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Time series with long-term structure arise in a variety of contexts and capturing this temporal structure is a critical challenge in time series analysis for both inference and forecasting settings. Traditionally, state space models have…
Low-Rank Adaptation (LoRA) is widely adopted for downstream fine-tuning of foundation models due to its efficiency and zero additional inference cost. Many real-world applications require foundation models to specialize in several specific…
Fine-tuning has proven to be highly effective in adapting pre-trained models to perform better on new desired tasks with minimal data samples. Among the most widely used approaches are reparameterization methods, which update a target…
Parameter-efficient fine-tuning (PEFT) techniques such as low-rank adaptation (LoRA) can effectively adapt large pre-trained foundation models to downstream tasks using only a small fraction (0.1%-10%) of the original trainable weights. An…
Despite large neural networks demonstrating remarkable abilities to complete different tasks, they require excessive memory usage to store the optimization states for training. To alleviate this, the low-rank adaptation (LoRA) is proposed…
We present techniques for speeding up the test-time evaluation of large convolutional networks, designed for object recognition tasks. These models deliver impressive accuracy but each image evaluation requires millions of floating point…
Low-Rank Adaptation (LoRA) has emerged as one of the most widely used parameter-efficient fine-tuning (PEFT) methods for adapting large language models (LLMs) to downstream tasks. While highly effective in single-task settings, it struggles…
Topological data analysis (TDA) detects geometric structure in biological data. However, many TDA algorithms are memory intensive and impractical for massive datasets. Here, we introduce a statistical protocol that reduces TDA's memory…
There has been a significant increase in the deployment of neural network models, presenting substantial challenges in model adaptation and fine-tuning. Efficient adaptation is crucial in maintaining model performance across diverse tasks…
Scaling up model depth and size is now a common approach to raise accuracy in many deep learning (DL) applications, as evidenced by the widespread success of multi-billion or even trillion parameter models in natural language processing…
Modern Transformer-based models frequently suffer from miscalibration, producing overconfident predictions that do not reflect true empirical frequencies. This work investigates the calibration dynamics of LoRA: Low-Rank Adaptation and a…
Deep learning has been widely used for protein engineering. However, it is limited by the lack of sufficient experimental data to train an accurate model for predicting the functional fitness of high-order mutants. Here, we develop SESNet,…
This letter introduces ERRA, an embodied learning architecture that enables robots to jointly obtain three fundamental capabilities (reasoning, planning, and interaction) for solving long-horizon language-conditioned manipulation tasks.…
In this work we introduce RITA: a suite of autoregressive generative models for protein sequences, with up to 1.2 billion parameters, trained on over 280 million protein sequences belonging to the UniRef-100 database. Such generative models…
In this paper, we propose an end-to-end deep learning model, called E2Efold, for RNA secondary structure prediction which can effectively take into account the inherent constraints in the problem. The key idea of E2Efold is to directly…
Many real-world systems studied are governed by complex, nonlinear dynamics. By modeling these dynamics, we can gain insight into how these systems work, make predictions about how they will behave, and develop strategies for controlling…
Low-rank adaptation (LoRA) has been widely adopted as a parameter-efficient technique for fine-tuning large-scale pre-trained models. However, it still lags behind full fine-tuning in performance, partly due to its insufficient exploitation…
Pre-training Large Language Models (LLMs) on web-scale datasets becomes fundamental for advancing general-purpose AI. In contrast, enhancing their predictive performance on downstream tasks typically involves adapting their knowledge…
Deep Learning's recent successes have mostly relied on Convolutional Networks, which exploit fundamental statistical properties of images, sounds and video data: the local stationarity and multi-scale compositional structure, that allows…
Background: Small interfering RNA (siRNA) is a promising therapeutic agent due to its ability to silence disease-related genes via RNA interference. While traditional machine learning and early deep learning methods have made progress in…