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We consider Susceptible-Infected-Recovered (SIR) models on dense dynamic random graphs, in which the joint dynamics of vertices and edges are co-evolutionary, i.e., they influence each other bidirectionally. In particular, edges appear and…

Probability · Mathematics 2026-02-17 Simone Baldassarri , Peter Braunsteins , Frank den Hollander , Michel Mandjes

When an infectious disease propagates throughout society, the incidence function may rise at first due to an increase in pathogenicity and then decrease due to inhibitory effects until it reaches saturation. Effective vaccination and…

Dynamical Systems · Mathematics 2023-07-11 Sushil Pathak , G. Shirisha , K. Venkata Ratnam

We investigate a two-strain disease model with amplification to simulate the prevalence of drug-susceptible (s) and drug-resistant (m) disease strains. We model the emergence of drug resistance as a consequence of inadequate treatment, i.e.…

Populations and Evolution · Quantitative Biology 2019-08-22 Md Abdul Kuddus , Michael T. Meehan , Adeshina I. Adekunle , Lisa J. White , Emma S. McBryde

This study examines the behavior of solutions in a multi-patch epidemic model that includes a saturation incidence mechanism. When the fatality rate due to the disease is not null, our findings show that the solutions of the model tend to…

Populations and Evolution · Quantitative Biology 2024-09-19 Yawo Ezunkpe , Cynthia T. Nnolum , Rachidi B. Salako , Shuwen Xue

In this work we review a class of deterministic nonlinear models for the propagation of infectious diseases over contact networks with strongly-connected topologies. We consider network models for susceptible-infected (SI),…

Social and Information Networks · Computer Science 2017-01-13 Wenjun Mei , Shadi Mohagheghi , Sandro Zampieri , Francesco Bullo

We study an S--I type epidemic model in an age-structured population, with mortality due to the disease. A threshold quantity is found that controls the stability of the disease-free equilibrium and guarantees the existence of an endemic…

Analysis of PDEs · Mathematics 2010-02-25 D. Breda , D. Visetti

The study of social networks, and in particular the spread of disease on networks, has attracted considerable recent attention in the physics community. In this paper, we show that a large class of standard epidemiological models, the…

Statistical Mechanics · Physics 2009-11-07 M. E. J. Newman

This work examines the discrete-time networked SIR (susceptible-infected-recovered) epidemic model, where the infection and recovery parameters may be time-varying. We provide a sufficient condition for the SIR model to converge to the set…

Systems and Control · Electrical Eng. & Systems 2021-03-01 Ciyuan Zhang , Humphrey Leung , Brooks Butler , Philip. E. Paré

An epidemic model with distributed time delay is derived to describe the dynamics of infectious diseases with varying immunity. It is shown that solutions are always positive, and the model has at most two steady states: disease-free and…

Chaotic Dynamics · Physics 2012-09-21 K. B. Blyuss , Y. N. Kyrychko

We consider the SEIRS compartment epidemiology model suitable for predicting the evolution of the COVID-19 pandemy in the extreme limiting case of no acquired immunity. The disease-free and endemic fixed points are found and their stability…

Populations and Evolution · Quantitative Biology 2020-12-15 J. M. Ilnytskyi

We propose an epidemic model for the spread of vector-borne diseases. The model, which is built extending the classical susceptible-infected-susceptible model, accounts for two populations -- humans and vectors -- and for cross-contagion…

Systems and Control · Electrical Eng. & Systems 2025-10-21 Lorenzo Zino , Alessandro Casu , Alessandro Rizzo

In this paper we study the diffusion of an SIS-type epidemics on a network under the presence of a random environment, that enters in the definition of the infection rates of the nodes. Accordingly, we model the infection rates in the form…

Probability · Mathematics 2016-07-25 Stefano Bonaccorsi , Stefania Ottaviano

We show that disease transmission models in a spatially heterogeneous environment can have a large number of coexisting endemic equilibria. A general compartmental model is considered to describe the spread of an infectious disease in a…

Classical Analysis and ODEs · Mathematics 2014-04-01 Diána H. Knipl , Gergely Röst

We investigate the long-time dynamics of a SIR epidemic model with infinitely many pathogen variants infecting a homogeneous host population. We show that the basic reproduction number $\mathcal{R}_0$ of the pathogen can be defined in that…

Populations and Evolution · Quantitative Biology 2023-05-11 Jean-Baptiste Burie , Arnaud Ducrot , Quentin Griette

This paper presents a simple continuous-time linear vaccination-based control strategy for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total…

Dynamical Systems · Mathematics 2011-03-28 M. De la Sen , A. Ibeas , S. Alonso-Quesada

The Susceptible-Infected-Susceptible model is a canonical model for emerging disease outbreaks. Such outbreaks are naturally modeled as taking place on networks. A theoretical challenge in network epidemiology is the dynamic correlations…

Physics and Society · Physics 2016-06-29 Chao-Ran Cai , Zhi-Xi Wu , Michael Z. Q. Chen , Petter Holme , Jian-Yue Guan

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

Dynamical Systems · Mathematics 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

This paper investigates the spread of infectious diseases within a networked community by integrating epidemic transmission and public opinion dynamics. We propose a novel discrete-time networked SIS (Susceptible-Infectious-Susceptible)…

Systems and Control · Electrical Eng. & Systems 2025-08-14 Qiulin Xu , Tatsuya Masada , Hideaki Ishii

This study investigates an SEIS PDE model with a free boundary, which captures the dynamics of epidemic transmission, including diseases like COVID-19. This parabolic PDE system is analyzed in a rotationally symmetric domain, and the…

Analysis of PDEs · Mathematics 2025-11-11 Aesol Jeon , Ki-Ahm Lee

We study a competitive infection-age structured SI model between two diseases. The well-posedness of the system is handled by using integrated semigroups theory, while the existence and the stability of disease-free or endemic equilibria…

Analysis of PDEs · Mathematics 2020-09-14 Quentin Richard