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Causal processes in biomedicine may contain cycles, evolve over time or differ between populations. However, many graphical models cannot accommodate these conditions. We propose to model causation using a mixture of directed cyclic graphs…

Machine Learning · Statistics 2020-09-08 Eric V. Strobl

We consider a a collection of categorical random variables. Of special interest is the causal effect on an outcome variable following an intervention on another variable. Conditionally on a Directed Acyclic Graph (DAG), we assume that the…

Methodology · Statistics 2023-06-29 Federico Castelletti , Guido Consonni , Marco Luigi Della Vedova

Unobserved confounding is a fundamental challenge for estimating causal effects. To address unobserved confounding, recent literature has turned to two different approaches -- proxy variables and the use of multiple treatments. The first…

Methodology · Statistics 2026-05-20 Aytijhya Saha , Stephen Bates , Devavrat Shah

In online advertising, marketing mix modeling (MMM) is employed to predict the gross merchandise volume (GMV) of brand shops and help decision-makers to adjust the budget allocation of various advertising channels. Traditional MMM methods…

Artificial Intelligence · Computer Science 2024-06-25 Chang Gong , Di Yao , Lei Zhang , Sheng Chen , Wenbin Li , Yueyang Su , Jingping Bi

The importance of Synthetic Data Generation (SDG) has increased significantly in domains where data quality is poor or access is limited due to privacy and regulatory constraints. One such domain is recruitment, where publicly available…

Machine Learning · Computer Science 2025-11-24 Andrea Iommi , Antonio Mastropietro , Riccardo Guidotti , Anna Monreale , Salvatore Ruggieri

Classical machine learning techniques often struggle with overfitting and unreliable predictions when exposed to novel conditions. Introducing causality into the modelling process offers a promising way to mitigate these challenges by…

Computational Engineering, Finance, and Science · Computer Science 2025-05-28 David Zapata Gonzalez , Marcel Meyer , Oliver Mueller

Bivariate causal direction identification is a fundamental and vital problem in the causal inference field. Among binary causal methods, most methods based on additive noise only use one single causal mechanism to construct a causal model.…

Artificial Intelligence · Computer Science 2025-07-30 Saixiong Liu , Yuhua Qian , Jue Li , Honghong Cheng , Feijiang Li

Despite significant advancements in causal research on graphs and its application to cracking label imbalance, the role of edge features in detecting the causal effects within graphs has been largely overlooked, leaving existing methods…

Machine Learning · Computer Science 2025-01-08 Fengrui Zhang , Yujia Yin , Hongzong Li , Yifan Chen , Tianyi Qu

Causal inference and model interpretability are gaining increasing attention, particularly in the biomedical domain. Despite recent advance, decorrelating features in nonlinear environments with human-interpretable representations remains…

Machine Learning · Computer Science 2024-11-12 Junda Wang , Weijian Li , Han Wang , Hanjia Lyu , Caroline P. Thirukumaran , Addisu Mesfin , Hong Yu , Jiebo Luo

Unobserved confounding is one of the main challenges when estimating causal effects. We propose a causal reduction method that, given a causal model, replaces an arbitrary number of possibly high-dimensional latent confounders with a single…

Machine Learning · Statistics 2023-02-24 Maximilian Ilse , Patrick Forré , Max Welling , Joris M. Mooij

We consider the problem of predicting perturbation effects via causal models. In many applications, it is a priori unknown which mechanisms of a system are modified by an external perturbation, even though the features of the perturbation…

Machine Learning · Computer Science 2025-07-02 Nora Schneider , Lars Lorch , Niki Kilbertus , Bernhard Schölkopf , Andreas Krause

Leveraging deep learning for causal discovery in time series remains challenging because existing neural methods predominantly rely on component-wise architectures that fail to capture shared system dynamics or employ decoupled post-hoc…

Machine Learning · Computer Science 2026-05-11 Omar Muhammad , Pasupuleti Dhruv Shivkant , Deepak N. Subramani

Structural Causal Models (SCMs) provide a popular causal modeling framework. In this work, we show that SCMs are not flexible enough to give a complete causal representation of dynamical systems at equilibrium. Instead, we propose a…

Artificial Intelligence · Computer Science 2019-08-07 Tineke Blom , Stephan Bongers , Joris M. Mooij

Many large-scale applications can be elegantly represented using graph structures. Their scalability, however, is often limited by the domain knowledge required to apply them. To address this problem, we propose a novel Causal Temporal…

Machine Learning · Computer Science 2023-03-20 Abigail Langbridge , Fearghal O'Donncha , Amadou Ba , Fabio Lorenzi , Christopher Lohse , Joern Ploennigs

Modeling causal relationships in graph representation learning remains a fundamental challenge. Existing approaches often draw on theories and methods from causal inference to identify causal subgraphs or mitigate confounders. However, due…

Machine Learning · Computer Science 2026-04-13 Hang Gao , Kunyu Li , Huang Hong , Baoquan Cui , Fengge Wu

Method validation and study design in causal inference rely on synthetic data with known counterfactuals. Existing simulators trade off distributional realism, the ability to capture mixed-type and multimodal tabular data, against causal…

Methodology · Statistics 2026-03-05 Qi Zhang , Harsh Parikh , Ashley Naimi , Razieh Nabi , Christopher Kim , Timothy Lash

Causal effect identification using causal graphs is a fundamental challenge in causal inference. While extensive research has been conducted in this area, most existing methods assume the availability of fully specified directed acyclic…

Artificial Intelligence · Computer Science 2025-09-03 Simon Ferreira , Charles K. Assaad

Medical multimodal representation learning aims to integrate heterogeneous clinical data into unified patient representations to support predictive modeling, which remains an essential yet challenging task in the medical data mining…

Machine Learning · Computer Science 2025-09-09 Xiaoguang Zhu , Lianlong Sun , Yang Liu , Pengyi Jiang , Uma Srivatsa , Nipavan Chiamvimonvat , Vladimir Filkov

Trajectory anomaly detection, aiming to estimate the anomaly risk of trajectories given the Source-Destination (SD) pairs, has become a critical problem for many real-world applications. Existing solutions directly train a generative model…

Machine Learning · Computer Science 2024-12-30 Wenbin Li , Di Yao , Chang Gong , Xiaokai Chu , Quanliang Jing , Xiaolei Zhou , Yuxuan Zhang , Yunxia Fan , Jingping Bi

Discovering causal relations from observational time series without making the stationary assumption is a significant challenge. In practice, this challenge is common in many areas, such as retail sales, transportation systems, and medical…

Machine Learning · Computer Science 2024-07-11 Shanyun Gao , Raghavendra Addanki , Tong Yu , Ryan A. Rossi , Murat Kocaoglu