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Despite the remarkable success of deep learning in medical imaging analysis, medical image segmentation remains challenging due to the scarcity of high-quality labeled images for supervision. Further, the significant domain gap between…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Hedda Cohen Indelman , Elay Dahan , Angeles M. Perez-Agosto , Carmit Shiran , Doron Shaked , Nati Daniel

Medical image segmentation has achieved remarkable success through the continuous advancement of UNet-based and Transformer-based foundation backbones. However, clinical diagnosis in the real world often requires integrating domain…

Computer Vision and Pattern Recognition · Computer Science 2025-04-11 Siyuan Dai , Kai Ye , Guodong Liu , Haoteng Tang , Liang Zhan

Segment anything model (SAM) has emerged as the leading approach for zero-shot learning in segmentation tasks, offering the advantage of avoiding pixel-wise annotations. It is particularly appealing in medical image segmentation, where the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-29 Ziyi Huang , Hongshan Liu , Haofeng Zhang , Xueshen Li , Haozhe Liu , Fuyong Xing , Andrew Laine , Elsa Angelini , Christine Hendon , Yu Gan

The ability to quickly annotate medical imaging data plays a critical role in training deep learning frameworks for segmentation. Doing so for image volumes or video sequences is even more pressing as annotating these is particularly…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Laurent Lejeune , Raphael Sznitman

Accurate annotation of cutaneous neoplasm biopsies represents a major challenge due to their wide morphological variability, overlapping histological patterns, and the subtle distinctions between benign and malignant lesions.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Santiago Moreno , Pablo Meseguer , Rocío del Amor , Valery Naranjo

Existing segmentation models trained on a single medical imaging dataset often lack robustness when encountering unseen organs or tumors. Developing a robust model capable of identifying rare or novel tumor categories not present during…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Rong Wu , Ziqi Chen , Liming Zhong , Heng Li , Hai Shu

Medical image analysis continues to hold interesting challenges given the subtle characteristics of certain diseases and the significant overlap in appearance between diseases. In this work, we explore the concept of self-attention for…

Image and Video Processing · Electrical Eng. & Systems 2021-10-13 Hossein Aboutalebi , Maya Pavlova , Hayden Gunraj , Mohammad Javad Shafiee , Ali Sabri , Amer Alaref , Alexander Wong

In recent years, the denoising diffusion model has achieved remarkable success in image segmentation modeling. With its powerful nonlinear modeling capabilities and superior generalization performance, denoising diffusion models have…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Weiping Ding , Sheng Geng , Haipeng Wang , Jiashuang Huang , Tianyi Zhou

The advancement of Zero-Shot Learning in the medical domain has been driven forward by using pre-trained models on large-scale image-text pairs, focusing on image-text alignment. However, existing methods primarily rely on cosine similarity…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Haoran Lai , Qingsong Yao , Zihang Jiang , Rongsheng Wang , Zhiyang He , Xiaodong Tao , S. Kevin Zhou

Automatic medical image segmentation plays a critical role in scientific research and medical care. Existing high-performance deep learning methods typically rely on large training datasets with high-quality manual annotations, which are…

Image and Video Processing · Electrical Eng. & Systems 2021-11-17 Shanshan Wang , Cheng Li , Rongpin Wang , Zaiyi Liu , Meiyun Wang , Hongna Tan , Yaping Wu , Xinfeng Liu , Hui Sun , Rui Yang , Xin Liu , Jie Chen , Huihui Zhou , Ismail Ben Ayed , Hairong Zheng

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

Few-shot video object segmentation aims to reduce annotation costs; however, existing methods still require abundant dense frame annotations for training, which are scarce in the medical domain. We investigate an extremely low-data regime…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Zixuan Zheng , Yilei Shi , Chunlei Li , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou

Annotation variability remains a substantial challenge in medical image segmentation, stemming from ambiguous imaging boundaries and diverse clinical expertise. Traditional deep learning methods producing single deterministic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Han Zhang , Xiangde Luo , Yong Chen , Kang Li

Recently, automated medical image segmentation methods based on deep learning have achieved great success. However, they heavily rely on large annotated datasets, which are costly and time-consuming to acquire. Few-shot learning aims to…

Artificial Intelligence · Computer Science 2024-08-20 Jiayu Huo , Ruiqiang Xiao , Haotian Zheng , Yang Liu , Sebastien Ourselin , Rachel Sparks

Despite significant advancements, segmentation based on deep neural networks in medical and surgical imaging faces several challenges, two of which we aim to address in this work. First, acquiring complete pixel-level segmentation labels…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Junwen Wang , Zhonghao Wang , Oscar MacCormac , Jonathan Shapey , Tom Vercauteren

Medical image segmentation is crucial for clinical decision-making, but the scarcity of annotated data presents significant challenges. Few-shot segmentation (FSS) methods show promise but often require training on the target domain and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Lin Zhao , Xiao Chen , Eric Z. Chen , Yikang Liu , Terrence Chen , Shanhui Sun

Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Tyler Ward , Meredith K. Owen , O'Kira Coleman , Brian Noehren , Abdullah-Al-Zubaer Imran

Training robust learning algorithms across different medical imaging modalities is challenging due to the large domain gap. Unsupervised domain adaptation (UDA) mitigates this problem by using annotated images from the source domain and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Chen Li , Meilong Xu , Xiaoling Hu , Weimin Lyu , Chao Chen

We propose an unsupervised image segmentation method using features from pre-trained text-to-image diffusion models. Inspired by classic spectral clustering approaches, we construct adjacency matrices from self-attention layers between…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Daniela Ivanova , Marco Aversa , Paul Henderson , John Williamson

The medical imaging literature has witnessed remarkable progress in high-performing segmentation models based on convolutional neural networks. Despite the new performance highs, the recent advanced segmentation models still require large,…

Image and Video Processing · Electrical Eng. & Systems 2020-02-13 Nima Tajbakhsh , Laura Jeyaseelan , Qian Li , Jeffrey Chiang , Zhihao Wu , Xiaowei Ding