English
Related papers

Related papers: Accelerated Medicines Development using a Digital …

200 papers

Optimizing solution-processed organic solar cells is a complex task due to the vast parameter space in organic photovoltaics (OPV). Classical Edisonian or one-variable-at-a-time (OVAT) optimization approaches are laborious, time-consuming,…

Accelerator-based heterogeneous architectures, such as CPU-GPU, CPU-TPU, and CPU-FPGA systems, are widely adopted to support the popular artificial intelligence (AI) algorithms that demand intensive computation. When deployed in real-time…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-20 An Zou , Yuankai Xu , Yinchen Ni , Jintao Chen , Yehan Ma , Jing Li , Christopher Gill , Xuan Zhang , Yier Jin

Despite the extensive use of the agent technology in the Supply Chain Management field, its integration with Advanced Planning and Scheduling (APS) tools still represents a promising field with several open research questions. Specifically,…

Multiagent Systems · Computer Science 2011-07-19 Luis Antonio de Santa-Eulalia , Sophie D'Amours , Jean-Marc Frayret

Application autotuning is a promising path investigated in literature to improve computation efficiency. In this context, the end-users define high-level requirements and an autonomic manager is able to identify and seize optimization…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-21 Tomas Martinovic , Davide Gadioli , Gianluca Palermo , Cristina Silvano

Data-Driven Product Development (DDPD) leverages data to learn the relationship between product design specifications and resulting properties. To discover improved designs, we train a neural network on past experiments and apply Projected…

Machine Learning · Computer Science 2026-01-06 Andrea Thomas Nava , Lijo Johny , Fabio Azzalini , Johannes Schneider , Arianna Casanova

While drug discovery is vital for human health, the process remains inefficient. Medicinal chemists must navigate a vast protein space to identify target proteins that meet three criteria: physical and functional interactions, therapeutic…

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Due to the rapid development of online food ordering platforms and rocketing growth of demand, the market is about to saturate soon, and the future trend is to seek efficient utilization of resources. Specifically speaking, food company…

Applications · Statistics 2020-02-06 Hanyi Luo , Mengzhan Liufu , Dongrong Li

Large language models are redefining software engineering by implementing AI-powered techniques throughout the whole software development process, including requirement gathering, software architecture, code generation, testing, and…

Software Engineering · Computer Science 2024-06-11 Malik Abdul Sami , Muhammad Waseem , Zeeshan Rasheed , Mika Saari , Kari Systä , Pekka Abrahamsson

Modern scientific discovery increasingly relies on high-performance computing for complex modeling and simulation. A key challenge in improving parallel program performance is efficiently mapping tasks to processors and data to memory, a…

Machine Learning · Computer Science 2025-06-02 Anjiang Wei , Allen Nie , Thiago S. F. X. Teixeira , Rohan Yadav , Wonchan Lee , Ke Wang , Alex Aiken

The convergence of artificial intelligence and materials science presents a transformative opportunity, but achieving true acceleration in discovery requires moving beyond task-isolated, fine-tuned models toward agentic systems that plan,…

Digital Twin (DT) technology has emerged as a transformative approach in healthcare, but its application in personalized patient care remains limited. This paper aims to present a practical implementation of DT in the management of chronic…

Quantitative Methods · Quantitative Biology 2025-07-17 Javad M Alizadeh , Mukesh K Patel , Huanmei Wu

Molecular optimization is a crucial yet complex and time-intensive process that often acts as a bottleneck for drug development. Traditional methods rely heavily on trial and error, making multi-objective optimization both time-consuming…

Biomolecules · Quantitative Biology 2025-03-06 Jiajun Yu , Yizhen Zheng , Huan Yee Koh , Shirui Pan , Tianyue Wang , Haishuai Wang

Modern manufacturing demands high flexibility and reconfigurability to adapt to dynamic production needs. Model-based Engineering (MBE) supports rapid production line design, but final reconfiguration requires simulations and validation.…

In drug discovery, molecular docking aims at characterizing the binding of a drug-like molecule to a macromolecule. AutoDock-GPU, a state-of-the-art docking software, estimates the geometrical conformation of a docked ligand-protein complex…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-10-15 Gabin Schieffer , Ivy Peng

The massive trend of integrating data-driven AI capabilities into traditional software systems is rising new intriguing challenges. One of such challenges is achieving a smooth transition from the explorative phase of Machine Learning…

Software Engineering · Computer Science 2022-05-25 Luigi Quaranta

Data preprocessing pipelines, which includes data decoding, cleaning, and transforming, are a crucial component of Machine Learning (ML) training. Thy are computationally intensive and often become a major bottleneck, due to the increasing…

Hardware Architecture · Computer Science 2024-09-24 Yu Zhu , Wenqi Jiang , Gustavo Alonso

Data scientists seeking a good supervised learning model on a new dataset have many choices to make: they must preprocess the data, select features, possibly reduce the dimension, select an estimation algorithm, and choose hyperparameters…

Machine Learning · Computer Science 2020-06-11 Chengrun Yang , Jicong Fan , Ziyang Wu , Madeleine Udell

In this paper, we have gone through different AI-Based frameworks used for various educational tasks like digital customized assignment allotment and performance monitoring, identifying slow-learners and fast-learners, etc. application…

Human-Computer Interaction · Computer Science 2024-10-17 S. Tamang , D. J. Bora

In this work we introduce Disease Progression Modeling workbench 360 (DPM360) opensource clinical informatics framework for collaborative research and delivery of healthcare AI. DPM360, when fully developed, will manage the entire modeling…

‹ Prev 1 8 9 10 Next ›