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Accelerating imaging speed in optical microscopy is often realized at the expense of image contrast, image resolution, and detection sensitivity- a common predicament for advancing high-speed and high-throughput cellular imaging. We here…
High-Q optical resonators allow label-free detection of individual nanoparticles through perturbation of optical signatures but have practical limitations due to reliance on random diffusion to deliver particles to the sensing region. We…
We report on using a laser Doppler processing of Fourier-domain optical coherence tomography (OCT) data for the assessment of pulsatile blood flow in the choriocapillaris. Signal fluctuations in B-scans recorded at 2 kHz were analyzed by…
Multidimensional coherent spectroscopy (MDCS) is used to separate coherent and incoherent many-body contributions to the population-time dynamics in a GaAs-based semiconductor microcavity encapsulating a single InGaAs quantum well. In a…
Pathological slowing in the electroencephalogram (EEG) is widely investigated for the diagnosis of neurological disorders. Currently, the gold standard for slowing detection is the visual inspection of the EEG by experts, which is…
Multi-channel electrophysiology systems for recording of neuronal activity face significant data throughput limitations, hampering real-time, data-informed experiments. These limitations impact both experimental neurobiology research and…
Transient brain-wide neuroimaging on a microscopic scale is pivotal for brain research, yet current modalities face challenges in meeting such spatiotemporal requirements. Functional ultrasound (fUS) enables transient neurovascular imaging…
Coronary artery disease(CAD) is the most common type of heart disease and the leading cause of death worldwide[1]. A progressive state of this disease marked by plaque rupture and clot formation in the coronary arteries, also known as an…
The Circle of Willis (CoW), vital for ensuring consistent blood flow to the brain, is closely linked to ischemic stroke. Accurate assessment of the CoW is important for identifying individuals at risk and guiding appropriate clinical…
Row column addressed (RCA) transducers present a promising solution for ultrafast volumetric imaging with a reduced channel count and a large field of view. However, RCA-based 3D imaging is fundamentally limited by severe sidelobe artifacts…
Replacing electrons with photons is a compelling route towards light-speed, highly parallel, and low-power artificial intelligence computing. Recently, all-optical diffractive neural deep neural networks have been demonstrated. However, the…
Adequate blood supply is critical for normal brain function. Brain vasculature dysfunctions such as stalled blood flow in cerebral capillaries are associated with cognitive decline and pathogenesis in Alzheimer's disease. Recent advances in…
The reflectometry on Experimental Advanced Superconducting Tokamak (EAST) is undergoing an upgrade for more comprehensive measurement of plasma density profile and fluctuation. The Data Acquisition and Control System (DACS) has been…
A novel ultra-long distributed vibration sensing (DVS) system using forward transmission and coherent detection is proposed and experimentally demonstrated. In the proposed scheme, a pair of multi-span optical fibers are deployed for…
A recently proposed scatter-window and deep learning-based attenuation compensation (AC) method for myocardial perfusion imaging (MPI) by single-photon emission computed tomography (SPECT), namely CTLESS, demonstrated promising performance…
Stochastic computing (SC) is an emerging computing technique that promises high density, low power, and error tolerant solutions. In SC, values are encoded as unary bitstreams and SC arithmetic circuits operate on one or more bitstreams. In…
Discriminative correlation filters (DCF) with deep convolutional features have achieved favorable performance in recent tracking benchmarks. However, most of existing DCF trackers only consider appearance features of current frame, and…
Photon scattering has traditionally limited the ability of near-infrared spectroscopy (NIRS) to extract accurate, layer-specific information from the brain. This limitation restricts its clinical utility for precise neurological monitoring.…
Delineation of the cardiac structures from 2D echocardiographic images is a common clinical task to establish a diagnosis. Over the past decades, the automation of this task has been the subject of intense research. In this paper, we…
Manual operation of microscopes for repetitive tasks in cell biology is a significant bottleneck, consuming invaluable expert time, and introducing human error. Automation is essential, and while Digital Holographic Microscopy (DHM) offers…