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Existing contrastive language-image pre-training aims to learn a joint representation by matching abundant image-text pairs. However, the number of image-text pairs in medical datasets is usually orders of magnitude smaller than that in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-04 Jiarun Liu , Hong-Yu Zhou , Cheng Li , Weijian Huang , Hao Yang , Yong Liang , Shanshan Wang

Vision-Language Models such as CLIP exhibit strong zero-shot recognition capability by aligning images with textual concepts, yet they often underperform on multi-label recognition where multiple objects co-exist. A key bottleneck is that…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Akang Wang , Xili Deng , Zhanxuan Hu , Yi Zhao , Yonghang Tai , Huafeng Li

Image-based profiling techniques have become increasingly popular over the past decade for their applications in target identification, mechanism-of-action inference, and assay development. These techniques have generated large datasets of…

Biomolecules · Quantitative Biology 2023-06-28 Cuong Q. Nguyen , Dante Pertusi , Kim M. Branson

Multi-modal learning relates information across observation modalities of the same physical phenomenon to leverage complementary information. Most multi-modal machine learning methods require that all the modalities used for training are…

Machine Learning · Computer Science 2021-03-10 Vandana Rajan , Alessio Brutti , Andrea Cavallaro

With the rapid advancement of pathology foundation models (FMs), the representation learning of whole slide images (WSIs) attracts increasing attention. Existing studies develop high-quality patch feature extractors and employ carefully…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Yuxuan Chen , Jiawen Li , Jiali Hu , Xitong Ling , Tian Guan , Anjia Han , Yonghong He

As digital medical imaging becomes more prevalent and archives increase in size, representation learning exposes an interesting opportunity for enhanced medical decision support systems. On the other hand, medical imaging data is often…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Eduardo Pinho , Carlos Costa

Multi-modality image fusion aims at fusing modality-specific (complementarity) and modality-shared (correlation) information from multiple source images. To tackle the problem of the neglect of inter-feature relationships, high-frequency…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Xiaoli Zhang , Liying Wang , Libo Zhao , Xiongfei Li , Siwei Ma

Multi-modal learning has shown exceptional performance in various tasks, especially in medical applications, where it integrates diverse medical information for comprehensive diagnostic evidence. However, there still are several challenges…

Machine Learning · Computer Science 2024-11-19 Lin Fan , Yafei Ou , Cenyang Zheng , Pengyu Dai , Tamotsu Kamishima , Masayuki Ikebe , Kenji Suzuki , Xun Gong

Adversarial robustness research primarily focuses on L_p perturbations, and most defenses are developed with identical training-time and test-time adversaries. However, in real-world applications developers are unlikely to have access to…

Survival prediction is a complex ordinal regression task that aims to predict the survival coefficient ranking among a cohort of patients, typically achieved by analyzing patients' whole slide images. Existing deep learning approaches…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Minghao Han , Xukun Zhang , Dingkang Yang , Tao Liu , Haopeng Kuang , Jinghui Feng , Lihua Zhang

Medical multimodal learning faces significant challenges with missing modalities prevalent in clinical practice. Existing approaches assume equal contribution of modality and random missing patterns, neglecting inherent uncertainty in…

Machine Learning · Computer Science 2026-01-30 Linxiao Gong , Yang Liu , Lianlong Sun , Yulai Bi , Jing Liu , Xiaoguang Zhu

Multi-modal entity alignment (MMEA) aims to discover identical entities across different knowledge graphs (KGs) whose entities are associated with relevant images. However, current MMEA algorithms rely on KG-level modality fusion strategies…

Artificial Intelligence · Computer Science 2023-08-01 Zhuo Chen , Jiaoyan Chen , Wen Zhang , Lingbing Guo , Yin Fang , Yufeng Huang , Yichi Zhang , Yuxia Geng , Jeff Z. Pan , Wenting Song , Huajun Chen

Large language models applied to vast biological datasets have the potential to transform biology by uncovering disease mechanisms and accelerating drug development. However, current models are often siloed, trained separately on…

As deep neural networks become more adept at traditional tasks, many of the most exciting new challenges concern multimodality---observations that combine diverse types, such as image and text. In this paper, we introduce a family of…

Machine Learning · Computer Science 2019-12-12 Mike Wu , Noah Goodman

Multi-Modal Entity Alignment (MMEA) aims to retrieve equivalent entities from different Multi-Modal Knowledge Graphs (MMKGs), a critical information retrieval task. Existing studies have explored various fusion paradigms and consistency…

Multimedia · Computer Science 2025-05-16 Taoyu Su , Jiawei Sheng , Duohe Ma , Xiaodong Li , Juwei Yue , Mengxiao Song , Yingkai Tang , Tingwen Liu

Considering the high computation cost produced in conventional computation fluid dynamic simulations, machine learning methods have been introduced to flow dynamic simulations in recent years. However, most of studies focus mainly on…

Fluid Dynamics · Physics 2020-10-13 M. Cheng , F. Fang , C. C. Pain , I. M. Navon

Recent advances in instruction tuning have led to the development of State-of-the-Art Large Multimodal Models (LMMs). Given the novelty of these models, the impact of visual adversarial attacks on LMMs has not been thoroughly examined. We…

Computer Vision and Pattern Recognition · Computer Science 2023-12-11 Xuanming Cui , Alejandro Aparcedo , Young Kyun Jang , Ser-Nam Lim

Adversarial machine learning is a well-studied field of research where an adversary causes predictable errors in a machine learning algorithm through precise manipulation of the input. Numerous techniques have been proposed to harden…

Computer Vision and Pattern Recognition · Computer Science 2020-03-31 Pratik Vaishnavi , Kevin Eykholt , Atul Prakash , Amir Rahmati

Image matching, which aims to identify corresponding pixel locations between images, is crucial in a wide range of scientific disciplines, aiding in image registration, fusion, and analysis. In recent years, deep learning-based image…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Xingyi He , Hao Yu , Sida Peng , Dongli Tan , Zehong Shen , Hujun Bao , Xiaowei Zhou

Protein-protein interaction (PPI) prediction plays a pivotal role in deciphering cellular functions and disease mechanisms. To address the limitations of traditional experimental methods and existing computational approaches in cross-modal…

Machine Learning · Computer Science 2025-04-29 Shengrui XU , Tianchi Lu , Zikun Wang , Jixiu Zhai