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Large Language Models (LLMs) have shown remarkable capabilities in general domains but often struggle with tasks requiring specialized knowledge. Conventional Retrieval-Augmented Generation (RAG) techniques typically retrieve external…

Computation and Language · Computer Science 2025-02-20 Yucheng Shi , Tianze Yang , Canyu Chen , Quanzheng Li , Tianming Liu , Xiang Li , Ninghao Liu

Large Language Models (LLMs) have demonstrated significant potential in medical Question Answering (QA), yet they remain prone to hallucinations and ungrounded reasoning, limiting their reliability in high-stakes clinical scenarios. While…

Information Retrieval · Computer Science 2026-01-09 Jessica Ryan , Alexander I. Gumilang , Robert Wiliam , Derwin Suhartono

We present \textbf{SymbioticRAG}, a novel framework that fundamentally reimagines Retrieval-Augmented Generation~(RAG) systems by establishing a bidirectional learning relationship between humans and machines. Our approach addresses two…

Information Retrieval · Computer Science 2025-05-06 Qiang Sun , Tingting Bi , Sirui Li , Eun-Jung Holden , Paul Duuring , Kai Niu , Wei Liu

Natural Language Processing (NLP) and Voice Recognition agents are rapidly evolving healthcare by enabling efficient, accessible, and professional patient support while automating grunt work. This report serves as my self project wherein…

Audio and Speech Processing · Electrical Eng. & Systems 2025-02-21 Kabir Kumar

Recent proprietary large language models (LLMs), such as GPT-4, have achieved a milestone in tackling diverse challenges in the biomedical domain, ranging from multiple-choice questions to long-form generations. To address challenges that…

Computation and Language · Computer Science 2024-06-19 Minbyul Jeong , Jiwoong Sohn , Mujeen Sung , Jaewoo Kang

The deployment of Large Language Models (LLMs) in mental health counseling faces the dual challenges of hallucinations and lack of empathy. While the former may be mitigated by RAG (retrieval-augmented generation) by anchoring answers in…

Computation and Language · Computer Science 2026-01-06 Md Abdullah Al Kafi , Raka Moni , Sumit Kumar Banshal

Artificial Intelligence (AI) has demonstrated significant potential in healthcare, particularly in disease diagnosis and treatment planning. Recent progress in Medical Large Vision-Language Models (Med-LVLMs) has opened up new possibilities…

Machine Learning · Computer Science 2025-03-04 Peng Xia , Kangyu Zhu , Haoran Li , Tianze Wang , Weijia Shi , Sheng Wang , Linjun Zhang , James Zou , Huaxiu Yao

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Achieving true human-like ability to conduct a conversation remains an elusive goal for open-ended dialogue systems. We posit this is because extant approaches towards natural language generation (NLG) are typically construed as end-to-end…

Seed implant brachytherapy (SIBT) is an effective cancer treatment modality; however, clinical planning often relies on manual adjustment of objective function weights, leading to inefficiencies and suboptimal results. This study proposes…

Medical Physics · Physics 2025-09-11 Zhuo Xiao , Qinglong Yao , Jingjing Wang , Fugen Zhou , Bo Liu , Haitao Sun , Zhe Ji , Yuliang Jiang , Junjie Wang , Qiuwen Wu

Conversational systems are now capable of producing impressive and generally relevant responses. However, we have no visibility nor control of the socio-emotional strategies behind state-of-the-art Large Language Models (LLMs), which poses…

Computation and Language · Computer Science 2024-12-09 Lorraine Vanel , Ariel R. Ramos Vela , Alya Yacoubi , Chloé Clavel

We present Tell Me, a mental well-being system that leverages advances in large language models to provide accessible, context-aware support for users and researchers. The system integrates three components: (i) a retrieval-augmented…

Computation and Language · Computer Science 2025-11-19 Trishala Jayesh Ahalpara

Single-step retrieval-augmented generation (RAG) provides an efficient way to incorporate external information for simple question answering tasks but struggles with complex questions. Agentic RAG extends this paradigm by replacing…

Computation and Language · Computer Science 2026-05-08 Yijia Zheng , Marcel Worring

The increasing administrative burden of medical documentation, particularly through Electronic Health Records (EHR), significantly reduces the time available for direct patient care and contributes to physician burnout. To address this…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-25 Hui Yi Leong , Yi Fan Gao , Shuai Ji , Bora Kalaycioglu , Uktu Pamuksuz

Despite the wide adoption of Large Language Models (LLM)s, clinical decision support systems face a critical challenge: achieving high predictive accuracy while generating explanations aligned with the predictions. Current approaches suffer…

Artificial Intelligence · Computer Science 2026-05-07 H M Quamran Hasan , Housam Khalifa Bashier , Jiayi Dai , Mi-Young Kim , Randy Goebel

Clinical note generation aims to produce free-text summaries of a patient's condition and diagnostic process, with discharge instructions being a representative long-form example. While recent LLM-based methods pre-trained on general…

Computation and Language · Computer Science 2025-08-12 Lo Pang-Yun Ting , Chengshuai Zhao , Yu-Hua Zeng , Yuan Jee Lim , Kun-Ta Chuang , Huan Liu

Patient matching is the process of linking patients to appropriate clinical trials by accurately identifying and matching their medical records with trial eligibility criteria. We propose LLM-Match, a novel framework for patient matching…

Computation and Language · Computer Science 2025-03-26 Xiaodi Li , Shaika Chowdhury , Chung Il Wi , Maria Vassilaki , Xiaoke Liu , Terence T Sio , Owen Garrick , Young J Juhn , James R Cerhan , Cui Tao , Nansu Zong

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Large language models (LLMs) have shown substantial progress in natural language understanding and generation, proving valuable especially in the medical field. Despite advancements, challenges persist due to the complexity and diversity…

Computation and Language · Computer Science 2024-10-18 Yusheng Liao , Shuyang Jiang , Zhe Chen , Yanfeng Wang , Yu Wang

Retrieval-augmented Generation (RAG) has demonstrated potential in enhancing medical question-answering systems through the integration of large language models (LLMs) with external medical literature. LLMs can retrieve relevant medical…

Computation and Language · Computer Science 2025-10-29 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bin Qin