Related papers: An AI-enabled dual-hormone model predictive contro…
Pramlintide's capability to delay gastric emptying has motivated its use in artificial pancreas systems, accompanying insulin as a control action. Due to the scarcity of pramlintide simulation models in the literature, in silico testing of…
We present the design and \textit{in-silico} evaluation of a closed-loop insulin delivery algorithm to treat type 1 diabetes (T1D) consisting in a data-driven multi-step-ahead blood glucose (BG) predictor integrated into a Linear…
In this work, we present a switching nonlinear model predictive control (NMPC) algorithm for a dual-hormone artificial pancreas (AP), and we use maximum likelihood estimation (MLE) to identify model parameters. A dual-hormone AP consists of…
Background and objective: Hybrid automated insulin delivery (hAID) systems represent the most advanced therapy for type 1 diabetes (T1D). Current systems rely on linear or linearized models of glucose homeostasis, which may compromise…
People with diabetes need insulin delivery to effectively manage their blood glucose levels, especially after meals, because their bodies either do not produce enough insulin or cannot fully utilize it. Accurate insulin delivery starts with…
Background: Type 2 diabetes (T2D) is a prevalent chronic disease with a significant risk of serious health complications and negative impacts on the quality of life. Given the impact of individual characteristics and lifestyle on the…
The growing worldwide incidence of diabetes requires more effective approaches for managing blood glucose levels. Insulin delivery systems have advanced significantly, with artificial intelligence (AI) playing a key role in improving their…
Identifying type 2 diabetes mellitus can be challenging, particularly for primary care physicians. Clinical decision support systems incorporating artificial intelligence (AI-CDSS) can assist medical professionals in diagnosing type 2…
Even though model predictive control (MPC) is currently the main algorithm for insulin control in the artificial pancreas (AP), it usually requires complex online optimizations, which are infeasible for resource-constrained medical devices.…
People living with Type 1 Diabetes (T1D) lose the ability to produce insulin naturally. To compensate, they inject synthetic insulin. One common way to inject insulin is through automated insulin delivery systems, which use sensors to…
Postprandial hyperglycemia, marked by the blood glucose level exceeding the normal range after consuming a meal, is a critical indicator of progression toward type 2 diabetes in people with prediabetes and in healthy individuals. A key…
We present a fully closed-loop design for an artificial pancreas (AP) which regulates the delivery of insulin for the control of Type I diabetes. Our AP controller operates in a fully automated fashion, without requiring any manual…
Training Neural Networks (NNs) to behave as Model Predictive Control (MPC) algorithms is an effective way to implement them in constrained embedded devices. By collecting large amounts of input-output data, where inputs represent system…
People with Type 1 diabetes (T1D) require regular exogenous infusion of insulin to maintain their blood glucose concentration in a therapeutically adequate target range. Although the artificial pancreas and continuous glucose monitoring…
Calculating mealtime insulin doses poses a significant challenge for individuals with Type 1 Diabetes (T1D). Doses should perfectly compensate for expected post-meal glucose excursions, requiring a profound understanding of the individual's…
Objective: Numerous glucose prediction algorithm have been proposed to empower type 1 diabetes (T1D) management. Most of these algorithms only account for input such as glucose, insulin and carbohydrate, which limits their performance.…
Type 1 diabetes (T1D) management can be significantly enhanced through the use of predictive machine learning (ML) algorithms, which can mitigate the risk of adverse events like hypoglycemia. Hypoglycemia, characterized by blood glucose…
AI procedures joined with wearable gadgets can convey exact transient blood glucose level forecast models. Also, such models can learn customized glucose-insulin elements dependent on the sensor information gathered by observing a few parts…
Sustained high levels of blood glucose in type 2 diabetes (T2DM) can have disastrous long-term health consequences. An essential component of clinical interventions for T2DM is monitoring dietary intake to keep plasma glucose levels within…
This work presents a Model Predictive Control (MPC) for the artificial pancreas, which is able to autonomously manage basal insulin injections in type 1 diabetic patients. Specifically, the MPC goal is to maintain the patients' blood…