Statistics 2013-02-26 Maurice Berk , Cheryl Hemingway , Michael Levin , Giovanni Montana

Radiogenomics is an emerging field in cancer research that combines medical imaging data with genomic data to predict patients clinical outcomes. In this paper, we propose a multivariate sparse group lasso joint model to integrate imaging…

Methodology · Statistics 2022-06-06 Tiantian Zeng , Md Selim , Jie Zhang , Arnold Stromberg , Jin Chen , Chi Wang

Optimal data detection in massive multiple-input multiple-output (MIMO) systems often requires prohibitively high computational complexity. A variety of detection algorithms have been proposed in the literature, offering different…

Econometrics · Economics 2025-07-02 Yong Li , Sushanta K. Mallick , Tao Zeng , Junxing Zhang

We propose a deep mixture of multimodal hierarchical variational auto-encoders called MMHVAE that synthesizes missing images from observed images in different modalities. MMHVAE's design focuses on tackling four challenges: (i) creating a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Reuben Dorent , Nazim Haouchine , Alexandra Golby , Sarah Frisken , Tina Kapur , William Wells

Accurate protein function prediction requires integrating heterogeneous intrinsic signals (e.g., sequence and structure) with noisy extrinsic contexts (e.g., protein-protein interactions and GO term annotations). However, two key challenges…

Machine Learning · Computer Science 2025-10-28 Runjie Zheng , Zhen Wang , Anjie Qiao , Jiancong Xie , Jiahua Rao , Yuedong Yang

In a multiple measurement vector problem (MMV), where multiple signals share a common sparse support and are sampled by a common sensing matrix, we can expect joint sparsity to enable a further reduction in the number of required…

Information Theory · Computer Science 2015-06-03 Jong Min Kim , Ok Kyun Lee , Jong Chul Ye

Pathology tests are central to modern healthcare in terms of diagnosis and patient management. Aggregated pathology results provide opportunities for research into fundamental and applied questions in health and medicine, but data analytic…

Applications · Statistics 2022-05-05 N. Menon , B. A. Lidbury , A. M. Richardson

Accumulated clinical studies show that microbes living in humans interact closely with human hosts, and get involved in modulating drug efficacy and drug toxicity. Microbes have become novel targets for the development of antibacterial…

Quantitative Methods · Quantitative Biology 2021-08-16 Lei Deng , Yibiao Huang , Xuejun Liu , Hui Liu

Human perception is inherently multimodal. We integrate, for instance, visual, proprioceptive and tactile information into one experience. Hence, multimodal learning is of importance for building robotic systems that aim at robustly…

Machine Learning · Computer Science 2024-11-04 Carlotta Langer , Yasmin Kim Georgie , Ilja Porohovoj , Verena Vanessa Hafner , Nihat Ay

We propose a Bayesian modeling framework for jointly analyzing multiple functional responses of different types (e.g. binary and continuous data). Our approach is based on a multivariate latent Gaussian process and models the dependence…

Methodology · Statistics 2016-01-12 Beth A. Tidemann-Miller , Brian J. Reich , Ana-Maria Staicu
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