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Intensity-modulated radiation therapy (IMRT) allows for the design of customized, highly-conformal treatments for cancer patients. Creating IMRT treatment plans, however, is a mathematically complex process, which is often tackled in…

Optimization and Control · Mathematics 2022-03-18 Danielle A. Ripsman , Thomas G. Purdie , Timothy C. Y. Chan , Houra Mahmoudzadeh

Over the recent years, the emergence of large language models (LLMs) has given rise to a proliferation of domain-specific models that are intended to reflect the particularities of linguistic context and content as a correlate of the…

Computation and Language · Computer Science 2024-02-20 Chris von Csefalvay

Modern chip design requires multi-objective optimization of timing, power, and area under stringent time-to-market constraints. Although powerful optimization algorithms are integrated into EDA tools, achieving high QoR hinges on effective…

Hardware Architecture · Computer Science 2026-03-17 Yikang ouyang , Yang Luo , Dongsheng Zuo , Yuzhe Ma

We introduce a practical and scalable algorithm (PALMA) for solving one of the fundamental problems of multi-agent systems -- finding matches and allocations -- in unboundedly large settings (e.g., resource allocation in urban environments,…

Multiagent Systems · Computer Science 2022-03-15 Panayiotis Danassis , Aleksei Triastcyn , Boi Faltings

Nowadays, Generative AI (GenAI) reshapes numerous domains by enabling machines to create content across modalities. As GenAI evolves into autonomous agents capable of reasoning, collaboration, and interaction, they are increasingly deployed…

Networking and Internet Architecture · Computer Science 2025-05-20 Yinqiu Liu , Guangyuan Liu , Jiacheng Wang , Ruichen Zhang , Dusit Niyato , Geng Sun , Zehui Xiong , Zhu Han

Large Vision-Language Models (LVLMs) have shown significant potential in assisting medical diagnosis by leveraging extensive biomedical datasets. However, the advancement of medical image understanding and reasoning critically depends on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Guohao Sun , Can Qin , Huazhu Fu , Linwei Wang , Zhiqiang Tao

High-dose-rate (HDR) brachytherapy plays a critical role in the treatment of locally advanced cervical cancer but remains highly dependent on manual treatment planning expertise. The objective of this study is to develop a fully automated…

The advancement of artificial intelligence algorithms has expanded their application to several fields such as the biomedical domain. Artificial intelligence systems, including Large Language Models (LLMs), can be particularly advantageous…

PET theranostics is transforming precision oncology, yet treatment response varies substantially; many patients receiving 177Lu-PSMA radioligand therapy (RLT) for metastatic castration-resistant prostate cancer (mCRPC) fail to respond,…

When aligning large language models (LLMs), their performance on various tasks (such as being helpful, harmless, and honest) depends heavily on the composition of their training data. However, selecting a data mixture that achieves strong…

Machine Learning · Computer Science 2025-06-03 Nicholas E. Corrado , Julian Katz-Samuels , Adithya Devraj , Hyokun Yun , Chao Zhang , Yi Xu , Yi Pan , Bing Yin , Trishul Chilimbi

Low-Rank Adaptation (LoRA) is now the dominant method for parameter-efficient fine-tuning of large language models, but achieving a high-quality adapter often requires systematic hyperparameter tuning because LoRA performance is highly…

Machine Learning · Computer Science 2026-04-13 Jingwei Zuo , Xinze Feng , Zien Liu , Kaijian Wang , Fanjiang Ye , Ye Cao , Zhuang Wang , Yuke Wang

Web agents have emerged as a promising direction to automate Web task completion based on user instructions, significantly enhancing user experience. Recently, Web agents have evolved from traditional agents to Large Language Models…

Computation and Language · Computer Science 2025-03-25 Hongru Cai , Yongqi Li , Wenjie Wang , Fengbin Zhu , Xiaoyu Shen , Wenjie Li , Tat-Seng Chua

Determining the ideal architecture for deep learning models, such as the number of layers and neurons, is a difficult and resource-intensive process that frequently relies on human tuning or computationally costly optimization approaches.…

Artificial Intelligence · Computer Science 2025-04-22 Saad Hameed , Basheer Qolomany , Samir Brahim Belhaouari , Mohamed Abdallah , Junaid Qadir , Ala Al-Fuqaha

While Large Language Models (LLMs) have revolutionized artificial intelligence, fine-tuning LLMs is extraordinarily computationally expensive, preventing smaller businesses and research teams with limited GPU resources from engaging with…

Machine Learning · Computer Science 2025-08-26 Daniel Frees , Aditri Bhagirath , Moritz Bolling

Large language models (LLMs) have been widely used for various tasks and applications. However, LLMs and fine-tuning are limited to the pre-trained data. For example, ChatGPT's world knowledge until 2021 can be outdated or inaccurate. To…

Computation and Language · Computer Science 2025-04-24 Ahsan Bilal , Beiyu Lin

A multitude of industries depend on accurate and reasonable tabular data augmentation for their business processes. Contemporary methodologies in generating tabular data revolve around utilizing Generative Adversarial Networks (GAN) or…

Machine Learning · Computer Science 2025-02-25 Shuo Yang , Chenchen Yuan , Yao Rong , Felix Steinbauer , Gjergji Kasneci

Low-Rank Adaptation (LoRA) has emerged as one of the most widely used parameter-efficient fine-tuning (PEFT) methods for adapting large language models (LLMs) to downstream tasks. While highly effective in single-task settings, it struggles…

Computation and Language · Computer Science 2025-10-14 Bo Cheng , Xu Wang , Jinda Liu , Yi Chang , Yuan Wu

Advancements in large language models (LLMs) allow them to address diverse questions using human-like interfaces. Still, limitations in their training prevent them from answering accurately in scenarios that could benefit from multiple…

Artificial Intelligence · Computer Science 2025-04-09 Yoshitaka Inoue , Tianci Song , Xinling Wang , Augustin Luna , Tianfan Fu

Conventional radiotherapy dose calculation algorithms are often computationally slow and non-differentiable, creating bottlenecks for online adaptive radiotherapy (ART) and limiting end-to-end automatic planning. Deep learning provides…

Background: Modern large language models (LLMs) offer powerful reasoning that converts narratives into structured, taxonomy-aligned data, revealing patterns across planning, delivery, and verification. Embedded as agentic tools, LLMs can…