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Few-shot learning (FSL) aims to recognize novel concepts from only a few labeled support samples. Recent studies enhance support features by incorporating additional semantic information or designing complex semantic fusion modules.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Wenhao Li , Qiangchang Wang , Xianjing Meng , Zhibin Wu , Yilong Yin

Rare cancers comprise 20-25% of all malignancies but face major diagnostic challenges due to limited expert availability-especially in pediatric oncology, where they represent over 70% of cases. While pathology vision-language (VL)…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Dexuan He , Xiao Zhou , Wenbin Guan , Liyuan Zhang , Xiaoman Zhang , Sinuo Xu , Ge Wang , Lifeng Wang , Xiaojun Yuan , Xin Sun , Yanfeng Wang , Kun Sun , Ya Zhang , Weidi Xie

Whole slide images (WSIs) are the gold standard for pathological diagnosis and sub-typing. Current main-stream two-step frameworks employ offline feature encoders trained without domain-specific knowledge. Among them, attention-based…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Mingrui Ma , Chentao Li , Pan Huang , Jing Qin

In computational pathology, weak supervision has become the standard for deep learning due to the gigapixel scale of WSIs and the scarcity of pixel-level annotations, with Multiple Instance Learning (MIL) established as the principal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Andreas Lolos , Theofilos Christodoulou , Aris L. Moustakas , Stergios Christodoulidis , Maria Vakalopoulou

Large-scale vision-language models (VLMs), trained on extensive datasets of image-text pairs, exhibit strong multimodal understanding capabilities by implicitly learning associations between textual descriptions and image regions. This…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Mir Rayat Imtiaz Hossain , Mennatullah Siam , Leonid Sigal , James J. Little

Multimodal learning has shown promise in medical imaging, combining complementary modalities like images and text. Vision-language models (VLMs) capture rich diagnostic cues but often require large paired datasets and prompt- or text-based…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Banafsheh Karimian , Giulia Avanzato , Soufian Belharbi , Alexis Guichemerre , Luke McCaffrey , Mohammadhadi Shateri , Eric Granger

Multiple instance learning (MIL) is an effective and widely used approach for weakly supervised machine learning. In histopathology, MIL models have achieved remarkable success in tasks like tumor detection, biomarker prediction, and…

Analysis of histopathology slides is a critical step for many diagnoses, and in particular in oncology where it defines the gold standard. In the case of digital histopathological analysis, highly trained pathologists must review vast…

Computer Vision and Pattern Recognition · Computer Science 2020-02-21 Pierre Courtiol , Eric W. Tramel , Marc Sanselme , Gilles Wainrib

The Vision Foundation Model has recently gained attention in medical image analysis. Its zero-shot learning capabilities accelerate AI deployment and enhance the generalizability of clinical applications. However, segmenting pathological…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Can Cui , Ruining Deng , Junlin Guo , Quan Liu , Tianyuan Yao , Haichun Yang , Yuankai Huo

We propose general visual inspection model using Vision-Language Model~(VLM) with few-shot images of non-defective or defective products, along with explanatory texts that serve as inspection criteria. Although existing VLM exhibit high…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Shiryu Ueno , Yoshikazu Hayashi , Shunsuke Nakatsuka , Yusei Yamada , Hiroaki Aizawa , Kunihito Kato

Vision-language models such as CLIP are capable of mapping the different modality data into a unified feature space, enabling zero/few-shot inference by measuring the similarity of given images and texts. However, most existing methods…

Computer Vision and Pattern Recognition · Computer Science 2024-07-29 Xingyu Zhu , Beier Zhu , Yi Tan , Shuo Wang , Yanbin Hao , Hanwang Zhang

Multiple Instance Learning (MIL) has emerged as a promising paradigm for Whole Slide Image (WSI) diagnosis, offering effective learning with limited annotations. However, existing MIL frameworks overlook diagnostic priorities and fail to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Sungrae Hong , Jiwon Jeong , Jisu Shin , Donghee Han , Sol Lee , Kyungeun Kim , Mun Yong Yi

Existing vision-language models (VLMs) such as CLIP have showcased an impressive capability to generalize well across various downstream tasks. These models leverage the synergy between visual and textual information, enabling them to…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Fangming Cui , Yonggang Zhang , Xuan Wang , Xule Wang , Liang Xiao

Large Vision-Language Models (VLMs) are increasingly being regarded as foundation models that can be instructed to solve diverse tasks by prompting, without task-specific training. We examine the seemingly obvious question: how to…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Niccolo Avogaro , Thomas Frick , Mattia Rigotti , Andrea Bartezzaghi , Filip Janicki , Cristiano Malossi , Konrad Schindler , Roy Assaf

Low-shot image classification, where training images are limited or inaccessible, has benefited from recent progress on pre-trained vision-language (VL) models with strong generalizability, e.g. CLIP. Prompt learning methods built with VL…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Zhaoheng Zheng , Jingmin Wei , Xuefeng Hu , Haidong Zhu , Ram Nevatia

Weakly supervised whole slide image (WSI) classification is challenging due to the lack of patch-level labels and high computational costs. State-of-the-art methods use self-supervised patch-wise feature representations for multiple…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Wentao Huang , Xiaoling Hu , Shahira Abousamra , Prateek Prasanna , Chao Chen

Multiple instance learning (MIL) has been extensively applied to whole slide histopathology image (WSI) analysis. The existing aggregation strategy in MIL, which primarily relies on the first-order distance (e.g., mean difference) between…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Yihang Chen , Tsai Hor Chan , Guosheng Yin , Yuming Jiang , Lequan Yu

Vision-language models (VLMs) have gained significant attention in computational pathology due to their multimodal learning capabilities that enhance big-data analytics of giga-pixel whole slide image (WSI). However, their sensitivity to…

Computer Vision and Pattern Recognition · Computer Science 2025-05-02 Vasudev Sharma , Ahmed Alagha , Abdelhakim Khellaf , Vincent Quoc-Huy Trinh , Mahdi S. Hosseini

Weakly supervised semantic segmentation (WSSS) in histopathology seeks to reduce annotation cost by learning from image-level labels, yet it remains limited by inter-class homogeneity, intra-class heterogeneity, and the region-shrinkage…

Accurate annotation of cutaneous neoplasm biopsies represents a major challenge due to their wide morphological variability, overlapping histological patterns, and the subtle distinctions between benign and malignant lesions.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Santiago Moreno , Pablo Meseguer , Rocío del Amor , Valery Naranjo